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Drynachromoside A

CAS# 1507388-29-5

Drynachromoside A

2D Structure

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Quality Control of Drynachromoside A

3D structure

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Drynachromoside A

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Chemical Properties of Drynachromoside A

Cas No. 1507388-29-5 SDF Download SDF
PubChem ID 71661133 Appearance Powder
Formula C22H28O13 M.Wt 500.45
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-[(2S,3R,4S,5R,6S)-3,4-dihydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-methylchromen-4-one
SMILES CC1C(C(C(C(O1)OC2=CC(=C3C(=C2)OC(=CC3=O)C)O)O)O)OC4C(C(C(C(O4)CO)O)O)O
Standard InChIKey BEVXGYXIMDDDHJ-HHLLRHCNSA-N
Standard InChI InChI=1S/C22H28O13/c1-7-3-10(24)14-11(25)4-9(5-12(14)31-7)33-21-19(30)17(28)20(8(2)32-21)35-22-18(29)16(27)15(26)13(6-23)34-22/h3-5,8,13,15-23,25-30H,6H2,1-2H3/t8-,13+,15+,16-,17-,18+,19+,20-,21-,22-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Drynachromoside A

The herbs of Drynaria fortunei

Biological Activity of Drynachromoside A

Description1. Drynachromoside A exhibits the biochemical effects on the proliferation of MC3T3-E1 cells.

Drynachromoside A Dilution Calculator

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Drynachromoside A Molarity Calculator

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Preparing Stock Solutions of Drynachromoside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9982 mL 9.991 mL 19.982 mL 39.964 mL 49.955 mL
5 mM 0.3996 mL 1.9982 mL 3.9964 mL 7.9928 mL 9.991 mL
10 mM 0.1998 mL 0.9991 mL 1.9982 mL 3.9964 mL 4.9955 mL
50 mM 0.04 mL 0.1998 mL 0.3996 mL 0.7993 mL 0.9991 mL
100 mM 0.02 mL 0.0999 mL 0.1998 mL 0.3996 mL 0.4996 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Drynachromoside A

Two new chromone glycosides from Drynaria fortunei.[Pubmed:23160089]

Fitoterapia. 2013 Jan;84:130-4.

Two new chromone glycosides, Drynachromoside A (1), drynachromoside B (2), along with three known flavanones, 5,7,3',5'-tetrahydroxy-flavanone (3), 5,7,3',5'-tetrahydroxy-flavanone-7-O-beta-d-glucopyranoside (4), and 5,7,3',5'-tetrahydroxy-flavanone-7-O-neohesperidoside (5), were isolated from the dry rhizomes of Drynaria fortunei by means of bio-active screening. The two former compounds were elucidated on the basis of physico-chemical property and spectroscopic data. The osteoblastic proliferation activities of these flavonoids were evaluated by the method of MTT. The results showed that compound 1 exhibited the biochemical effects on the proliferation of MC3T3-E1 cells, while Compound 2 showed inhibitory effects against MC3T3-E1 cells.

Five new chromone glycosides from Scindapsus officinalis (Roxb.) Schott.[Pubmed:28882671]

Fitoterapia. 2017 Oct;122:101-106.

Five new chromone glycosides, officinalisides A (1), B (2), C (3), D (4) and E (5) were isolated from Scindapsus officinalis (Roxb.) Schott., along with six known chromone derivatives, 7-O-alpha-l-rhamnosyl-nereugenin (6), undulatoside A (7), Drynachromoside A (8), drynachromoside B (9), 5,7-dihydroxy-2-methyl chromone(10), 5,7-dihydroxy-2-hydroxymethyl chromone (11). Structural elucidation of the isolated compounds was established by spectroscopic analysis, especially 2D NMR techniques and comparison with literatures. The isolates were evaluated for anti-inflammatory activities in a LPS-stimulated RAW 264.7 model using inhibition of nitric oxide (NO) production as an indicator. Compounds 2, 4 and 10 demonstrated potential anti-inflammatory activity with IC50 values of 16.1, 19.1, and 13.4muM, respectively, compared to the positive control dexamethasone.

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