4-MethoxycoumarineCAS# 20280-81-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 20280-81-3 | SDF | Download SDF |
PubChem ID | 529426 | Appearance | Powder |
Formula | C10H8O3 | M.Wt | 176.17 |
Type of Compound | Coumarins | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 4-methoxychromen-2-one | ||
SMILES | COC1=CC(=O)OC2=CC=CC=C21 | ||
Standard InChIKey | MLCMXDYMSAZNPC-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C10H8O3/c1-12-9-6-10(11)13-8-5-3-2-4-7(8)9/h2-6H,1H3 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 4-Methoxycoumarin has antitumour effects. |
In vitro | Cytostatic activity of coumarin metabolites and derivatives in the B16-F10 murine melanoma cell line.[Reference: WebLink]Melanoma Research, 1999, 9(3):243-248.Coumarin has antitumour effects in vivo and cytostatic effects in vitro. Its half-life in humans is short (1-1.5 h) and the monohydroxylated biotransformation products have significantly longer half-lives. One or several of these products may thus be responsible for the antitumoral effects.
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4-Methoxycoumarine Dilution Calculator
4-Methoxycoumarine Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 5.6763 mL | 28.3817 mL | 56.7634 mL | 113.5267 mL | 141.9084 mL |
5 mM | 1.1353 mL | 5.6763 mL | 11.3527 mL | 22.7053 mL | 28.3817 mL |
10 mM | 0.5676 mL | 2.8382 mL | 5.6763 mL | 11.3527 mL | 14.1908 mL |
50 mM | 0.1135 mL | 0.5676 mL | 1.1353 mL | 2.2705 mL | 2.8382 mL |
100 mM | 0.0568 mL | 0.2838 mL | 0.5676 mL | 1.1353 mL | 1.4191 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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