AxillarineCAS# 19637-66-2 |
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| Cas No. | 19637-66-2 | SDF | Download SDF |
| PubChem ID | 309285 | Appearance | Cryst. |
| Formula | C18H27NO7 | M.Wt | 369.41 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC(C)C1C(C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C(C)O)O)O | ||
| Standard InChIKey | JGQRXNDIMGIXDT-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Structure Identification | Phytochemistry,1985,24,(2):376–378.Pyrrolizidine alkaloids from seeds of Crotalaria scassellatii[Reference: WebLink]
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Axillarine Dilution Calculator
Axillarine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.707 mL | 13.5351 mL | 27.0702 mL | 54.1404 mL | 67.6755 mL |
| 5 mM | 0.5414 mL | 2.707 mL | 5.414 mL | 10.8281 mL | 13.5351 mL |
| 10 mM | 0.2707 mL | 1.3535 mL | 2.707 mL | 5.414 mL | 6.7675 mL |
| 50 mM | 0.0541 mL | 0.2707 mL | 0.5414 mL | 1.0828 mL | 1.3535 mL |
| 100 mM | 0.0271 mL | 0.1354 mL | 0.2707 mL | 0.5414 mL | 0.6768 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Generation and characterization of monoclonal antibodies against the pyrrolizidine alkaloid retrorsine.[Pubmed:9581524]
Planta Med. 1998 Apr;64(3):259-63.
Monoclonal antibodies against retrorsine were established using a retrorsine-hemisuccinate::bovine-thyroglobuline conjugate as antigen for immunization. In competitive enzyme-linked immunoassays the specificity of the obtained antibodies was tested with 20 different pyrrolizidine alkaloids. Among these the alkaloids acetylgynuramine, gynuramine, integerrimine, neoplatyphylline, platyphylline, rosmarinine, senecionine, and seneciphylline were able to bind the antibody. There was no cross-reactivity with the alkaloids senkirkine, angeloyl-heliotridine, heliotridine, Axillarine, anacrotine, monocrotaline, madurensine, otosenine, retronecine, tussilagine, triangularine, and jacoline as well as with seneciphylline N-oxide. From this antigen spectrum it can be concluded that besides the necic structure itself the dominant and discriminative epitope consists of the exocyclic ethylidene group of the various diesters.
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