5-O-MethylvisammiosideCAS# 84272-85-5 |
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| Cas No. | 84272-85-5 | SDF | Download SDF |
| PubChem ID | 21670038 | Appearance | Beige crystalline |
| Formula | C22H28O10 | M.Wt | 452.46 |
| Type of Compound | Polyphenols | Storage | Desiccate at -20°C |
| Synonyms | 4'-O-β-D-Glucosyl-5-O-methylvisamminol | ||
| Solubility | Soluble in methan | ||
| Chemical Name | (2S)-4-methoxy-7-methyl-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-5-one | ||
| SMILES | CC1=CC(=O)C2=C(C3=C(C=C2O1)OC(C3)C(C)(C)OC4C(C(C(C(O4)CO)O)O)O)OC | ||
| Standard InChIKey | QVGFPTYGKPLXPK-OOBAEQHESA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 5-O-Methylvisammioside is a naturally occuring product isolated from Saposhnikovia Divaricata and has analgesic, antipyretic, anti-inflammatory and anti-platelet aggregation effects. |
| Structure Identification | Phytochem Anal. 2011 Jul-Aug;22(4):313-21.Application of response surface methodology to optimise ultrasonic-assisted extraction of four chromones in Radix Saposhnikoviae.[Pubmed: 21438050]Radix Saposhnikoviae is one of the most famous Chinese herbal medicines with many pharmacological activities towards inflammatory symptoms and antioxidation. Chromones are considered as one of the effective components. It is important to find a reasonable method to extract the chromones in S. divaricata.
To develop an ultrasonic-assisted extraction (UAE) to extract chromones in Radix Saposhnikoviae and to optimise extraction conditions.
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5-O-Methylvisammioside Dilution Calculator
5-O-Methylvisammioside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2101 mL | 11.0507 mL | 22.1014 mL | 44.2028 mL | 55.2535 mL |
| 5 mM | 0.442 mL | 2.2101 mL | 4.4203 mL | 8.8406 mL | 11.0507 mL |
| 10 mM | 0.221 mL | 1.1051 mL | 2.2101 mL | 4.4203 mL | 5.5254 mL |
| 50 mM | 0.0442 mL | 0.221 mL | 0.442 mL | 0.8841 mL | 1.1051 mL |
| 100 mM | 0.0221 mL | 0.1105 mL | 0.221 mL | 0.442 mL | 0.5525 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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5-O-Methylvisammioside is a natural product isolated from Saposhnikovia Divaricata.
References:
[1]. HAN Zhong-Ming, et al. Separation and Purification of Prim-O-glucosylcimifugin and 5-O-methylvisammioside from Saposhnikovia Divaricata by High-speed Counter-current Chromatography. Chinese Journal of Analytical Chemistry, 2009-11
[2]. YAN Ye-xia, et al. RP-HPLC determination of 5-O-methylvisammioside in Fangfeng Tongsheng Wan. Central South Pharmacy, 2012-02
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Application of response surface methodology to optimise ultrasonic-assisted extraction of four chromones in Radix Saposhnikoviae.[Pubmed:21438050]
Phytochem Anal. 2011 Jul-Aug;22(4):313-21.
INTRODUCTION: Radix Saposhnikoviae is one of the most famous Chinese herbal medicines with many pharmacological activities towards inflammatory symptoms and antioxidation. Chromones are considered as one of the effective components. It is important to find a reasonable method to extract the chromones in S. divaricata. OBJECTIVE: To develop an ultrasonic-assisted extraction (UAE) to extract chromones in Radix Saposhnikoviae and to optimise extraction conditions. METHODOLOGY: Four chromones (prim-O-glucosylcimifugin, cimifugin, 5-O-Methylvisammioside and sec-O-glucosylhamaudol) were extracted by the UAE method combined with response surface methodology (RSM). Box-Behnken design (BBD) was applied to evaluate the effects of three independent variables (ethanol concentration, extraction time and extraction temperature) on the chromones yield of Radix Saposhnikoviae. RESULTS: Correlation analysis of the mathematical-regression model indicated that a quadratic polynomial model could be employed to optimise the extraction of chromones by UAE method. The optimal conditions to obtain the highest chromones yield of Radix Saposhnikoviae were a solvent of 75% ethanol, an extraction time of 48 min and an extraction temperature of 67 degrees C. CONCLUSION: Under these optimal conditions, the experimental values agreed closely with the predicted values. The analysis of variance indicated a high goodness of model fit and the success of RSM method for optimising chromones extraction in Radix Saposhnikoviae.
