Home >> Research Area >>Natural Products>>Triterpenoids>> 23-Hydroxybetulin

23-Hydroxybetulin

CAS# 84414-40-4

23-Hydroxybetulin

Catalog No. BCN6463----Order now to get a substantial discount!

Product Name & Size Price Stock
23-Hydroxybetulin: 5mg $776 In Stock
23-Hydroxybetulin: 10mg Please Inquire In Stock
23-Hydroxybetulin: 20mg Please Inquire Please Inquire
23-Hydroxybetulin: 50mg Please Inquire Please Inquire
23-Hydroxybetulin: 100mg Please Inquire Please Inquire
23-Hydroxybetulin: 200mg Please Inquire Please Inquire
23-Hydroxybetulin: 500mg Please Inquire Please Inquire
23-Hydroxybetulin: 1000mg Please Inquire Please Inquire

Quality Control of 23-Hydroxybetulin

Number of papers citing our products

Chemical structure

23-Hydroxybetulin

3D structure

Chemical Properties of 23-Hydroxybetulin

Cas No. 84414-40-4 SDF Download SDF
PubChem ID 14605681 Appearance Powder
Formula C30H50O3 M.Wt 458.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,3aS,5aR,5bR,7aR,8R,9S,11aR,11bR,13aR,13bR)-3a,8-bis(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol
SMILES CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)CO)O)C)CO
Standard InChIKey PHMKDBZGQWXPAZ-MZFJGDBOSA-N
Standard InChI InChI=1S/C30H50O3/c1-19(2)20-9-14-30(18-32)16-15-28(5)21(25(20)30)7-8-23-26(3)12-11-24(33)27(4,17-31)22(26)10-13-29(23,28)6/h20-25,31-33H,1,7-18H2,2-6H3/t20-,21+,22+,23+,24-,25+,26-,27-,28+,29+,30+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 23-Hydroxybetulin

The barks of Betula alba L.

Biological Activity of 23-Hydroxybetulin

Description23-Hydroxybetulin is a natural product from Betula alba L.

Protocol of 23-Hydroxybetulin

Structure Identification
Planta Med. 2016 Sep;82(14):1302-7.

An HPLC-ELSD Method for the Determination of Triterpenes in Sorbus decora and Sorbus americana Bark Used by the Eeyou Istchee Cree First Nation.[Pubmed: 27163231]


METHODS AND RESULTS:
The extraction method reproducibly recovered the compounds above 70 % and the chromatographic separation of betulin, 23-Hydroxybetulin, 23,28-dihydroxylupan-20(29)-ene-3β-caffeate, betulinic acid, α-amyrin, uvaol, 3β,23,28-trihydroxy-12-ursene, and 23,28-dihydroxyursan-12-ene-3β-caffeate was achieved within 27 min by linear gradient. The method produced highly reproducible quantitative data at interday and intraday levels. The limits of detection were in the ng level on-column with remarkable range and linearity. The target compounds were present at mg levels in the populations, collected from inland (Mistissini and Nemaska) and costal (Waskagnish and Chisasibi) Cree communities of northern Quebec. A triterpene, 23-Hydroxybetulin, was the most abundant, while betulinic acid and uvaol were minor constituents.
CONCLUSIONS:
Overall, HPLC-ELSD analyses produced very similar profiles and contents of the eight compounds in the plants collected from four geographic locations. The developed HPLC-ELSD method can be used as a targeted analysis of triterpenes in these medicinal plants.

23-Hydroxybetulin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

23-Hydroxybetulin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 23-Hydroxybetulin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1801 mL 10.9004 mL 21.8007 mL 43.6015 mL 54.5019 mL
5 mM 0.436 mL 2.1801 mL 4.3601 mL 8.7203 mL 10.9004 mL
10 mM 0.218 mL 1.09 mL 2.1801 mL 4.3601 mL 5.4502 mL
50 mM 0.0436 mL 0.218 mL 0.436 mL 0.872 mL 1.09 mL
100 mM 0.0218 mL 0.109 mL 0.218 mL 0.436 mL 0.545 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 23-Hydroxybetulin

An HPLC-ELSD Method for the Determination of Triterpenes in Sorbus decora and Sorbus americana Bark Used by the Eeyou Istchee Cree First Nation.[Pubmed:27163231]

Planta Med. 2016 Sep;82(14):1302-7.

Sorbus decora and Sorbus americana are used traditionally as medicine by the Eeyou Istchee Cree First Nation of the James Bay region of Quebec, Canada. Because the ethanol extracts of the bark and the isolated terpenes of these plants have shown promising in vivo antidiabetic effects, an analytical method was developed and validated by RP-HPLC-ELSD for the identification and quantification of eight lupane- and ursane-type terpenes. The extraction method reproducibly recovered the compounds above 70 % and the chromatographic separation of betulin, 23-hydroxy-betulin, 23,28-dihydroxylupan-20(29)-ene-3beta-caffeate, betulinic acid, alpha-amyrin, uvaol, 3beta,23,28-trihydroxy-12-ursene, and 23,28-dihydroxyursan-12-ene-3beta-caffeate was achieved within 27 min by linear gradient. The method produced highly reproducible quantitative data at interday and intraday levels. The limits of detection were in the ng level on-column with remarkable range and linearity. The target compounds were present at mg levels in the populations, collected from inland (Mistissini and Nemaska) and costal (Waskagnish and Chisasibi) Cree communities of northern Quebec. A triterpene, 23-Hydroxybetulin, was the most abundant, while betulinic acid and uvaol were minor constituents. Overall, HPLC-ELSD analyses produced very similar profiles and contents of the eight compounds in the plants collected from four geographic locations. The developed HPLC-ELSD method can be used as a targeted analysis of triterpenes in these medicinal plants.

Keywords:

23-Hydroxybetulin,84414-40-4,Natural Products, buy 23-Hydroxybetulin , 23-Hydroxybetulin supplier , purchase 23-Hydroxybetulin , 23-Hydroxybetulin cost , 23-Hydroxybetulin manufacturer , order 23-Hydroxybetulin , high purity 23-Hydroxybetulin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: