Aristolactam AIICAS# 53948-07-5 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 53948-07-5 | SDF | Download SDF |
| PubChem ID | 148657 | Appearance | Yellow powder |
| Formula | C16H11NO3 | M.Wt | 265.3 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | COC1=C(C=C2C3=C1C4=CC=CC=C4C=C3NC2=O)O | ||
| Standard InChIKey | ZEKAIRFOYPDZNC-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Aristolochia debilis Sieb. et Zucc
| Description | 1. Aristolactam AII has cytotoxic activity. 2. Aristolactam AII shows platelet aggregation inhibitory activity. |
| Targets | PAFR |
Aristolactam AII Dilution Calculator
Aristolactam AII Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.7693 mL | 18.8466 mL | 37.6932 mL | 75.3864 mL | 94.2329 mL |
| 5 mM | 0.7539 mL | 3.7693 mL | 7.5386 mL | 15.0773 mL | 18.8466 mL |
| 10 mM | 0.3769 mL | 1.8847 mL | 3.7693 mL | 7.5386 mL | 9.4233 mL |
| 50 mM | 0.0754 mL | 0.3769 mL | 0.7539 mL | 1.5077 mL | 1.8847 mL |
| 100 mM | 0.0377 mL | 0.1885 mL | 0.3769 mL | 0.7539 mL | 0.9423 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis.[Pubmed:23158725]
Phytochemistry. 2013 Feb;86:121-6.
Chemical investigation of the CH(2)Cl(2)/CH(3)OH extracts from aerial parts of the Australian plant Goniothalamus australis has resulted in the isolation of two pyridocoumarin alkaloids, goniothalines A (1) and B (2) as well as eight known natural products, Aristolactam AII (3), enterocarpam II (4), caldensine (5), sauristolactam (6), (-)-anonaine (7), asimilobine (8), altholactone (9) and (+)-goniofufurone (10). The chemical structures of all compounds were determined by extensive spectroscopic and spectrometric analysis. Methylation of 2 using TMS-diazomethane afforded 1, which unequivocally established that both 1 and 2 possessed a 10-methyl-2H-pyrano[2,3-f]quinolin-2-one skeleton. These pyridocoumarin alkaloids are putatively proposed to arise biosynthetically from an aporphinoid precursor. Compounds 1-10 were evaluated for in vitro antimalarial activity against a chloroquine-sensitive Plasmodium falciparum line (3D7). Sauristolactam (6) and (-)-anonaine (7) exhibited the most potent antiparasitic activity with IC(50) values of 9 and 7 muM, respectively.
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