Calcium pantothenateCAS# 137-08-6 |
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| Cas No. | 137-08-6 | SDF | Download SDF |
| PubChem ID | 443753 | Appearance | White crystalline powder |
| Formula | C18H32CaN2O10 | M.Wt | 476.54 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | Calcium D-pantothenate; Vitamin B5 calcium salt; Calcium pantothenate | ||
| Solubility | H2O : ≥ 200 mg/mL (839.38 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | calcium;3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoate | ||
| SMILES | CC(C)(CO)C(C(=O)NCCC(=O)[O-])O.CC(C)(CO)C(C(=O)NCCC(=O)[O-])O.[Ca+2] | ||
| Standard InChIKey | FAPWYRCQGJNNSJ-UBKPKTQASA-L | ||
| Standard InChI | InChI=1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Calcium pantothenate Dilution Calculator
Calcium pantothenate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0985 mL | 10.4923 mL | 20.9846 mL | 41.9692 mL | 52.4615 mL |
| 5 mM | 0.4197 mL | 2.0985 mL | 4.1969 mL | 8.3938 mL | 10.4923 mL |
| 10 mM | 0.2098 mL | 1.0492 mL | 2.0985 mL | 4.1969 mL | 5.2461 mL |
| 50 mM | 0.042 mL | 0.2098 mL | 0.4197 mL | 0.8394 mL | 1.0492 mL |
| 100 mM | 0.021 mL | 0.1049 mL | 0.2098 mL | 0.4197 mL | 0.5246 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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D-Pantothenic acid hemicalcium salt, a kind of water soluble vitamin, can reduce the patulin content of the apple juice. IC50 value: Target: In vitro: In human dermal fibroblasts from three different donors, D-Pantothenic acid hemicalcium salt accelerates the wound healing process by increasing the number of migrating cells, their distance and hence their speed. In addition, cell division is increased and the protein synthesis changed [1]. In vivo:
References:
[1]. Weimann BI, et al. Studies on wound healing: effects of calcium D-pantothenate on the migration, proliferation and protein synthesis of human dermal fibroblasts in culture. Int J Vitam Nutr Res. 1999 Mar;69(2):113-9.
[2]. Serafettin Yazici, et al. Effect of thiamine hydrochloride, pyridoxine hydrochloride and calcium-d-pantothenate on the patulin content of apple juice concentrate. Food / Nahrung
Volume 46, Issue 4, pages 256–257, 1 July 2002
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Profiles of Streptococcus thermophilus MN-ZLW-002 nutrient requirements in controlled pH batch fermentations.[Pubmed:29682906]
Microbiologyopen. 2019 Feb;8(2):e00633.
This study aimed to evaluate the profiles of Streptococcus thermophilus nutrient requirements to guide the design of media for high cell density culturing. The growth kinetics, physiological state, and nutrient requirement profiles of S. thermophilus were analyzed in chemically defined media. The results showed that the intracellular ATP concentration, H(+) -ATPase activity, NADH/NAD(+) , and NH3 concentrations varied with intracellular pH. The nutrient components with the highest amounts required were Leu and Asp; ascorbic acid and p-amino benzoic acid; K(+) and PO4 (3-) ; and guanine and uracil. The nutrient components with the largest required ratios were Arg, His, and Met; folic acid, cyanocobalamine, biotin, and nicotinic acid; Ca(2+) and Mg(2+) ; and guanine and uracil. In this study, different nutrient components were primarily used at different phase. Trp, Tyr, Calcium pantothenate, thiamine, guanine, and Mg(2+) were mainly used from late-lag to midexponential phase. Met, Pro, Phe, Ala, Gly, nicotinic acid, and riboflavin were mainly used from midexponential to late-exponential phase. The highest bioavailabilities of nutrient components were also found at diverse phase. Met, Leu, Ile, Asn, Glu, Lys, Pro, Gly, riboflavin, nicotinic acid, adenine, uracil, inosine, and Ca(2+) had the highest bioavailability from late-lag to midexponential phase. Lactose, Glu, Asp, His, Trp, Cys, Val, Arg, Phe, Ala, Ser, Thr, Tyr, folate and cobalamin, Calcium pantothenate, ascorbic acid, thiamine, biotin, p-amino benzoic acid, vitamin B6 , K(+) , Mg(2+) , guanine, xanthine, and PO4 (3-) had the highest bioavailability from midexponential to late-exponential phase. This study elucidated the nutrient requirement profiles with culture time and biomass at various average growth rates during the growth of S. thermophilus. The present results will help to formulate complex media for high cell density cultivation and provide the theoretical basis for S. thermophilus feeding strategies.
