Euparone

CAS# 53947-86-7

Euparone

Catalog No. BCN7204----Order now to get a substantial discount!

Product Name & Size Price Stock
Euparone: 5mg $615 In Stock
Euparone: 10mg Please Inquire In Stock
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Quality Control of Euparone

Number of papers citing our products

Chemical structure

Euparone

3D structure

Chemical Properties of Euparone

Cas No. 53947-86-7 SDF Download SDF
PubChem ID 104654 Appearance Powder
Formula C12H10O4 M.Wt 218.20
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-(5-acetyl-6-hydroxy-1-benzofuran-2-yl)ethanone
SMILES CC(=O)C1=CC2=CC(=C(C=C2O1)O)C(=O)C
Standard InChIKey FOXRXAILTBHLQA-UHFFFAOYSA-N
Standard InChI InChI=1S/C12H10O4/c1-6(13)9-3-8-4-11(7(2)14)16-12(8)5-10(9)15/h3-5,15H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Euparone

The rhizomes of Eupatorium purpureum.

Biological Activity of Euparone

DescriptionEupatarone is a natural product from Eupatorium sternbergianum.
In vitro

Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): further biological activities and constituents.[Pubmed: 11746861]

Phytother Res. 2001 Dec;15(8):687-90.

Previous reports from this laboratory revealed that cistifolin from the antirheumatic herbal drug, gravel root (rhizome of Eupatorium purpureum), showed activity both in in vitro and in vivo models of inflammation.
METHODS AND RESULTS:
Data are now presented to show that, in addition to the LFA-1 and other integrin-mediated leucocyte adhesions, cistifolin inhibits the Mac-1 (CD11b/CD18)-dependent monocyte adhesion to fibrinogen in a concentration-dependent manner. Further phytochemical analysis of the crude extract also led to the isolation of three known benzofurans, euparin, Euparone, 6-hydroxy-3beta-methoxytrematone and a new benzofuran, 5-acetyl-6-hydroxy-2-(1-oxo-2-acetoxy-ethyl)-benzofuran.
CONCLUSIONS:
None of these compounds were active in suppressing integrin-mediated monocytic U937 cell adhesions in vitro.

Euparone Dilution Calculator

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Euparone Molarity Calculator

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Preparing Stock Solutions of Euparone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.583 mL 22.9148 mL 45.8295 mL 91.659 mL 114.5738 mL
5 mM 0.9166 mL 4.583 mL 9.1659 mL 18.3318 mL 22.9148 mL
10 mM 0.4583 mL 2.2915 mL 4.583 mL 9.1659 mL 11.4574 mL
50 mM 0.0917 mL 0.4583 mL 0.9166 mL 1.8332 mL 2.2915 mL
100 mM 0.0458 mL 0.2291 mL 0.4583 mL 0.9166 mL 1.1457 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Euparone

Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): further biological activities and constituents.[Pubmed:11746861]

Phytother Res. 2001 Dec;15(8):687-90.

Previous reports from this laboratory revealed that cistifolin from the antirheumatic herbal drug, gravel root (rhizome of Eupatorium purpureum), showed activity both in in vitro and in vivo models of inflammation. Data are now presented to show that, in addition to the LFA-1 and other integrin-mediated leucocyte adhesions, cistifolin inhibits the Mac-1 (CD11b/CD18)-dependent monocyte adhesion to fibrinogen in a concentration-dependent manner. Further phytochemical analysis of the crude extract also led to the isolation of three known benzofurans, euparin, Euparone, 6-hydroxy-3beta-methoxytrematone and a new benzofuran, 5-acetyl-6-hydroxy-2-(1-oxo-2-acetoxy-ethyl)-benzofuran. None of these compounds were active in suppressing integrin-mediated monocytic U937 cell adhesions in vitro.

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