Yukovanol

CAS# 76265-12-8

Yukovanol

Catalog No. BCN3699----Order now to get a substantial discount!

Product Name & Size Price Stock
Yukovanol: 5mg $725 In Stock
Yukovanol: 10mg Please Inquire In Stock
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Quality Control of Yukovanol

Number of papers citing our products

Chemical structure

Yukovanol

3D structure

Chemical Properties of Yukovanol

Cas No. 76265-12-8 SDF Download SDF
PubChem ID 14542257 Appearance Powder
Formula C20H18O6 M.Wt 354.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3,5-dihydroxy-2-(4-hydroxyphenyl)-8,8-dimethyl-2,3-dihydropyrano[2,3-h]chromen-4-one
SMILES CC1(C=CC2=C3C(=C(C=C2O1)O)C(=O)C(C(O3)C4=CC=C(C=C4)O)O)C
Standard InChIKey CXIZZLWYTVCYIE-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H18O6/c1-20(2)8-7-12-14(26-20)9-13(22)15-16(23)17(24)18(25-19(12)15)10-3-5-11(21)6-4-10/h3-9,17-18,21-22,24H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Yukovanol

The herbs of Phyllodium pulchellum

Biological Activity of Yukovanol

Description1. Yukovanol inhibits the proliferation of activated HSC-T6 cells in vitro.

Yukovanol Dilution Calculator

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Yukovanol Molarity Calculator

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Preparing Stock Solutions of Yukovanol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8209 mL 14.1044 mL 28.2087 mL 56.4175 mL 70.5219 mL
5 mM 0.5642 mL 2.8209 mL 5.6417 mL 11.2835 mL 14.1044 mL
10 mM 0.2821 mL 1.4104 mL 2.8209 mL 5.6417 mL 7.0522 mL
50 mM 0.0564 mL 0.2821 mL 0.5642 mL 1.1283 mL 1.4104 mL
100 mM 0.0282 mL 0.141 mL 0.2821 mL 0.5642 mL 0.7052 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Yukovanol

[Chemical constituents of Desmodium caudatum].[Pubmed:25090679]

Zhong Yao Cai. 2013 Dec;36(12):1953-6.

OBJECTIVE: To study the chemical constituents of Desmodium caudatum. METHODS: Silica column chromatography, Sephadex LH-20 column chromatography and recrystallization were used to separate and purify the chemical composition of Desmodium caudatum. Their chemical structures were identified by infrared spectrum (IR), mass spectrum (MS), nuclear magnetic resonance (NMR) and other physicochemical methods. RESULTS: Twelve compounds were isolated and identified as lacceroic acid(1), gheddic acid(2), stigmasterol(3), betulin(4), citrusinol(5), Yukovanol(6), kaempferol(7), protocatechuic acid(8), sophocarpine(9), matrine(10), N, Ndimethyltryptamine(11) and 5-hydroxy-N,N-dimethyltryptamine(12). CONCLUSION: Compounds 1, 2, 4 and 8-12 are isolated from this plant for the first time.

[Studies on constituents of rootsanel leaves from Desmodium blandum and their cytotoxic activity against growth of several tumor cells].[Pubmed:19160788]

Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2077-80.

OBJECTIVE: To investigate the chemical constituents of Desmodium blandum and their cytotoxic activity against the growth of several tumor cells. METHOD: Various chromatographic techniques including silica gel, Sephadex LH-20 column chromatography were employed for the isolation and purification of the constituents. The structures of compounds were elucidated by spectral analyses (IR, UV, NMR, MS). Their cytotoxic activity was then studied. RESULT: Eight compounds were isolated from the stems of D. blandum and identified as N, N-dimethyltryptamine (1), 5-methoxy-N, N-dimethyltryptamine (2), citrusinol (3), Yukovanol (4), (Z)-1-(4-hydroxy-2, 3-dimethoxyphenyl)-3-(4-hydroxyphenyl) propene (5), (Z)-1-(3-hydroxy-2, 4-dimethoxy-phenyl)-3-(4-hydroxy-3-methoxy-phenyl) propene (6), methylprotocatechuate (7), katuranin (8). CONCLUSION: Among these compounds, compound 6 was isolated from D. blandum for the first time. In the MTT test, compounds 2 and 6 exhibit cytotoxic activities against the KB cell, and compounds 3 and 6 exhibit the same activities against the HepG2 cell.

[Chemical constituents against hepatic fibrosis from Phyllodium pulchellum roots].[Pubmed:25174106]

Zhong Yao Cai. 2014 Mar;37(3):424-7.

OBJECTIVE: To investigate the bioactive constituents against hepatic fibrosis from the roots of Phyllodium pulchellum. METHODS: The chemical constituents of Phyllodium pulchellum roots were obtained by various chromatographic technologies and identified by several spectroscopic methods. RESULTS: Ten compounds were elucidated as 3,5,2',4'-tetrahydroxy-2",2"-dimethylpyrano-[5",6",7,8] -flavanone (1), Yukovanol (2), citflavanone (3), 8-prenylated 5,7,3',4'-tetrahydroxyflavanone (4), pulchelstyrene A (5), pulchelstyrene B (6), pulchelstyrene D (7), 3-indolcarbaldehyde (8), 3-methoxyindole (9) and p-hydroxybenzoic acid (10). The effects to inhibit the proliferation of activated HSC-T6 cells of all isolated compounds were also evaluated. CONCLUSION: All compounds are isolated from this plant for the first time except for compounds 5 - 7. Compounds 2,4,5 and 6 can inhibit the proliferation of activated HSC-T6 cells in vitro.

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