4',5,7-Trihydroxy-6-prenylflavoneCAS# 68097-13-2 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 68097-13-2 | SDF | Download SDF |
| PubChem ID | 10382485 | Appearance | Yellow powder |
| Formula | C20H18O5 | M.Wt | 338.4 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one | ||
| SMILES | CC(=CCC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=C(C=C3)O)O)C | ||
| Standard InChIKey | VJDRSTHNWHVTNQ-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. 6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. 2. 6-Prenylapigenin shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines. |
4',5,7-Trihydroxy-6-prenylflavone Dilution Calculator
4',5,7-Trihydroxy-6-prenylflavone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.9551 mL | 14.7754 mL | 29.5508 mL | 59.1017 mL | 73.8771 mL |
| 5 mM | 0.591 mL | 2.9551 mL | 5.9102 mL | 11.8203 mL | 14.7754 mL |
| 10 mM | 0.2955 mL | 1.4775 mL | 2.9551 mL | 5.9102 mL | 7.3877 mL |
| 50 mM | 0.0591 mL | 0.2955 mL | 0.591 mL | 1.182 mL | 1.4775 mL |
| 100 mM | 0.0296 mL | 0.1478 mL | 0.2955 mL | 0.591 mL | 0.7388 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Boc-Phe(4-Cl)-OH
Catalog No.:BCC3172
CAS No.:68090-88-0
- Norfloxacin hydrochloride
Catalog No.:BCC4230
CAS No.:68077-27-0
- Trifolirhizin
Catalog No.:BCN4237
CAS No.:6807-83-6
- Megastigm-7-ene-3,5,6,9-tetraol
Catalog No.:BCN5169
CAS No.:680617-50-9
- EMPA
Catalog No.:BCC6226
CAS No.:680590-49-2
- Platyconic acid A
Catalog No.:BCN3239
CAS No.:68051-23-0
- Escin
Catalog No.:BCC8323
CAS No.:6805-41-0
- (Z)-4-Hydroxytamoxifen
Catalog No.:BCC6015
CAS No.:68047-06-3
- Carbadox
Catalog No.:BCC3744
CAS No.:6804-07-5
- Pulsatilla saponin D
Catalog No.:BCN8526
CAS No.:68027-15-6
- Pulsatilla saponin H
Catalog No.:BCN8181
CAS No.:68027-14-5
- Magnocurarine
Catalog No.:BCN3839
CAS No.:6801-40-7
- Bepridil hydrochloride
Catalog No.:BCC7864
CAS No.:68099-86-5
- 13-Dehydroxyindaconintine
Catalog No.:BCN8403
CAS No.:681-18-9
- AICAR phosphate
Catalog No.:BCC4220
CAS No.:681006-28-0
- JNJ-1661010
Catalog No.:BCC2315
CAS No.:681136-29-8
- Roburic acid
Catalog No.:BCN5385
CAS No.:6812-81-3
- Royleanone
Catalog No.:BCN3917
CAS No.:6812-87-9
- Chonglou Saponin VII
Catalog No.:BCN4239
CAS No.:68124-04-9
- Astressin 2B
Catalog No.:BCC5906
CAS No.:681260-70-8
- Diosgenyl-3-di-β-O-glucopyranoside
Catalog No.:BCC8168
CAS No.:68127-19-5
- Humic acid sodium salt
Catalog No.:BCN1284
CAS No.:68131-04-4
- Jujuboside B1
Catalog No.:BCN3881
CAS No.:68144-21-8
- 1-O-Acetyl britannilactone
Catalog No.:BCN2365
CAS No.:681457-46-5
Artocarpus plants as a potential source of skin whitening agents.[Pubmed:21941923]
Nat Prod Commun. 2011 Sep;6(9):1397-402.
Artocarpus plants have been a focus of constant attention due to the potential for skin whitening agents. In the in vitro experiment, compounds from the Artocarpus plants, such as artocarpanone, norartocarpetin, artocarpesin, artogomezianol, andalasin, artocarbene, and chlorophorin showed tyrosinase inhibitory activity. Structure-activity investigations revealed that the 4-substituted resorcinol moiety in these compounds was responsible for their potent inhibitory activities on tyrosinase. In the in vitro assay, using B16 melanoma cells, the prenylated polyphenols isolated from Artocarpus plants, such as artocarpin, cudraflavone C, 6-prenylapigenin, kuwanon C, norartocarpin, albanin A, cudraflavone B, and brosimone I showed potent inhibitory activity on melanin formation. Structure-activity investigations revealed that the introduction of an isoprenoid moiety to a non-isoprenoid-substituted polyphenol enhanced the inhibitory activity of melanin production in B16 melanoma cells. In the in vivo investigation, the extract of the wood of Artocarpus incisus and a representative isolated compound from it, artocarpin had a lightening effect on the skin of guinea pigs' backs. Other in vivo experiments using human volunteers have shown that water extract of Artocarpus lakoocha reduced the melanin formation in the skin of volunteers. These results indicate that the extracts of Artocarpus plants are potential sources for skin whitening agents.
