Aburatubolactam ACAS# 170894-24-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 170894-24-3 | SDF | Download SDF |
| PubChem ID | 132350823 | Appearance | Powder |
| Formula | C30H40N2O5 | M.Wt | 508.66 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1E,3E,5E,8R,9S,10S,11R,13R,15S,16Z,18E,24S,25S)-11-ethyl-2,24-dihydroxy-10,26-dimethyl-21,26-diazatetracyclo[23.2.1.08,15.09,13]octacosa-1,3,5,16,18-pentaene-20,27,28-trione | ||
| SMILES | CCC1CC2CC3C=CC=CC(=O)NCCC(C4C(=O)C(=C(C=CC=CCC3C2C1C)O)C(=O)N4C)O | ||
| Standard InChIKey | RYVUSTXQTVYINS-CKZXNOOWSA-N | ||
| Standard InChI | InChI=1S/C30H40N2O5/c1-4-19-16-21-17-20-10-8-9-13-25(35)31-15-14-24(34)28-29(36)27(30(37)32(28)3)23(33)12-7-5-6-11-22(20)26(21)18(19)2/h5-10,12-13,18-22,24,26,28,33-34H,4,11,14-17H2,1-3H3,(H,31,35)/b6-5+,10-8-,12-7+,13-9+,27-23+/t18-,19+,20+,21+,22+,24-,26+,28-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The Streptomyces sp.
| Description | 1. Aburatubolactam A is an inhibitor of superoxide anion generation. 2. Aburatubolactam A has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging. |
| Targets | Immunology & Inflammation related |
Aburatubolactam A Dilution Calculator
Aburatubolactam A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9659 mL | 9.8297 mL | 19.6595 mL | 39.319 mL | 49.1487 mL |
| 5 mM | 0.3932 mL | 1.9659 mL | 3.9319 mL | 7.8638 mL | 9.8297 mL |
| 10 mM | 0.1966 mL | 0.983 mL | 1.9659 mL | 3.9319 mL | 4.9149 mL |
| 50 mM | 0.0393 mL | 0.1966 mL | 0.3932 mL | 0.7864 mL | 0.983 mL |
| 100 mM | 0.0197 mL | 0.0983 mL | 0.1966 mL | 0.3932 mL | 0.4915 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Aburatubolactam A, a novel inhibitor of superoxide anion generation from a marine microorganism.
Heterocyclic Communications, 1996, 2(4):315-8.
Aburatubolactam A (1), isolated from the cultured broth of a Streptomyces sp., SCRC-A20, separated from a mollusk, potently inhibited superoxide anion generation. The structure of Aburatubolactam A was determined by X-ray crystallographic analysis and the complete assignment of the resonances in the 1H-NMR spectrum was achieved.
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