Debilon

CAS# 26808-51-5

Debilon

Catalog No. BCN7696----Order now to get a substantial discount!

Product Name & Size Price Stock
Debilon: 5mg $828 In Stock
Debilon: 10mg Please Inquire In Stock
Debilon: 20mg Please Inquire Please Inquire
Debilon: 50mg Please Inquire Please Inquire
Debilon: 100mg Please Inquire Please Inquire
Debilon: 200mg Please Inquire Please Inquire
Debilon: 500mg Please Inquire Please Inquire
Debilon: 1000mg Please Inquire Please Inquire

Quality Control of Debilon

Number of papers citing our products

Chemical structure

Debilon

3D structure

Chemical Properties of Debilon

Cas No. 26808-51-5 SDF Download SDF
PubChem ID 57391584 Appearance Powder
Formula C15H22O2 M.Wt 234.33
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1aR,3R,7R,7aR,7bS)-3-hydroxy-1,1,7,7a-tetramethyl-1a,2,3,6,7,7b-hexahydrocyclopropa[a]naphthalen-5-one
SMILES CC1CC(=O)C=C2C1(C3C(C3(C)C)CC2O)C
Standard InChIKey ALMYSFNKELLWOO-XANOUDBCSA-N
Standard InChI InChI=1S/C15H22O2/c1-8-5-9(16)6-10-12(17)7-11-13(14(11,2)3)15(8,10)4/h6,8,11-13,17H,5,7H2,1-4H3/t8-,11-,12-,13+,15+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Debilon

The roots of Nardostachys chinensis.

Biological Activity of Debilon

Description1. Debilon shows cytotoxic activity against P-388 cells.
TargetsNO

Debilon Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Debilon Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Debilon

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2675 mL 21.3374 mL 42.6749 mL 85.3497 mL 106.6872 mL
5 mM 0.8535 mL 4.2675 mL 8.535 mL 17.0699 mL 21.3374 mL
10 mM 0.4267 mL 2.1337 mL 4.2675 mL 8.535 mL 10.6687 mL
50 mM 0.0853 mL 0.4267 mL 0.8535 mL 1.707 mL 2.1337 mL
100 mM 0.0427 mL 0.2134 mL 0.4267 mL 0.8535 mL 1.0669 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Debilon

Inhibitory constituents of Nardostachys chinensis on nitric oxide production in RAW 264.7 macrophages.[Pubmed:22079762]

Bioorg Med Chem Lett. 2012 Jan 1;22(1):706-8.

The activity-guided fractionation of the MeOH extract of the rhizomes and roots of Nardostachys chinensis led to the isolation of two new sesquiterpenoids, narchinol B (8) and narchinol C (9), along with 10 known compounds, ursolic acid (1), nardosinone (2), pinoresinol (3), desoxo-narchinol A (4), kanshone B (5), epoxyconiferyl alcohol (6), Debilon (7), 4alpha,5-dimethyl-1,3-dioxo-1,2,3,4,4alpha,5,6,7-octahydronaphthalene (10), p-coumaric acid (11), and isoferulic acid (12). Their structures were determined using spectroscopic techniques, which included 1D- and 2D-NMR. Among the isolates, compounds 2, 4, 5, 8 and 9 showed inhibitory activity against LPS-induced NO production with IC(50) values of 4.6-21.6 muM.

Cytotoxic sesquiterpenes from Nardostachys chinensis.[Pubmed:8370115]

Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1183-4.

Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), Debilon (3), nardosinonediol (4) and kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method. All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.

Keywords:

Debilon,26808-51-5,Natural Products, buy Debilon , Debilon supplier , purchase Debilon , Debilon cost , Debilon manufacturer , order Debilon , high purity Debilon

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: