EuparoneCAS# 53947-86-7 |
Quality Control & MSDS
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Number of papers citing our products
| Cas No. | 53947-86-7 | SDF | Download SDF |
| PubChem ID | 104654 | Appearance | Powder |
| Formula | C12H10O4 | M.Wt | 218.20 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-(5-acetyl-6-hydroxy-1-benzofuran-2-yl)ethanone | ||
| SMILES | CC(=O)C1=CC2=CC(=C(C=C2O1)O)C(=O)C | ||
| Standard InChIKey | FOXRXAILTBHLQA-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C12H10O4/c1-6(13)9-3-8-4-11(7(2)14)16-12(8)5-10(9)15/h3-5,15H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Eupatarone is a natural product from Eupatorium sternbergianum. |
| In vitro | Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): further biological activities and constituents.[Pubmed: 11746861]Phytother Res. 2001 Dec;15(8):687-90.
Previous reports from this laboratory revealed that cistifolin from the antirheumatic herbal drug, gravel root (rhizome of Eupatorium purpureum), showed activity both in in vitro and in vivo models of inflammation.
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Euparone Dilution Calculator
Euparone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.583 mL | 22.9148 mL | 45.8295 mL | 91.659 mL | 114.5738 mL |
| 5 mM | 0.9166 mL | 4.583 mL | 9.1659 mL | 18.3318 mL | 22.9148 mL |
| 10 mM | 0.4583 mL | 2.2915 mL | 4.583 mL | 9.1659 mL | 11.4574 mL |
| 50 mM | 0.0917 mL | 0.4583 mL | 0.9166 mL | 1.8332 mL | 2.2915 mL |
| 100 mM | 0.0458 mL | 0.2291 mL | 0.4583 mL | 0.9166 mL | 1.1457 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): further biological activities and constituents.[Pubmed:11746861]
Phytother Res. 2001 Dec;15(8):687-90.
Previous reports from this laboratory revealed that cistifolin from the antirheumatic herbal drug, gravel root (rhizome of Eupatorium purpureum), showed activity both in in vitro and in vivo models of inflammation. Data are now presented to show that, in addition to the LFA-1 and other integrin-mediated leucocyte adhesions, cistifolin inhibits the Mac-1 (CD11b/CD18)-dependent monocyte adhesion to fibrinogen in a concentration-dependent manner. Further phytochemical analysis of the crude extract also led to the isolation of three known benzofurans, euparin, Euparone, 6-hydroxy-3beta-methoxytrematone and a new benzofuran, 5-acetyl-6-hydroxy-2-(1-oxo-2-acetoxy-ethyl)-benzofuran. None of these compounds were active in suppressing integrin-mediated monocytic U937 cell adhesions in vitro.
