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6-Hydroxy-1,2,3,7-tetramethoxyxanthone

CAS# 64756-87-2

6-Hydroxy-1,2,3,7-tetramethoxyxanthone

2D Structure

Catalog No. BCN7565----Order now to get a substantial discount!

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6-Hydroxy-1,2,3,7-tetramethoxyxanthone: 5mg $960 In Stock
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Quality Control of 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

3D structure

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6-Hydroxy-1,2,3,7-tetramethoxyxanthone

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Chemical Properties of 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

Cas No. 64756-87-2 SDF Download SDF
PubChem ID 71378875 Appearance Powder
Formula C17H16O7 M.Wt 332.30
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-hydroxy-1,2,3,7-tetramethoxyxanthen-9-one
SMILES COC1=C(C=C2C(=C1)C(=O)C3=C(C(=C(C=C3O2)OC)OC)OC)O
Standard InChIKey MLDGGHTUGFLZII-UHFFFAOYSA-N
Standard InChI InChI=1S/C17H16O7/c1-20-11-5-8-10(6-9(11)18)24-12-7-13(21-2)16(22-3)17(23-4)14(12)15(8)19/h5-7,18H,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

The roots of Polygala sibirica L.

Biological Activity of 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

Description6-Hydroxy-1,2,3,7-tetramethoxyxanthone is a natural product from Polygala sibirica L.

Protocol of 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

Structure Identification
Chin J Nat Med. 2014 Mar;12(3):225-8.

Chemical investigation of the roots of Polygala sibirica L.[Pubmed: 24702811 ]

To investigate the chemical constituents of the roots of Polygala sibirica L. (Polygalaceae)
METHODS AND RESULTS:
The isolation was performed by solvent extraction and various chromatographic techniques, including silica gel, Sephadex LH-20, ODS, semi-preparative HPLC, and preparative TLC. The chemical structures were elucidated based on extensive spectroscopic analysis, including HR-ESI-MS and 1D- and 2D-NMR spectroscopic data. A total of sixteen compounds, including five xanthones (5, 7-10), five saccharide esters (1, 3, 4, 12, 13), two flavonoids (14, 16), two triterpenoids (11, 15), one phenylpropanoid (6), and one benzophenone glycoside (2) were isolated. Their structures were determined as sibiricose A7 (1), sibiriphenone A (2), polygalatenoside A (3), polygalatenoside C (4), lancerin (5), 3, 4, 5-trimethoxycinnamic acid (6), 6-Hydroxy-1,2,3,7-tetramethoxyxanthone (7), 1, 3, 7-trihydroxy-2-methoxyxanthone (8), onjixanthone II (9), 1, 2, 3, 6, 7-pentamethoxyxanthone (10), presenegenin (11), 3'-O-3, 4, 5-trimethoxycinnamoyl-6-O-4-methoxy benzoyl sucrose (12), tenuifoliside C (13), 5, 3'-dihydroxy-7, 4'-dimethoxyflavonol-3-O-β-D-glucopyranoside (14), tenuifolin (15), and rhamnetin 3-O-β-D-glucopyranoside (16).
CONCLUSIONS:
Compounds 1 and 2 are two new compounds from P. sibirica.

6-Hydroxy-1,2,3,7-tetramethoxyxanthone Dilution Calculator

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6-Hydroxy-1,2,3,7-tetramethoxyxanthone Molarity Calculator

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Preparing Stock Solutions of 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0093 mL 15.0466 mL 30.0933 mL 60.1866 mL 75.2332 mL
5 mM 0.6019 mL 3.0093 mL 6.0187 mL 12.0373 mL 15.0466 mL
10 mM 0.3009 mL 1.5047 mL 3.0093 mL 6.0187 mL 7.5233 mL
50 mM 0.0602 mL 0.3009 mL 0.6019 mL 1.2037 mL 1.5047 mL
100 mM 0.0301 mL 0.1505 mL 0.3009 mL 0.6019 mL 0.7523 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 6-Hydroxy-1,2,3,7-tetramethoxyxanthone

Chemical investigation of the roots of Polygala sibirica L.[Pubmed:24702811]

Chin J Nat Med. 2014 Mar;12(3):225-8.

AIM: To investigate the chemical constituents of the roots of Polygala sibirica L. (Polygalaceae) METHOD: The isolation was performed by solvent extraction and various chromatographic techniques, including silica gel, Sephadex LH-20, ODS, semi-preparative HPLC, and preparative TLC. The chemical structures were elucidated based on extensive spectroscopic analysis, including HR-ESI-MS and 1D- and 2D-NMR spectroscopic data. RESULTS: A total of sixteen compounds, including five xanthones (5, 7-10), five saccharide esters (1, 3, 4, 12, 13), two flavonoids (14, 16), two triterpenoids (11, 15), one phenylpropanoid (6), and one benzophenone glycoside (2) were isolated. Their structures were determined as sibiricose A7 (1), sibiriphenone A (2), polygalatenoside A (3), polygalatenoside C (4), lancerin (5), 3, 4, 5-trimethoxycinnamic acid (6), 6-hydroxy-1, 2, 3, 7-tetramethoxyxanthone (7), 1, 3, 7-trihydroxy-2-methoxyxanthone (8), onjixanthone II (9), 1, 2, 3, 6, 7-pentamethoxyxanthone (10), presenegenin (11), 3'-O-3, 4, 5-trimethoxycinnamoyl-6-O-4-methoxy benzoyl sucrose (12), tenuifoliside C (13), 5, 3'-dihydroxy-7, 4'-dimethoxyflavonol-3-O-beta-D-glucopyranoside (14), tenuifolin (15), and rhamnetin 3-O-beta-D-glucopyranoside (16). CONCLUSION: Compounds 1 and 2 are two new compounds from P. sibirica.

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