Saikosaponin B3CAS# 58316-42-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 58316-42-0 | SDF | Download SDF |
| PubChem ID | 21637635 | Appearance | Powder |
| Formula | C43H72O14 | M.Wt | 813.02 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,4R,4aR,6aR,6bS,8S,8aS,12aS,14R,14aR,14bS)-8-hydroxy-4,8a-bis(hydroxymethyl)-14-methoxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol | ||
| SMILES | CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C(C=C5C4(CC(C6(C5CC(CC6)(C)C)CO)O)C)OC)C)C)O)OC7C(C(C(C(O7)CO)O)O)O)O | ||
| Standard InChIKey | GLQYFMRUYWFXGT-ZGFARVGISA-N | ||
| Standard InChI | InChI=1S/C43H72O14/c1-21-29(48)34(57-36-32(51)31(50)30(49)25(18-44)55-36)33(52)37(54-21)56-28-10-11-39(4)26(40(28,5)19-45)9-12-41(6)35(39)24(53-8)15-22-23-16-38(2,3)13-14-43(23,20-46)27(47)17-42(22,41)7/h15,21,23-37,44-52H,9-14,16-20H2,1-8H3/t21-,23+,24-,25-,26-,27+,28+,29+,30-,31+,32-,33-,34+,35-,36+,37+,39+,40+,41-,42-,43-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herb of Bupleurum chinense DC.
| Description | 1. Saikosaponin B3 shows some analgesic effect. |
| Targets | AChR |
Saikosaponin B3 Dilution Calculator
Saikosaponin B3 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.23 mL | 6.1499 mL | 12.2998 mL | 24.5996 mL | 30.7496 mL |
| 5 mM | 0.246 mL | 1.23 mL | 2.46 mL | 4.9199 mL | 6.1499 mL |
| 10 mM | 0.123 mL | 0.615 mL | 1.23 mL | 2.46 mL | 3.075 mL |
| 50 mM | 0.0246 mL | 0.123 mL | 0.246 mL | 0.492 mL | 0.615 mL |
| 100 mM | 0.0123 mL | 0.0615 mL | 0.123 mL | 0.246 mL | 0.3075 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Saikosaponin B2
Catalog No.:BCN5916
CAS No.:58316-41-9
- Kusunokinin
Catalog No.:BCN3226
CAS No.:58311-20-9
- Nanaomycin C
Catalog No.:BCC4016
CAS No.:58286-55-8
- Kakkalide
Catalog No.:BCN8263
CAS No.:58274-56-9
- ICA 069673
Catalog No.:BCC7911
CAS No.:582323-16-8
- BMS265246
Catalog No.:BCC3741
CAS No.:582315-72-8
- Betulin palmitate
Catalog No.:BCN5792
CAS No.:582315-55-7
- Tetraethyl ranelate
Catalog No.:BCC9177
CAS No.:58194-26-6
- H-DL-Ser-OMe.HCl
Catalog No.:BCC3100
CAS No.:5819-04-5
- Idebenone
Catalog No.:BCC4913
CAS No.:58186-27-9
- Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate
Catalog No.:BCC8975
CAS No.:58168-20-0
- Militarine
Catalog No.:BCN2551
CAS No.:58139-23-4
New Products
- 4,4'-Bis(N-carbazolyl)-1,1'-biphenyl
Catalog No.:BCC8660
CAS No.:58328-31-7
- Isopimaric acid
Catalog No.:BCN4618
CAS No.:5835-26-7
- DL-Demethylcoclaurine
Catalog No.:BCC8317
CAS No.:5843-65-2
- Dihydroresveratrol
Catalog No.:BCN5793
CAS No.:58436-28-5
- H-2-Nal-OH.HCl
Catalog No.:BCC3287
CAS No.:58438-03-2
- Boc-2-Nal-OH
Catalog No.:BCC3289
CAS No.:58438-04-3
- Angiotensin 1/2 (1-5)
Catalog No.:BCC1035
CAS No.:58442-64-1
- H-D-Leu-OMe.HCl
Catalog No.:BCC2681
CAS No.:5845-53-4
- N-(2-Hydroxy-4-methoxyphenyl)acetamide
Catalog No.:BCN1409
CAS No.:58469-06-0
- Darlingine
Catalog No.:BCN1906
CAS No.:58471-10-6
- Ferrugine
Catalog No.:BCN1910
CAS No.:58471-11-7
- Platycodin D
Catalog No.:BCN4982
CAS No.:58479-68-8
Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion.[Pubmed:25486247]
Molecules. 2014 Dec 4;19(12):20340-9.
Three saikosaponins were isolated from the MeOH extract of the roots of Bupleurum falcatum L.: saikosaponins B3 (1); B4 (2); and D (3). Of the three, compound 3 inhibited the interaction of selectins (E, L, and P) and THP-1 cells with IC50 values of 1.8, 3.0 and 4.3 microM, respectively. Also, the aglycone structure 4 of compound 3 showed moderate inhibitory activity on L-selectin-mediated cell adhesion. From these results, we suspect that compound 3 isolated from Bupleurum falcatum roots would be a good candidate for therapeutic strategies to treat inflammation.
Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells.
Saikosaponin B3,58316-42-0,Natural Products, buy Saikosaponin B3 , Saikosaponin B3 supplier , purchase Saikosaponin B3 , Saikosaponin B3 cost , Saikosaponin B3 manufacturer , order Saikosaponin B3 , high purity Saikosaponin B3
