Darlingine

CAS# 58471-10-6

Darlingine

Catalog No. BCN1906----Order now to get a substantial discount!

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Quality Control of Darlingine

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Chemical structure

Darlingine

3D structure

Chemical Properties of Darlingine

Cas No. 58471-10-6 SDF Download SDF
PubChem ID 333105 Appearance Needles
Formula C13H17NO2 M.Wt 219.28
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1=C(OC2=C(C1=O)C3CCC(C2)N3C)C
Standard InChIKey WBTZDCUVPGAROE-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H17NO2/c1-7-8(2)16-11-6-9-4-5-10(14(9)3)12(11)13(7)15/h9-10H,4-6H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Protocol of Darlingine

Structure Identification
J Nat Prod. 2000 May;63(5):688-9.

10-Hydroxydarlingine, a new tropane alkaloid from the Australian proteaceous plant triunia erythrocarpa.[Pubmed: 10843590]


METHODS AND RESULTS:
Triunia erythrocarpa was identified as containing alkaloids during chemical screening of Queensland Proteaceae using Dragendorff's reagent. A new tropane, 10-hydroxyDarlingine (1), and the known tropane, Darlingine (2), were isolated from the leaves of T. erythrocarpa.
CONCLUSIONS:
The absolute stereochemistry of 10-hydroxyDarlingine (1) was assigned using the advanced Mosher method. T. erythrocarpa is only the seventh member of the Proteaceae to have been shown to produce alkaloids.

Phytochemistry,1999,52(3):529–531.

Tropane alkaloids from Darlingia darlingiana[Reference: WebLink]


METHODS AND RESULTS:
A new γ-pyranotropane, Darlingine N-oxide, was isolated from the bark and leaves of Darlingia darlingiana, along with the known compound, Darlingine. 1D-NOESY NMR experiments indicated that the N-methyl groups of both alkaloids were orientated towards the pyran ring.

Australian Journal of Chemistry , 1979 , 32 (8) :1827-1840

Alkaloids of Bellendena montana[Reference: WebLink]

Fourteen alkaloids have been isolated from Bellendena montana, a monotypic proteaceous plant endemic in Tasmania.
METHODS AND RESULTS:
The structures of ten of these, bellendine (1), isobellendine (2), Darlingine (3),5,11-dihydroisobellendine (5), 2,3-dihydrobellendine (6), 2,3-epidihydrobellendine (7), 2,3-dihydroDarlingine(8), 3α-acetoxy-6β-isobutoxytropane (9), 6β-acetoxy-3α-isobutoxytropane (10) and 3α-acetoxy-6β-hydroxytropane (11), have been established.

Darlingine Dilution Calculator

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Darlingine Molarity Calculator

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Preparing Stock Solutions of Darlingine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5604 mL 22.8019 mL 45.6038 mL 91.2076 mL 114.0095 mL
5 mM 0.9121 mL 4.5604 mL 9.1208 mL 18.2415 mL 22.8019 mL
10 mM 0.456 mL 2.2802 mL 4.5604 mL 9.1208 mL 11.4009 mL
50 mM 0.0912 mL 0.456 mL 0.9121 mL 1.8242 mL 2.2802 mL
100 mM 0.0456 mL 0.228 mL 0.456 mL 0.9121 mL 1.1401 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Darlingine

10-Hydroxydarlingine, a new tropane alkaloid from the Australian proteaceous plant triunia erythrocarpa.[Pubmed:10843590]

J Nat Prod. 2000 May;63(5):688-9.

Triunia erythrocarpa was identified as containing alkaloids during chemical screening of Queensland Proteaceae using Dragendorff's reagent. A new tropane, 10-hydroxyDarlingine (1), and the known tropane, Darlingine (2), were isolated from the leaves of T. erythrocarpa. The absolute stereochemistry of 10-hydroxyDarlingine (1) was assigned using the advanced Mosher method. T. erythrocarpa is only the seventh member of the Proteaceae to have been shown to produce alkaloids.

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