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Ethyl 4-hydroxyphenylacetate

CAS# 17138-28-2

Ethyl 4-hydroxyphenylacetate

Catalog No. BCN3792----Order now to get a substantial discount!

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Quality Control of Ethyl 4-hydroxyphenylacetate

Number of papers citing our products

Chemical structure

Ethyl 4-hydroxyphenylacetate

3D structure

Chemical Properties of Ethyl 4-hydroxyphenylacetate

Cas No. 17138-28-2 SDF Download SDF
PubChem ID 28310 Appearance Oil
Formula C10H12O3 M.Wt 180.2
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name ethyl 2-(4-hydroxyphenyl)acetate
SMILES CCOC(=O)CC1=CC=C(C=C1)O
Standard InChIKey HYUPPKVFCGIMDB-UHFFFAOYSA-N
Standard InChI InChI=1S/C10H12O3/c1-2-13-10(12)7-8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ethyl 4-hydroxyphenylacetate

The fruit of Moringa oleifera

Biological Activity of Ethyl 4-hydroxyphenylacetate

DescriptionEthyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A.
TargetsMAO

Protocol of Ethyl 4-hydroxyphenylacetate

Kinase Assay

Monoamine oxidase A-inhibiting components of urinary tribulin: purification and identification.[Pubmed: 8527006]

J Neural Transm Park Dis Dement Sect. 1995;9(2-3):225-37.

The endogenous monoamine oxidase (MAO) inhibitory activity, termed tribulin, contains several components. We have previously identified one of them, isatin, which is a selective inhibitor of MAO B.
METHODS AND RESULTS:
In the present study we have purified several further components of human urinary tribulin which act as selective inhibitors of MAO A. They have been identified by gas chromatography-mass spectrometry (GC-MS) as ethyl indole-3-acetate (and/or methyl indole-3-propionate), methyl indole-3-acetate and Ethyl 4-hydroxyphenylacetate. IC50 values for MAO A were found to be 44 microM (105 microM for methyl indole-3-propionate), 88 microM and 120 microM, respectively, whilst those for MAO B were each greater than 1 mM. The artificial formation of these esters was excluded by carrying the parent acids, from which they are presumably synthesized, through the purification procedure.
CONCLUSIONS:
As tribulin output is increased during stress or anxiety, these results point to a possible role for tryptamine and tyramine pathways in such disorders.

Ethyl 4-hydroxyphenylacetate Dilution Calculator

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Ethyl 4-hydroxyphenylacetate Molarity Calculator

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Preparing Stock Solutions of Ethyl 4-hydroxyphenylacetate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.5494 mL 27.7469 mL 55.4939 mL 110.9878 mL 138.7347 mL
5 mM 1.1099 mL 5.5494 mL 11.0988 mL 22.1976 mL 27.7469 mL
10 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
50 mM 0.111 mL 0.5549 mL 1.1099 mL 2.2198 mL 2.7747 mL
100 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ethyl 4-hydroxyphenylacetate

Monoamine oxidase A-inhibiting components of urinary tribulin: purification and identification.[Pubmed:8527006]

J Neural Transm Park Dis Dement Sect. 1995;9(2-3):225-37.

The endogenous monoamine oxidase (MAO) inhibitory activity, termed tribulin, contains several components. We have previously identified one of them, isatin, which is a selective inhibitor of MAO B. In the present study we have purified several further components of human urinary tribulin which act as selective inhibitors of MAO A. They have been identified by gas chromatography-mass spectrometry (GC-MS) as ethyl indole-3-acetate (and/or methyl indole-3-propionate), methyl indole-3-acetate and Ethyl 4-hydroxyphenylacetate. IC50 values for MAO A were found to be 44 microM (105 microM for methyl indole-3-propionate), 88 microM and 120 microM, respectively, whilst those for MAO B were each greater than 1 mM. The artificial formation of these esters was excluded by carrying the parent acids, from which they are presumably synthesized, through the purification procedure. As tribulin output is increased during stress or anxiety, these results point to a possible role for tryptamine and tyramine pathways in such disorders.

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