Neocryptomerin

CAS# 20931-36-6

Neocryptomerin

Catalog No. BCN8023----Order now to get a substantial discount!

Product Name & Size Price Stock
Neocryptomerin: 5mg Please Inquire In Stock
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Quality Control of Neocryptomerin

Number of papers citing our products

Chemical structure

Neocryptomerin

3D structure

Chemical Properties of Neocryptomerin

Cas No. 20931-36-6 SDF Download SDF
PubChem ID 5320065 Appearance Powder
Formula C31H20O10 M.Wt 552.48
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7-dihydroxy-6-[4-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)phenoxy]-2-(4-hydroxyphenyl)chromen-4-one
SMILES COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)OC4=C(C=C5C(=C4O)C(=O)C=C(O5)C6=CC=C(C=C6)O)O)O
Standard InChIKey YEMFTKDEHYFESW-UHFFFAOYSA-N
Standard InChI InChI=1S/C31H20O10/c1-38-19-10-20(33)28-21(34)12-24(40-26(28)11-19)16-4-8-18(9-5-16)39-31-23(36)14-27-29(30(31)37)22(35)13-25(41-27)15-2-6-17(32)7-3-15/h2-14,32-33,36-37H,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Neocryptomerin

The herbs of Podocarpus macrophyllus

Biological Activity of Neocryptomerin

In vitro

Isolation and cytotoxic activity of selaginellin derivatives and biflavonoids from Selaginella tamariscina.[Pubmed: 22271084 ]

Planta Med. 2012 Mar;78(4):390-2.


METHODS AND RESULTS:
Five selaginellin derivatives, including two new selaginellins termed selaginellins M (1) and N (2), and three previously identified compounds, selaginellin (3), selaginellin A (4), and selaginellin C (5), were isolated from the Selaginella tamariscina (Beauv.) Spring plant. In addition, four known biflavonoids, namely Neocryptomerin ( 6), hinokiflavone (7), pulvinatabiflavone (8), and 7''- O-methylamentoflavone (9), were also isolated. The structures of new compounds 1 and 2 were elucidated by spectroscopic analysis. The cytotoxic activity of compounds 1- 9 was evaluated against a small panel of human cancer cell lines, including U251 (human glioma cells), HeLa (human cervical carcinoma cells), and MCF-7 (human breast cancer cells).
CONCLUSIONS:
The two new selaginellins, selaginellins M (1) and N (2), showed medium activity against the human cancer cell lines.

Neocryptomerin Dilution Calculator

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Neocryptomerin Molarity Calculator

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Preparing Stock Solutions of Neocryptomerin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.81 mL 9.0501 mL 18.1002 mL 36.2004 mL 45.2505 mL
5 mM 0.362 mL 1.81 mL 3.62 mL 7.2401 mL 9.0501 mL
10 mM 0.181 mL 0.905 mL 1.81 mL 3.62 mL 4.5251 mL
50 mM 0.0362 mL 0.181 mL 0.362 mL 0.724 mL 0.905 mL
100 mM 0.0181 mL 0.0905 mL 0.181 mL 0.362 mL 0.4525 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Neocryptomerin

Isolation and cytotoxic activity of selaginellin derivatives and biflavonoids from Selaginella tamariscina.[Pubmed:22271084]

Planta Med. 2012 Mar;78(4):390-2.

Five selaginellin derivatives, including two new selaginellins termed selaginellins M (1) and N (2), and three previously identified compounds, selaginellin (3), selaginellin A (4), and selaginellin C (5), were isolated from the Selaginella tamariscina (Beauv.) Spring plant. In addition, four known biflavonoids, namely Neocryptomerin ( 6), hinokiflavone (7), pulvinatabiflavone (8), and 7''- O-methylamentoflavone (9), were also isolated. The structures of new compounds 1 and 2 were elucidated by spectroscopic analysis. The cytotoxic activity of compounds 1- 9 was evaluated against a small panel of human cancer cell lines, including U251 (human glioma cells), HeLa (human cervical carcinoma cells), and MCF-7 (human breast cancer cells). The two new selaginellins, selaginellins M (1) and N (2), showed medium activity against the human cancer cell lines.

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