Crovatin

CAS# 142409-09-4

Crovatin

Catalog No. BCN2517----Order now to get a substantial discount!

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Crovatin: 5mg $541 In Stock
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Quality Control of Crovatin

Number of papers citing our products

Chemical structure

Crovatin

3D structure

Chemical Properties of Crovatin

Cas No. 142409-09-4 SDF Download SDF
PubChem ID 495412 Appearance Cryst.
Formula C21H26O6 M.Wt 374.43
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name methyl 7-(furan-3-yl)-4-methyl-8,10,12-trioxapentacyclo[11.3.1.01,11.05,9.05,16]heptadecane-17-carboxylate
SMILES CC1CCC23C4C15CC(OC5OC2OC(C3C(=O)OC)CC4)C6=COC=C6
Standard InChIKey GRJSIUBKDJRQIL-UHFFFAOYSA-N
Standard InChI InChI=1S/C21H26O6/c1-11-5-7-20-15-4-3-13(16(20)17(22)23-2)25-18(20)27-19-21(11,15)9-14(26-19)12-6-8-24-10-12/h6,8,10-11,13-16,18-19H,3-5,7,9H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Crovatin

The herbs of Croton caudatus Geisel.var.tomentosus Hook

Protocol of Crovatin

Structure Identification
Planta Med. 2002 Mar;68(3):274-7.

Croblongifolin, a new anticancer clerodane from Croton oblongifolius.[Pubmed: 11914970]


METHODS AND RESULTS:
A new furoclerodane, croblongifolin, together with one known clerodane, Crovatin and one known labdane, nidorellol, were isolated from the stem bark of Croton oblongifolius. Structures were established based on spectroscopic and X-ray analysis.
CONCLUSIONS:
Croblongifolin showed a significant cytotoxicity against various human tumor cell lines including HEP-G2, SW620, CHAGO, KATO3 and BT474.

Crovatin Dilution Calculator

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Crovatin Molarity Calculator

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Preparing Stock Solutions of Crovatin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6707 mL 13.3536 mL 26.7073 mL 53.4145 mL 66.7682 mL
5 mM 0.5341 mL 2.6707 mL 5.3415 mL 10.6829 mL 13.3536 mL
10 mM 0.2671 mL 1.3354 mL 2.6707 mL 5.3415 mL 6.6768 mL
50 mM 0.0534 mL 0.2671 mL 0.5341 mL 1.0683 mL 1.3354 mL
100 mM 0.0267 mL 0.1335 mL 0.2671 mL 0.5341 mL 0.6677 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Crovatin

Croblongifolin, a new anticancer clerodane from Croton oblongifolius.[Pubmed:11914970]

Planta Med. 2002 Mar;68(3):274-7.

A new furoclerodane, croblongifolin, together with one known clerodane, Crovatin and one known labdane, nidorellol, were isolated from the stem bark of Croton oblongifolius. Structures were established based on spectroscopic and X-ray analysis. Croblongifolin showed a significant cytotoxicity against various human tumor cell lines including HEP-G2, SW620, CHAGO, KATO3 and BT474.

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