TuberculatinCAS# 90706-10-8 |
Quality Control & MSDS
Number of papers citing our products
![](/media/diy/images/number_cite.png)
Chemical structure
![Tuberculatin](/media/images/struct/BCN9615.png)
3D structure
Cas No. | 90706-10-8 | SDF | Download SDF |
PubChem ID | 101293623 | Appearance | Powder |
Formula | C26H24O11 | M.Wt | 512.5 |
Type of Compound | Lignans | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 9-(1,3-benzodioxol-5-yl)-4-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-6,7-dimethoxy-1H-benzo[f][2]benzofuran-3-one | ||
SMILES | COC1=C(C=C2C(=C1)C(=C3COC(=O)C3=C2OC4C(C(CO4)(CO)O)O)C5=CC6=C(C=C5)OCO6)OC | ||
Standard InChIKey | BJATWCDTYAVIDS-AYRHNUGRSA-N | ||
Standard InChI | InChI=1S/C26H24O11/c1-31-17-6-13-14(7-18(17)32-2)22(37-25-23(28)26(30,9-27)10-34-25)21-15(8-33-24(21)29)20(13)12-3-4-16-19(5-12)36-11-35-16/h3-7,23,25,27-28,30H,8-11H2,1-2H3/t23-,25-,26+/m0/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
![](/statics/images/closeICO.png)
Tuberculatin Dilution Calculator
![](/statics/images/closeICO.png)
Tuberculatin Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.9512 mL | 9.7561 mL | 19.5122 mL | 39.0244 mL | 48.7805 mL |
5 mM | 0.3902 mL | 1.9512 mL | 3.9024 mL | 7.8049 mL | 9.7561 mL |
10 mM | 0.1951 mL | 0.9756 mL | 1.9512 mL | 3.9024 mL | 4.878 mL |
50 mM | 0.039 mL | 0.1951 mL | 0.3902 mL | 0.7805 mL | 0.9756 mL |
100 mM | 0.0195 mL | 0.0976 mL | 0.1951 mL | 0.3902 mL | 0.4878 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
![](/media/diy/images/pphome/Calcutta University.jpg)
Calcutta University
![](/media/diy/images/pphome/University of Minnesota.jpg)
University of Minnesota
![](/media/diy/images/pphome/University of Maryland School of Medicine.jpg)
University of Maryland School of Medicine
![](/media/diy/images/pphome/University of Illinois at Chicago.jpg)
University of Illinois at Chicago
![](/media/diy/images/pphome/The Ohio State University.jpg)
The Ohio State University
![](/media/diy/images/pphome/University of Zurich.jpg)
University of Zurich
![](/media/diy/images/pphome/Harvard University.jpg)
Harvard University
![](/media/diy/images/pphome/Colorado State University.jpg)
Colorado State University
![](/media/diy/images/pphome/Auburn University.jpg)
Auburn University
![](/media/diy/images/pphome/Yale University.jpg)
Yale University
![](/media/diy/images/pphome/Worcester Polytechnic Institute.jpg)
Worcester Polytechnic Institute
![](/media/diy/images/pphome/Washington State University.jpg)
Washington State University
![](/media/diy/images/pphome/Stanford University.jpg)
Stanford University
![](/media/diy/images/pphome/University of Leipzig.jpg)
University of Leipzig
![](/media/diy/images/pphome/Universidade da Beira Interior.jpg)
Universidade da Beira Interior
![](/media/diy/images/pphome/The Institute of Cancer Research.jpg)
The Institute of Cancer Research
![](/media/diy/images/pphome/Heidelberg University.jpg)
Heidelberg University
![](/media/diy/images/pphome/University of Amsterdam.jpg)
University of Amsterdam
![](/media/diy/images/pphome/University of Auckland.jpg)
University of Auckland
![TsingHua University](/media/diy/images/pphome/TsingHua University.jpg)
TsingHua University
![The University of Michigan](/media/diy/images/pphome/University of Michigan.jpg)
The University of Michigan
![Miami University](/media/diy/images/pphome/Miami University.jpg)
Miami University
![DRURY University](/media/diy/images/pphome/DRURY University.jpg)
DRURY University
![Jilin University](/media/diy/images/pphome/Jilin University.jpg)
Jilin University
![Fudan University](/media/diy/images/pphome/Fudan University.jpg)
Fudan University
![Wuhan University](/media/diy/images/pphome/Wuhan University.jpg)
Wuhan University
![Sun Yat-sen University](/media/diy/images/pphome/Sun Yat-sen University.jpg)
Sun Yat-sen University
![Universite de Paris](/media/diy/images/pphome/Universite de Paris.jpg)
Universite de Paris
![Deemed University](/media/diy/images/pphome/Deemed University.jpg)
Deemed University
![Auckland University](/media/diy/images/pphome/Auckland University.jpg)
Auckland University
![The University of Tokyo](/media/diy/images/pphome/Tokyo University.jpg)
The University of Tokyo
![Korea University](/media/diy/images/pphome/Korea University.jpg)
Korea University
- Illiciumlignan D
Catalog No.:BCN9614
CAS No.:2237239-36-8
- 6,7-Di-O-acetylsinococuline
Catalog No.:BCN9613
CAS No.:1054312-81-0
- Taiwanin E
Catalog No.:BCN9612
CAS No.:22743-05-1
- 5-Methoxyjusticidin A
Catalog No.:BCN9611
CAS No.:205505-62-0
- 3-O-(p-Hydroxybenzoyl)serratriol
Catalog No.:BCN9610
CAS No.:1448534-93-7
- Karavilagenin F
Catalog No.:BCN9609
CAS No.:1639024-15-9
- Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
Catalog No.:BCN9608
CAS No.:1448779-19-8
- Beiwutine
Catalog No.:BCN9607
CAS No.:76918-93-9
- Taiwanin C
Catalog No.:BCN9606
CAS No.:14944-34-4
- Stepharine
Catalog No.:BCN9605
CAS No.:2810-21-1
- 7,7'-Dihydrotaiwanin C
Catalog No.:BCN9604
CAS No.:216955-79-2
- Menisdaurilide
Catalog No.:BCN9603
CAS No.:67765-59-7
- Greveichromenol
Catalog No.:BCN9616
CAS No.:35930-29-1
- Cernuine
Catalog No.:BCN9617
CAS No.:6880-84-8
- Karavilagenin B
Catalog No.:BCN9618
CAS No.:912329-02-3
- Heteropeucenin 7-methyl ether
Catalog No.:BCN9619
CAS No.:26213-95-6
- Alloptaeroxylin
Catalog No.:BCN9620
CAS No.:4670-29-5
- 7α-O-Ethylmorroniside
Catalog No.:BCN9621
CAS No.:1116650-29-3
- O-Methylalloptaeroxylin
Catalog No.:BCN9622
CAS No.:35930-31-5
- 16-Oxo-21-episerratenediol
Catalog No.:BCN9623
CAS No.:1194739-51-9
- Umtatin
Catalog No.:BCN9624
CAS No.:17398-06-0
- Dihydrodehydrodiconiferyl Alcohol Beta-D-Xylopyranoside
Catalog No.:BCN9625
CAS No.:1048996-18-4
- Neochlorogenin
Catalog No.:BCN9626
CAS No.:511-91-1
- (S)-4-Methoxydalbergione
Catalog No.:BCN9627
CAS No.:2543-95-5
DNA strand-scission by phloroglucinols and lignans from heartwood of Garcinia subelliptica Merr. and Justicia plants.[Pubmed:17686498]
Phytochemistry. 2008 Jan;69(1):225-33.
Five 2,4,6-prenylated phloroglucinols, garcinielliptones HA (1), HB (2), HC (3), HD (4) and HE (5), were isolated from the heartwood of Garcinia subelliptica Merr. Their structures, including relative configurations, were elucidated by means of spectroscopic data analysis. The ability of phloroglucinols, 1-5 and lignans, Tuberculatin (8), justicidin A (9), procumbenoside A (10) and ciliatosides A (11) and B (12), isolated from Justicia ciliata and Justicia procumbens, to induce DNA-cleavage activity was examined using pBR322, a supercoiled, covalently closed circular DNA, and it was analyzed by agarose gel electrophoresis. In the presence of Cu (II), compounds 3, 8, 10 and 11 caused significant breakage of supercoiled plasmid pBR322. The products were relaxed circles with no detectable linear forms. In the Cu(II)-mediated DNA damage of 3 and selective compound 8, Cu(I) was shown not to be an essential intermediate by using the Cu(I)-specific sequestering reagent neocuproine.
Cytotoxic arylnaphthalene lignans from a Vietnamese acanthaceae, Justicia patentiflora.[Pubmed:15921419]
J Nat Prod. 2005 May;68(5):734-8.
One new norlignan (1) and five new lignans (2-6) were isolated from the leaves and stems of Justicia patentiflora by a bioassay-guided purification. Five known compounds, carinatone, diphyllin, justicidin A, taiwanin E, and Tuberculatin, were also found in J. patentiflora. Most of the new compounds display significant activity in in vitro cytotoxic assays against KB, HCT116, and MCF-7 cancer cell lines and arrest the cell cycle in the G0/G1 phase.
Patavine, a new arylnaphthalene lignan glycoside from shoot cultures of Haplophyllum patavinum.[Pubmed:12045345]
Chem Pharm Bull (Tokyo). 2002 Jun;50(6):844-6.
A new arylnaphthalene lignan glycoside, patavine (1), together with five known lignans, justicidin B (2), diphyllin (3), Tuberculatin (4), majidine (5), and arabelline (6) were isolated from shoot cultures of Haplophyllum patavinum. The structure of the new compound was elucidated by extensive one-dimensional (1D) and two-dimensional (2D) NMR experiments and mass spectrometry. The cytotoxicity of compounds 1, and 3-6 against LoVo human colon carcinoma cells was investigated.
Potent cytotoxic lignans from Justicia procumbens and their effects on nitric oxide and tumor necrosis factor-alpha production in mouse macrophages.[Pubmed:11908984]
J Nat Prod. 2002 Mar;65(3):379-81.
A new lignan glycoside, 4-O-alpha-L-arabinopyranosyl-(1' "-->2' ')-beta-D-apiofuranosyldiphyllin (2), named procumbenoside A, and 11 known compounds were isolated from the whole plant of Justicia procumbens. The structure of 2 was established by spectral analysis and chemical methods. The known compounds justicidin A (1), diphyllin (3), and Tuberculatin (4) showed potent cytotoxic effects against a number of cancer cells in vitro. Compounds 1 and 4 also strongly enhanced tumor-necrosis factor-alpha (TNF-alpha) generation from mouse macrophage-like RAW 264.7 cells stimulated with lipopolysaccharide (LPS).