ErmaninCAS# 20869-95-8 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 20869-95-8 | SDF | Download SDF |
| PubChem ID | 5352001 | Appearance | Yellow powder |
| Formula | C17H14O6 | M.Wt | 314.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)chromen-4-one | ||
| SMILES | COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC | ||
| Standard InChIKey | RJCJVIFSIXKSAH-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H14O6/c1-21-11-5-3-9(4-6-11)16-17(22-2)15(20)14-12(19)7-10(18)8-13(14)23-16/h3-8,18-19H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Ermanin shows anti-inflammatory activity by suppressing the iNOS and COX-2 expression. 2. Ermanin has a high deterrent activity at 40 ppm against Dione juno larvae. 3. Ermanin may have anti-HIV-1activity. |
| Targets | NO | PGE | NOS | COX | HIV | Antifection |
Ermanin Dilution Calculator
Ermanin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1817 mL | 15.9084 mL | 31.8167 mL | 63.6335 mL | 79.5418 mL |
| 5 mM | 0.6363 mL | 3.1817 mL | 6.3633 mL | 12.7267 mL | 15.9084 mL |
| 10 mM | 0.3182 mL | 1.5908 mL | 3.1817 mL | 6.3633 mL | 7.9542 mL |
| 50 mM | 0.0636 mL | 0.3182 mL | 0.6363 mL | 1.2727 mL | 1.5908 mL |
| 100 mM | 0.0318 mL | 0.1591 mL | 0.3182 mL | 0.6363 mL | 0.7954 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Boc-His(Boc)-OH
Catalog No.:BCC3399
CAS No.:20866-46-0
- Berberine
Catalog No.:BCN4911
CAS No.:2086-83-1
- Primulic Acid 2
Catalog No.:BCC8237
CAS No.:208599-88-6
- H-Tle-OH
Catalog No.:BCC2659
CAS No.:20859-02-3
- Micafungin sodium
Catalog No.:BCC1750
CAS No.:208538-73-2
- Protoaescigenin
Catalog No.:BCC8240
CAS No.:20853-07-0
- Stigmastane-3,5,6-triol
Catalog No.:BCN4910
CAS No.:20835-91-0
- Ethyl 4-(rhamnosyloxy)benzylcarbamate
Catalog No.:BCN7635
CAS No.:208346-80-9
- Gentiopicroside
Catalog No.:BCN4909
CAS No.:20831-76-9
- Daunorubicin
Catalog No.:BCC4115
CAS No.:20830-81-3
- Digoxin
Catalog No.:BCN5359
CAS No.:20830-75-5
- ZM336372
Catalog No.:BCC3875
CAS No.:208260-29-1
- (1R,1'S,3'R/1R,1'R,3'S)-L-054,264
Catalog No.:BCC7364
CAS No.:208706-12-1
- Saikosaponin D
Catalog No.:BCN1088
CAS No.:20874-52-6
- Testosterone benzoate
Catalog No.:BCC9166
CAS No.:2088-71-3
- Swertianin
Catalog No.:BCC8258
CAS No.:20882-75-1
- JWH 073
Catalog No.:BCC1674
CAS No.:208987-48-8
- Mangochinine
Catalog No.:BCN4913
CAS No.:209115-67-3
- Obtucarbamate B
Catalog No.:BCN3937
CAS No.:20913-18-2
- Entecavir Hydrate
Catalog No.:BCC1109
CAS No.:209216-23-9
- Fmoc- ß-HoAsp(OtBu)-OH
Catalog No.:BCC3230
CAS No.:209252-17-5
- Neocryptomerin
Catalog No.:BCN8023
CAS No.:20931-36-6
- Beta-mangostin
Catalog No.:BCN1213
CAS No.:20931-37-7
- Platycoside A
Catalog No.:BCN3241
CAS No.:209404-00-2
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum.[Pubmed:16979127]
Int Immunopharmacol. 2006 Nov;6(11):1723-8.
Plant flavonoids show anti-inflammatory activity both in vitro and in vivo. Some flavonoids have been reported previously to inhibit nitric oxide (NO) and prostaglandin E2 (PGE2) production by suppressing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression. The present study focuses on the effect of various naturally occurring flavonoids (santin, Ermanin, centaureidin and 5,3'-dihydroxy-4'-methoxy-7-methoxycarbonylflavonol) on modulation of lipopolysaccharide (LPS)-induced iNOS and COX-2 expression in RAW 264.7 cells. Western blotting showed that all flavonoids suppressed the induction of both iNOS and COX-2. Ermanin and 5,3'-dihydroxy-4'-methoxy-7-methoxycarbonylflavonol were the most potent inhibitors. This study suggests that inhibition of iNOS and COX-2 expression by flavonoids may be one of the mechanisms responsible for their anti-inflammatory effects, and that they may be potential agents for use in the treatment of inflammatory diseases.
Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla.[Pubmed:20013639]
Planta Med. 2010 May;76(7):721-5.
Bioassay-guided fractionation and purification of the anti-HIV-1-active MeOH extract from the leaves and twigs of Polyalthia sclerophylla led to the isolation of two new compounds, ENT-kaur-sclerodimer ( 1) and cyclotucanol 3-palmitate ( 2), along with the known ENT-kaur-16-en-19-oic acid ( 3), 15 beta-hydroxy- ENT-kaur-16-en-19-oic acid ( 4), 15 beta-acetoxy- ENT-kaur-16-en-19-oic acid ( 5), 15-oxo- ENT-kaur-16-en-19-oic acid ( 6), 16 alpha,17-dihydroxy- ENT-kauran-19-oic acid ( 7), 16 alpha-hydroxy- ENT-kauran-19-oic acid (xylopic acid) ( 8), a pseudodimer (15 alpha-hydroxy- ENT-kaur-16-en-19-oic acid/17-hydroxy- ENT-kaur-15-en-19-oic acid) ( 9), Ermanin, nicotiflorin, and allantoin. Among these isolates, compound 3 was the most active in both anti-syncytium (EC (50) 13.7 microg/mL and selectivity index 3.1) and HIV-1 reverse transcriptase (IC (50) 34.1 microg/mL) assays.
