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5-Aminoindazole

CAS# 19335-11-6

5-Aminoindazole

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Product Name & Size Price Stock
5-Aminoindazole: 5mg $17 In Stock
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Quality Control of 5-Aminoindazole

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Chemical structure

5-Aminoindazole

3D structure

Chemical Properties of 5-Aminoindazole

Cas No. 19335-11-6 SDF Download SDF
PubChem ID 88012 Appearance Powder
Formula C7H7N3 M.Wt 133
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1H-indazol-5-amine
SMILES C1=CC2=C(C=C1N)C=NN2
Standard InChIKey XBTOSRUBOXQWBO-UHFFFAOYSA-N
Standard InChI InChI=1S/C7H7N3/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,8H2,(H,9,10)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

5-Aminoindazole Dilution Calculator

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5-Aminoindazole Molarity Calculator

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Preparing Stock Solutions of 5-Aminoindazole

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 7.5188 mL 37.594 mL 75.188 mL 150.3759 mL 187.9699 mL
5 mM 1.5038 mL 7.5188 mL 15.0376 mL 30.0752 mL 37.594 mL
10 mM 0.7519 mL 3.7594 mL 7.5188 mL 15.0376 mL 18.797 mL
50 mM 0.1504 mL 0.7519 mL 1.5038 mL 3.0075 mL 3.7594 mL
100 mM 0.0752 mL 0.3759 mL 0.7519 mL 1.5038 mL 1.8797 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Aminoindazole

Dispersion enhancing effect of sonochemically functionalized graphene oxide for catalysing antioxidant efficacy of curcumin.[Pubmed:28732937]

Ultrason Sonochem. 2017 Nov;39:208-217.

The non-hazardous sonochemical approach has been developed for the functionalization of graphene oxide (GrO) with 5-Aminoindazole (5-AIND). The formation of f-(5-AIND) GrO is confirmed with (13)C solid state NMR, HRXPS, XRD, Raman, TGA, DSC, FTIR etc. The >80% cell viabilities on MCF-7 and Vero cell lines have confirmed the high cytocompatibility of f-(5-AIND) GrO. Additionally, the morphological impact on Vero cell line has evidently confirmed the biocompatibility of f-(5-AIND) GrO. As compared to GrO, the f-(5-AIND) GrO has demonstrated an enhanced antioxidant efficacy of 69.4-72%, evaluated with 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical assay. With a similar objective (0.01-0.05)mL peanut oil based curcumin micro and nanoemulsions have been prepared using ethanol and glycerol as co-solvent and co-surfactant respectively. The prepared emulsions are subsequently characterised with respect to morphological and physicochemical parameters via density, surface tension, viscosity, friccohesity measurement and DLS analysis. Henceforth, with an expectation to achieve higher dispersion, an ethanolic dispersion of f-(5-AIND) GrO has been mixed with curcumin carrying emulsions in 1:1. Notably, the radical scavenging activities (RSA) of the combined formulations are significantly enhanced to an extent of 26.6%.

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