Piptocarphin FCAS# 76215-53-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 76215-53-7 | SDF | Download SDF |
| PubChem ID | 6436819 | Appearance | Powder |
| Formula | C21H28O8 | M.Wt | 408.44 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CCOCC1=C2C(CC(C3(CCC(O3)(C=C2OC1=O)C)O)(C)O)OC(=O)C(=C)C | ||
| Standard InChIKey | UBMOPFJLLXVNIM-NTEUORMPSA-N | ||
| Standard InChI | InChI=1S/C21H28O8/c1-6-26-11-13-16-14(28-18(13)23)9-19(4)7-8-21(25,29-19)20(5,24)10-15(16)27-17(22)12(2)3/h9,15,24-25H,2,6-8,10-11H2,1,3-5H3/b14-9+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The aerial parts of Vernonia bockiana.
| Description | 1. Piptocarphin F shows strong cytotoxic activities against mouse lymphoid tumor cell line P388. 2. Piptocarphin F shows cytotoxic activity (IC50 3.87–12.5 umol·L−1) against the human leukemic cell line HL-60. |
Piptocarphin F Dilution Calculator
Piptocarphin F Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4483 mL | 12.2417 mL | 24.4834 mL | 48.9668 mL | 61.2085 mL |
| 5 mM | 0.4897 mL | 2.4483 mL | 4.8967 mL | 9.7934 mL | 12.2417 mL |
| 10 mM | 0.2448 mL | 1.2242 mL | 2.4483 mL | 4.8967 mL | 6.1209 mL |
| 50 mM | 0.049 mL | 0.2448 mL | 0.4897 mL | 0.9793 mL | 1.2242 mL |
| 100 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.4897 mL | 0.6121 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cytotoxic sesquiterpenoids from Vernonia bockiana.[Pubmed:18470811]
J Asian Nat Prod Res. 2008 May-Jun;10(5-6):571-5.
Two new sesquiterpenoids, vernobockolides A (1) and B (2), along with five known ones, piptocarphin C (3), Piptocarphin F (4), piptocarphin A (5), hirsutolide (6), and beta-d-glucopyranosyl taraxinic ester (7), were isolated from the aerial part of Vernonia bockiana. Their structures were determined by spectroscopic analysis, especially 2D NMR. Among them, compounds 2-6 showed strong cytotoxic activities against mouse lymphoid tumor cell line P388 with the IC(50) values of 1.81, 1.32, 0.77, and 0.73 microM, respectively.
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