DerroneCAS# 76166-59-1 |
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| Cas No. | 76166-59-1 | SDF | Download SDF |
| PubChem ID | 14704457 | Appearance | Yellow powder |
| Formula | C20H16O5 | M.Wt | 336.34 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethylpyrano[2,3-h]chromen-4-one | ||
| SMILES | CC1(C=CC2=C3C(=C(C=C2O1)O)C(=O)C(=CO3)C4=CC=C(C=C4)O)C | ||
| Standard InChIKey | ZSYPWSSGRVZENH-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C20H16O5/c1-20(2)8-7-13-16(25-20)9-15(22)17-18(23)14(10-24-19(13)17)11-3-5-12(21)6-4-11/h3-10,21-22H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Cudrania tricuspidata
| Description | 1. Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. 2. Derrone is a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids. |
| Targets | Antifection |
Derrone Dilution Calculator
Derrone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.9732 mL | 14.8659 mL | 29.7318 mL | 59.4636 mL | 74.3295 mL |
| 5 mM | 0.5946 mL | 2.9732 mL | 5.9464 mL | 11.8927 mL | 14.8659 mL |
| 10 mM | 0.2973 mL | 1.4866 mL | 2.9732 mL | 5.9464 mL | 7.433 mL |
| 50 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.1893 mL | 1.4866 mL |
| 100 mM | 0.0297 mL | 0.1487 mL | 0.2973 mL | 0.5946 mL | 0.7433 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antibacterial, antifungal and cytotoxic activities of two flavonoids from Retama raetam flowers.[Pubmed:22695233]
Molecules. 2012 Jun 13;17(6):7284-93.
We have investigated the antibacterial, antifungal and cytotoxic activities of two flavonoids isolated from Retama raetam flowers using the disc diffusion and micro-dilution broth methods. The cytotoxic activity was tested against Hep-2 cells using the MTT assay. The compounds licoflavone C (1) and Derrone (2) were active against Pseudomonas aeruginosa and Escherichia coli (7.81-15.62 mug/mL) and showed important antifungal activity. Strong antifungal activity against Candida species (7.81 mug/mL) was for example found with compound 2. The tested compounds also showed strong cytotoxicity against Hep-2 cells. These two compounds may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens.
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