EchinulinCAS# 1859-87-6 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 1859-87-6 | SDF | Download SDF |
| PubChem ID | 115252 | Appearance | Powder |
| Formula | C29H39N3O2 | M.Wt | 461.7 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (3S,6S)-3-methyl-6-[[2-(2-methylbut-3-en-2-yl)-5,7-bis(3-methylbut-2-enyl)-1H-indol-3-yl]methyl]piperazine-2,5-dione | ||
| SMILES | CC1C(=O)NC(C(=O)N1)CC2=C(NC3=C(C=C(C=C23)CC=C(C)C)CC=C(C)C)C(C)(C)C=C | ||
| Standard InChIKey | DIKMWTRJIZQJMY-CYFREDJKSA-N | ||
| Standard InChI | InChI=1S/C29H39N3O2/c1-9-29(7,8)26-23(16-24-28(34)30-19(6)27(33)31-24)22-15-20(12-10-17(2)3)14-21(25(22)32-26)13-11-18(4)5/h9-11,14-15,19,24,32H,1,12-13,16H2,2-8H3,(H,30,34)(H,31,33)/t19-,24-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Echinulin has toxicity in rabbits. |
Echinulin Dilution Calculator
Echinulin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1659 mL | 10.8295 mL | 21.6591 mL | 43.3182 mL | 54.1477 mL |
| 5 mM | 0.4332 mL | 2.1659 mL | 4.3318 mL | 8.6636 mL | 10.8295 mL |
| 10 mM | 0.2166 mL | 1.083 mL | 2.1659 mL | 4.3318 mL | 5.4148 mL |
| 50 mM | 0.0433 mL | 0.2166 mL | 0.4332 mL | 0.8664 mL | 1.083 mL |
| 100 mM | 0.0217 mL | 0.1083 mL | 0.2166 mL | 0.4332 mL | 0.5415 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Toxicity of echinulin from Aspergillus chevalieri in rabbits.[Pubmed:2781591]
Toxicol Lett. 1989 Sep;48(3):235-41.
Rabbits were injected intraperitoneally with purified Echinulin, a product of Aspergillus chevalieri. After 2 h, the rabbits were bled and enzyme analyses were carried out on the supernates of liver homogenates and citrated plasma. Elevated levels of total plasma lactate dehydrogenase, cardiac derived isozyme, glutamic-oxaloacetic and glutamic-pyruvic transaminase activities in animals receiving toxin were observed. These levels were statistically significant compared to the vehicle control. A significant increase in liver lactate dehydrogenase of toxin-treated rabbits was also observed. Light-microscopic examination of lung and liver showed a significant degree of damage. The increase in plasma enzyme levels is indicative of damage to these organs.
Eurotium spp. and echinulin in feed refused by swine.[Pubmed:3377495]
Appl Environ Microbiol. 1988 Mar;54(3):830-1.
Feed refused by swine contained a high-propagule density of Eurotium chevalieri Mangin (anamorph, Aspergillus chevalieri (Mangin) Thom and Church), Eurotium amstelodami Mangin (anamorph, Aspergillus amstelodami (Mangin Thom and Church), and Aspergillus candidus Link. Echinulin (8 micrograms/g of feed) was detected in the feed. Isolates of E. chevalieri and E. amstelodami but not A. candidus produced Echinulin on rice or cracked corn. Mice refused to drink water containing 90 micrograms of Echinulin per ml. This is the first report of the alkaloid Echinulin in feed refused by swine.
