Glyasperin A

CAS# 142474-52-0

Glyasperin A

Catalog No. BCN6228----Order now to get a substantial discount!

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Glyasperin A: 5mg $903 In Stock
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Quality Control of Glyasperin A

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Chemical structure

Glyasperin A

3D structure

Chemical Properties of Glyasperin A

Cas No. 142474-52-0 SDF Download SDF
PubChem ID 5481963 Appearance Yellow powder
Formula C25H26O6 M.Wt 422.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-6-(3-methylbut-2-enyl)chromen-4-one
SMILES CC(=CCC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)O)CC=C(C)C)O)O)O)C
Standard InChIKey XHCCZOWAHHBCAK-UHFFFAOYSA-N
Standard InChI InChI=1S/C25H26O6/c1-13(2)5-7-15-11-16(8-10-18(15)26)25-24(30)23(29)21-20(31-25)12-19(27)17(22(21)28)9-6-14(3)4/h5-6,8,10-12,26-28,30H,7,9H2,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Glyasperin A

The roots of Glycyrrhiza uralensis Fisch

Biological Activity of Glyasperin A

Description1. Glyasperin A has cytotoxic properties against P-388 cells, its IC50 values being 6.0 microM.

Glyasperin A Dilution Calculator

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Glyasperin A Molarity Calculator

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Preparing Stock Solutions of Glyasperin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3669 mL 11.8343 mL 23.6686 mL 47.3373 mL 59.1716 mL
5 mM 0.4734 mL 2.3669 mL 4.7337 mL 9.4675 mL 11.8343 mL
10 mM 0.2367 mL 1.1834 mL 2.3669 mL 4.7337 mL 5.9172 mL
50 mM 0.0473 mL 0.2367 mL 0.4734 mL 0.9467 mL 1.1834 mL
100 mM 0.0237 mL 0.1183 mL 0.2367 mL 0.4734 mL 0.5917 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Glyasperin A

Macagigantin, a farnesylated flavonol from Macaranga gigantea.[Pubmed:20183255]

J Asian Nat Prod Res. 2009 Nov;11(11):929-32.

A new farnesylated flavonol derivative, macagigantin (1), together with two known flavonoids, Glyasperin A (2) and apigenin (3), had been isolated from the acetone extract of the leaves of Macaranga gigantea. The structure of the new compound was elucidated as 6-farnesylkaempferol based on its spectroscopic data, including UV, IR, 1D and 2D NMR, and HR-EI-MS spectra. Compounds 1-3 were evaluated for their cytotoxic properties against P-388 cells, their IC(50) values being 11.3, 6.0, and 5.1 microM, respectively.

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