CratoxyloneCAS# 149155-01-1 |
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| Cas No. | 149155-01-1 | SDF | Download SDF |
| PubChem ID | 102004659 | Appearance | Yellow powder |
| Formula | C24H28O7 | M.Wt | 428.5 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,3,6-trihydroxy-2-(3-hydroxy-3-methylbutyl)-7-methoxy-8-(3-methylbut-2-enyl)xanthen-9-one | ||
| SMILES | CC(=CCC1=C2C(=CC(=C1OC)O)OC3=CC(=C(C(=C3C2=O)O)CCC(C)(C)O)O)C | ||
| Standard InChIKey | JSXIWUDODLMCGG-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C24H28O7/c1-12(2)6-7-14-19-17(11-16(26)23(14)30-5)31-18-10-15(25)13(8-9-24(3,4)29)21(27)20(18)22(19)28/h6,10-11,25-27,29H,7-9H2,1-5H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The fruits of Garcinia mangostana
| Description | 1. Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC₅₀ value belows 3 uM. |
| Targets | Antifection |
Cratoxylone Dilution Calculator
Cratoxylone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3337 mL | 11.6686 mL | 23.3372 mL | 46.6744 mL | 58.3431 mL |
| 5 mM | 0.4667 mL | 2.3337 mL | 4.6674 mL | 9.3349 mL | 11.6686 mL |
| 10 mM | 0.2334 mL | 1.1669 mL | 2.3337 mL | 4.6674 mL | 5.8343 mL |
| 50 mM | 0.0467 mL | 0.2334 mL | 0.4667 mL | 0.9335 mL | 1.1669 mL |
| 100 mM | 0.0233 mL | 0.1167 mL | 0.2334 mL | 0.4667 mL | 0.5834 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea.[Pubmed:20927694]
Planta Med. 2011 Mar;77(4):377-9.
Bioassay-guided fractionation of the fruit pericarp of Pentadesma butyracea, using the antiplasmodial test, led to the isolation of a new xanthone, named pentadexanthone (1), together with six known compounds: Cratoxylone (2), alpha-mangostin (3), 1,3,5-trihydroxy-2-methoxyxanthone (4), garcinone E (5), (-)-epicathechin (6), and lupeol (7). The structure of 1 was elucidated by spectroscopic data analysis. An antiplasmodial assay was performed with the isolates, in which compounds 1- 3 and 5 exhibited potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC(5)(0) values below 3 microM.
Cratoxylone, isolated from the bark of Cratoxylum Cochinchinense, possesses antiplasmodial activity.
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