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2-Hydroxyxanthone

CAS# 1915-98-6

2-Hydroxyxanthone

Catalog No. BCN7545----Order now to get a substantial discount!

Product Name & Size Price Stock
2-Hydroxyxanthone: 5mg $529 In Stock
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Quality Control of 2-Hydroxyxanthone

Number of papers citing our products

Chemical structure

2-Hydroxyxanthone

3D structure

Chemical Properties of 2-Hydroxyxanthone

Cas No. 1915-98-6 SDF Download SDF
PubChem ID 74708 Appearance Powder
Formula C13H8O3 M.Wt 212.20
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-hydroxyxanthen-9-one
SMILES C1=CC=C2C(=C1)C(=O)C3=C(O2)C=CC(=C3)O
Standard InChIKey WSACHQJPCNOREV-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H8O3/c14-8-5-6-12-10(7-8)13(15)9-3-1-2-4-11(9)16-12/h1-7,14H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2-Hydroxyxanthone

The twigs of Calophyllum inophyllum.

Biological Activity of 2-Hydroxyxanthone

Description2-Hydroxyxanthone is a natural product from Calophyllum inophyllum.
In vitro

Cytotoxic prenylated xanthones from Calophyllum inophyllum.[Pubmed: 19003621]

J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):993-7.


METHODS AND RESULTS:
A new prenylated xanthone (1), named caloxanthone N, together with two known constituents, gerontoxanthone C (2) and 2-Hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of Calophyllum inophyllum. Their structures were completely elucidated using a combination of 1D, 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analyses.
CONCLUSIONS:
Compounds 1 and 2 exhibited cytotoxicity against chronic myelogenous leukemia cell line (K562) with IC50 values of 7.2 and 6.3 microg ml(- 1), respectively.

2-Hydroxyxanthone Dilution Calculator

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2-Hydroxyxanthone Molarity Calculator

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Preparing Stock Solutions of 2-Hydroxyxanthone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7125 mL 23.5627 mL 47.1254 mL 94.2507 mL 117.8134 mL
5 mM 0.9425 mL 4.7125 mL 9.4251 mL 18.8501 mL 23.5627 mL
10 mM 0.4713 mL 2.3563 mL 4.7125 mL 9.4251 mL 11.7813 mL
50 mM 0.0943 mL 0.4713 mL 0.9425 mL 1.885 mL 2.3563 mL
100 mM 0.0471 mL 0.2356 mL 0.4713 mL 0.9425 mL 1.1781 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 2-Hydroxyxanthone

Cytotoxic prenylated xanthones from Calophyllum inophyllum.[Pubmed:19003621]

J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):993-7.

A new prenylated xanthone (1), named caloxanthone N, together with two known constituents, gerontoxanthone C (2) and 2-Hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of Calophyllum inophyllum. Their structures were completely elucidated using a combination of 1D, 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analyses. Compounds 1 and 2 exhibited cytotoxicity against chronic myelogenous leukemia cell line (K562) with IC50 values of 7.2 and 6.3 microg ml(- 1), respectively.

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