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Tenacissoside G

CAS# 191729-43-8

Tenacissoside G

2D Structure

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Tenacissoside G: 5mg $63 In Stock
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Quality Control of Tenacissoside G

3D structure

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Tenacissoside G

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Chemical Properties of Tenacissoside G

Cas No. 191729-43-8 SDF Download SDF
PubChem ID 44561398 Appearance Powder
Formula C42H64O14 M.Wt 792.96
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC=C(C)C(=O)OC1C2C3(CCC(CC3CCC24C5(O4)CCC(C5(C1OC(=O)C)C)C(=O)C)OC6CC(C(C(O6)C)OC7C(C(C(C(O7)C)O)OC)O)OC)C
Standard InChIKey OHDJGUWKOIBIKY-SGFNNURDSA-N
Standard InChI InChI=1S/C42H64O14/c1-11-20(2)37(47)54-34-35-39(7)15-13-26(53-29-19-28(48-9)32(23(5)50-29)55-38-31(46)33(49-10)30(45)22(4)51-38)18-25(39)12-16-41(35)42(56-41)17-14-27(21(3)43)40(42,8)36(34)52-24(6)44/h11,22-23,25-36,38,45-46H,12-19H2,1-10H3/b20-11+/t22-,23-,25+,26+,27+,28-,29+,30-,31-,32-,33-,34+,35-,36-,38+,39+,40+,41+,42-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Tenacissoside G

The herbs of Marsdenia tenacissima

Biological Activity of Tenacissoside G

DescriptionTenacissoside G is a natural product from Marsdenia tenacissima.

Protocol of Tenacissoside G

Structure Identification
Yao Xue Xue Bao. 2008 May;43(5):509-12.

C21 steroids from the stems of Marsdenia tenacissima.[Pubmed: 18717339]

To study the C21 steroids of the stems of Marsdenia tenacissima (Roxb.) Wight et Arn, various chromatography methods were used for the isolation of the constituents and their structures were identified by spectral analysis.
METHODS AND RESULTS:
Eight C21 steroids were isolated from the CHCl3 extract, which were identified as 11alpha-O-tigloyl-17beta-tenacigenin B (1), 17beta-tenacigenin B (2), tenacigenoside A (3), 11alpha-O-2-methylbutyryl-12beta-O-acetyl tenacigenin B (4), tenacissoside H (5), marsdenoside A (6), Tenacissoside G (7), and tenacissoside I (8). Among them, compound 1 is a new compound.

Tenacissoside G Dilution Calculator

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Tenacissoside G Molarity Calculator

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Preparing Stock Solutions of Tenacissoside G

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2611 mL 6.3055 mL 12.611 mL 25.222 mL 31.5274 mL
5 mM 0.2522 mL 1.2611 mL 2.5222 mL 5.0444 mL 6.3055 mL
10 mM 0.1261 mL 0.6305 mL 1.2611 mL 2.5222 mL 3.1527 mL
50 mM 0.0252 mL 0.1261 mL 0.2522 mL 0.5044 mL 0.6305 mL
100 mM 0.0126 mL 0.0631 mL 0.1261 mL 0.2522 mL 0.3153 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tenacissoside G

[C21 steroids from the stems of Marsdenia tenacissima].[Pubmed:18717339]

Yao Xue Xue Bao. 2008 May;43(5):509-12.

To study the C21 steroids of the stems of Marsdenia tenacissima (Roxb.) Wight et Arn, various chromatography methods were used for the isolation of the constituents and their structures were identified by spectral analysis. Eight C21 steroids were isolated from the CHCl3 extract, which were identified as 11alpha-O-tigloyl-17beta-tenacigenin B (1), 17beta-tenacigenin B (2), tenacigenoside A (3), 11alpha-O-2-methylbutyryl-12beta-O-acetyl tenacigenin B (4), tenacissoside H (5), marsdenoside A (6), Tenacissoside G (7), and tenacissoside I (8). Among them, compound 1 is a new compound.

Description

Tenacissoside G is a C21 steroid from the stems of Marsdenia tenacissima. Tenacissoside G reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells.

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