CernuineCAS# 6880-84-8 |
Quality Control & MSDS
Number of papers citing our products
![](/media/diy/images/number_cite.png)
Chemical structure
![Cernuine](/media/images/struct/BCN9617.png)
3D structure
Cas No. | 6880-84-8 | SDF | Download SDF |
PubChem ID | 442472 | Appearance | Oil |
Formula | C16H26N2O | M.Wt | 262.39 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | (1S,7S,9R,11S,13S)-11-methyl-2,17-diazatetracyclo[7.7.1.02,7.013,17]heptadecan-3-one | ||
SMILES | CC1CC2CCCC3N2C(C1)CC4N3C(=O)CCC4 | ||
Standard InChIKey | IWSJXTCXZSUCNS-LXFSFDBISA-N | ||
Standard InChI | InChI=1S/C16H26N2O/c1-11-8-12-4-2-6-15-17(12)14(9-11)10-13-5-3-7-16(19)18(13)15/h11-15H,2-10H2,1H3/t11-,12-,13-,14+,15-/m0/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
![](/statics/images/closeICO.png)
Cernuine Dilution Calculator
![](/statics/images/closeICO.png)
Cernuine Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.8111 mL | 19.0556 mL | 38.1112 mL | 76.2224 mL | 95.278 mL |
5 mM | 0.7622 mL | 3.8111 mL | 7.6222 mL | 15.2445 mL | 19.0556 mL |
10 mM | 0.3811 mL | 1.9056 mL | 3.8111 mL | 7.6222 mL | 9.5278 mL |
50 mM | 0.0762 mL | 0.3811 mL | 0.7622 mL | 1.5244 mL | 1.9056 mL |
100 mM | 0.0381 mL | 0.1906 mL | 0.3811 mL | 0.7622 mL | 0.9528 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
![](/media/diy/images/pphome/Calcutta University.jpg)
Calcutta University
![](/media/diy/images/pphome/University of Minnesota.jpg)
University of Minnesota
![](/media/diy/images/pphome/University of Maryland School of Medicine.jpg)
University of Maryland School of Medicine
![](/media/diy/images/pphome/University of Illinois at Chicago.jpg)
University of Illinois at Chicago
![](/media/diy/images/pphome/The Ohio State University.jpg)
The Ohio State University
![](/media/diy/images/pphome/University of Zurich.jpg)
University of Zurich
![](/media/diy/images/pphome/Harvard University.jpg)
Harvard University
![](/media/diy/images/pphome/Colorado State University.jpg)
Colorado State University
![](/media/diy/images/pphome/Auburn University.jpg)
Auburn University
![](/media/diy/images/pphome/Yale University.jpg)
Yale University
![](/media/diy/images/pphome/Worcester Polytechnic Institute.jpg)
Worcester Polytechnic Institute
![](/media/diy/images/pphome/Washington State University.jpg)
Washington State University
![](/media/diy/images/pphome/Stanford University.jpg)
Stanford University
![](/media/diy/images/pphome/University of Leipzig.jpg)
University of Leipzig
![](/media/diy/images/pphome/Universidade da Beira Interior.jpg)
Universidade da Beira Interior
![](/media/diy/images/pphome/The Institute of Cancer Research.jpg)
The Institute of Cancer Research
![](/media/diy/images/pphome/Heidelberg University.jpg)
Heidelberg University
![](/media/diy/images/pphome/University of Amsterdam.jpg)
University of Amsterdam
![](/media/diy/images/pphome/University of Auckland.jpg)
University of Auckland
![TsingHua University](/media/diy/images/pphome/TsingHua University.jpg)
TsingHua University
![The University of Michigan](/media/diy/images/pphome/University of Michigan.jpg)
The University of Michigan
![Miami University](/media/diy/images/pphome/Miami University.jpg)
Miami University
![DRURY University](/media/diy/images/pphome/DRURY University.jpg)
DRURY University
![Jilin University](/media/diy/images/pphome/Jilin University.jpg)
Jilin University
![Fudan University](/media/diy/images/pphome/Fudan University.jpg)
Fudan University
![Wuhan University](/media/diy/images/pphome/Wuhan University.jpg)
Wuhan University
![Sun Yat-sen University](/media/diy/images/pphome/Sun Yat-sen University.jpg)
Sun Yat-sen University
![Universite de Paris](/media/diy/images/pphome/Universite de Paris.jpg)
Universite de Paris
![Deemed University](/media/diy/images/pphome/Deemed University.jpg)
Deemed University
![Auckland University](/media/diy/images/pphome/Auckland University.jpg)
Auckland University
![The University of Tokyo](/media/diy/images/pphome/Tokyo University.jpg)
The University of Tokyo
![Korea University](/media/diy/images/pphome/Korea University.jpg)
Korea University
- Greveichromenol
Catalog No.:BCN9616
CAS No.:35930-29-1
- Tuberculatin
Catalog No.:BCN9615
CAS No.:90706-10-8
- Illiciumlignan D
Catalog No.:BCN9614
CAS No.:2237239-36-8
- 6,7-Di-O-acetylsinococuline
Catalog No.:BCN9613
CAS No.:1054312-81-0
- Taiwanin E
Catalog No.:BCN9612
CAS No.:22743-05-1
- 5-Methoxyjusticidin A
Catalog No.:BCN9611
CAS No.:205505-62-0
- 3-O-(p-Hydroxybenzoyl)serratriol
Catalog No.:BCN9610
CAS No.:1448534-93-7
- Karavilagenin F
Catalog No.:BCN9609
CAS No.:1639024-15-9
- Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
Catalog No.:BCN9608
CAS No.:1448779-19-8
- Beiwutine
Catalog No.:BCN9607
CAS No.:76918-93-9
- Taiwanin C
Catalog No.:BCN9606
CAS No.:14944-34-4
- Stepharine
Catalog No.:BCN9605
CAS No.:2810-21-1
- Karavilagenin B
Catalog No.:BCN9618
CAS No.:912329-02-3
- Heteropeucenin 7-methyl ether
Catalog No.:BCN9619
CAS No.:26213-95-6
- Alloptaeroxylin
Catalog No.:BCN9620
CAS No.:4670-29-5
- 7α-O-Ethylmorroniside
Catalog No.:BCN9621
CAS No.:1116650-29-3
- O-Methylalloptaeroxylin
Catalog No.:BCN9622
CAS No.:35930-31-5
- 16-Oxo-21-episerratenediol
Catalog No.:BCN9623
CAS No.:1194739-51-9
- Umtatin
Catalog No.:BCN9624
CAS No.:17398-06-0
- Dihydrodehydrodiconiferyl Alcohol Beta-D-Xylopyranoside
Catalog No.:BCN9625
CAS No.:1048996-18-4
- Neochlorogenin
Catalog No.:BCN9626
CAS No.:511-91-1
- (S)-4-Methoxydalbergione
Catalog No.:BCN9627
CAS No.:2543-95-5
- Lutonarin
Catalog No.:BCN9628
CAS No.:35450-86-3
- Pedaliin
Catalog No.:BCN9629
CAS No.:22860-72-6
A neuroinformatics study to compare inhibition efficiency of three natural ligands (Fawcettimine, Cernuine and Lycodine) against human brain acetylcholinesterase.[Pubmed:25611730]
Network. 2015;26(1):25-34.
Enzyme-inhibition is considered as a potent therapeutic approach to the treatment of diseases associated with acetylcholinesterase (AChE). The present study elucidates molecular interactions of human brain AChE, with three natural ligands Lycodine, Cernuine and Fawcettimine for comparison. Docking between these ligands and enzyme was performed using 'Autodock 4.2'. It was determined that polar and hydrophobic interactions play an important role in the correct positioning of Lycodine, Cernuine and Fawcettimine within the 'catalytic site' of AChE to permit docking. This approach would be helpful to understand the selectivity of the given drug molecule in the treatment of neurological disorder. Moreover, the present study confirms that Lycodine is a more efficient inhibitor of human brain AChE compared to Cernuine and Fawcettimine with reference to DeltaG and Ki values.
Lycopodium alkaloids: isolation and asymmetric synthesis.[Pubmed:21452079]
Top Curr Chem. 2012;309:1-31.
Lycopodium alkaloids have attracted the attention of many natural product chemists and synthetic organic chemists due to their important biological activities and unique skeletal characteristics. In this review we describe isolation and asymmetric syntheses of several new alkaloids such as lycoposerramines-C, -V, -W, and Cernuine, and show that asymmetric total synthesis played a key role in elucidating the structures of these complex natural products.
First asymmetric total syntheses of cernuane-type Lycopodium alkaloids, cernuine, and cermizine D.[Pubmed:18429621]
Org Lett. 2008 May 15;10(10):1987-90.
The first total syntheses of two cernuane-type Lycopodium alkaloids, (-)-Cernuine and (+)-cermizine D, were accomplished starting from (+)-citronellal. The syntheses involved organocatalytic alpha-amination to afford oxazolidinone, which is used for diastereoselective allylation, and asymmetric transfer aminoallylation followed by stereoselective construction of an aminal moiety as key steps.