Arnicolide C

CAS# 34532-67-7

Arnicolide C

Catalog No. BCN7978----Order now to get a substantial discount!

Product Name & Size Price Stock
Arnicolide C: 5mg $299 In Stock
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Quality Control of Arnicolide C

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Chemical structure

Arnicolide C

3D structure

Chemical Properties of Arnicolide C

Cas No. 34532-67-7 SDF Download SDF
PubChem ID 14656910 Appearance Powder
Formula C19H26O5 M.Wt 334.41
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] 2-methylpropanoate
SMILES CC1CC2C(C(C(=O)O2)C)C(C3(C1C=CC3=O)C)OC(=O)C(C)C
Standard InChIKey WKUOPGZYLRFCHJ-APDQSUQKSA-N
Standard InChI InChI=1S/C19H26O5/c1-9(2)17(21)24-16-15-11(4)18(22)23-13(15)8-10(3)12-6-7-14(20)19(12,16)5/h6-7,9-13,15-16H,8H2,1-5H3/t10-,11+,12+,13-,15-,16+,19+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Arnicolide C

The herbs of Centipeda minima

Biological Activity of Arnicolide C

Description1. Arnicolide C exhibits significant antiallergy activity.

Arnicolide C Dilution Calculator

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Arnicolide C Molarity Calculator

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Preparing Stock Solutions of Arnicolide C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9903 mL 14.9517 mL 29.9034 mL 59.8068 mL 74.7585 mL
5 mM 0.5981 mL 2.9903 mL 5.9807 mL 11.9614 mL 14.9517 mL
10 mM 0.299 mL 1.4952 mL 2.9903 mL 5.9807 mL 7.4759 mL
50 mM 0.0598 mL 0.299 mL 0.5981 mL 1.1961 mL 1.4952 mL
100 mM 0.0299 mL 0.1495 mL 0.299 mL 0.5981 mL 0.7476 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Arnicolide C

[Chemical constituents from Centipeda minima].[Pubmed:19777837]

Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(12):1520-2.

OBJECTIVE: To study the chemical constituents from Centipeda minima. METHOD: The constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and HPLC-ODS, and identified by spectroscopic methods. RESULT: Ten compounds, (-)-cis-chrysanthenol-O-beta-D-glucopyranoside (1), methy 3,5-dicaffeoylquinate (2), 3,5-di-O-caffeoyl quinicacid (3), tricin (4), 2-amino-4-methyl-pentanoicacid (5), 2-amino-3-phenyl-propionic acid (6), 4-amino-4-carboxychroman-2-one (7), brevilin-A (8), Arnicolide C (9), arnicolide D (10) were isolated and identified. CONCLUSION: Compounds 1-7 were isolated from the plant for the first time.

Description

ArnicolideC is a sesquiterpene lactone isolated Centipeda minima. ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation.

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