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Aristolactam AII

CAS# 53948-07-5

Aristolactam AII

Catalog No. BCN3924----Order now to get a substantial discount!

Product Name & Size Price Stock
Aristolactam AII: 5mg $828 In Stock
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Quality Control of Aristolactam AII

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Chemical structure

Aristolactam AII

3D structure

Chemical Properties of Aristolactam AII

Cas No. 53948-07-5 SDF Download SDF
PubChem ID 148657 Appearance Yellow powder
Formula C16H11NO3 M.Wt 265.3
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES COC1=C(C=C2C3=C1C4=CC=CC=C4C=C3NC2=O)O
Standard InChIKey ZEKAIRFOYPDZNC-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Aristolactam AII

The herbs of Aristolochia debilis Sieb. et Zucc

Biological Activity of Aristolactam AII

Description1. Aristolactam AII has cytotoxic activity. 2. Aristolactam AII shows platelet aggregation inhibitory activity.
TargetsPAFR

Aristolactam AII Dilution Calculator

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Aristolactam AII Molarity Calculator

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Preparing Stock Solutions of Aristolactam AII

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7693 mL 18.8466 mL 37.6932 mL 75.3864 mL 94.2329 mL
5 mM 0.7539 mL 3.7693 mL 7.5386 mL 15.0773 mL 18.8466 mL
10 mM 0.3769 mL 1.8847 mL 3.7693 mL 7.5386 mL 9.4233 mL
50 mM 0.0754 mL 0.3769 mL 0.7539 mL 1.5077 mL 1.8847 mL
100 mM 0.0377 mL 0.1885 mL 0.3769 mL 0.7539 mL 0.9423 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Aristolactam AII

Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis.[Pubmed:23158725]

Phytochemistry. 2013 Feb;86:121-6.

Chemical investigation of the CH(2)Cl(2)/CH(3)OH extracts from aerial parts of the Australian plant Goniothalamus australis has resulted in the isolation of two pyridocoumarin alkaloids, goniothalines A (1) and B (2) as well as eight known natural products, Aristolactam AII (3), enterocarpam II (4), caldensine (5), sauristolactam (6), (-)-anonaine (7), asimilobine (8), altholactone (9) and (+)-goniofufurone (10). The chemical structures of all compounds were determined by extensive spectroscopic and spectrometric analysis. Methylation of 2 using TMS-diazomethane afforded 1, which unequivocally established that both 1 and 2 possessed a 10-methyl-2H-pyrano[2,3-f]quinolin-2-one skeleton. These pyridocoumarin alkaloids are putatively proposed to arise biosynthetically from an aporphinoid precursor. Compounds 1-10 were evaluated for in vitro antimalarial activity against a chloroquine-sensitive Plasmodium falciparum line (3D7). Sauristolactam (6) and (-)-anonaine (7) exhibited the most potent antiparasitic activity with IC(50) values of 9 and 7 muM, respectively.

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