Flavaprin

CAS# 53846-49-4

Flavaprin

Catalog No. BCN5714----Order now to get a substantial discount!

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Chemical structure

Flavaprin

3D structure

Chemical Properties of Flavaprin

Cas No. 53846-49-4 SDF Download SDF
PubChem ID 21577888 Appearance Powder
Formula C26H30O10 M.Wt 502.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-5-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
SMILES CC(=CCC1=C(C=C(C2=C1OC(CC2=O)C3=CC=C(C=C3)O)O)OC4C(C(C(C(O4)CO)O)O)O)C
Standard InChIKey BMYUIXRQCPBGKG-WTYMVSKMSA-N
Standard InChI InChI=1S/C26H30O10/c1-12(2)3-8-15-19(35-26-24(33)23(32)22(31)20(11-27)36-26)10-17(30)21-16(29)9-18(34-25(15)21)13-4-6-14(28)7-5-13/h3-7,10,18,20,22-24,26-28,30-33H,8-9,11H2,1-2H3/t18-,20+,22+,23-,24+,26+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Flavaprin

The fruits of Evodia rutaecarpa (Juss.) Benth.

Biological Activity of Flavaprin

In vitro

Constituents of the fruits and leaves of Euodia daniellii.[Pubmed: 12510833]

Arch Pharm Res. 2002 Dec;25(6):824-30.


METHODS AND RESULTS:
Four flavonoid glycosides, Flavaprin (7), evodioside B (8), vitexin (11), and hesperidin (12), as well as the coumarins bergapten (1), xanthotoxin (2), and isopimpinellin (3), the lignan simplexoside (10), the steroids beta-sitosterol (4) and daucosterol (5), the limonoids isolimonexic acid (6) and limonin (9), and uracil (13) and myo-inositol (14) have been isolated from Euodia daniellii. The structures of these compounds were established from spectral data.
CONCLUSIONS:
Among the isolates, bergapten showed cyclooxygenase-2 inhibitory activity with an IC50 value of 6.2 microg/ml. Flavonoids isolated from this plant exhibited no cytotoxic activity against the human tumor cell lines, A549, SKOV-3, SKMEL-2, XF498, and HCT15.

Flavaprin Dilution Calculator

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Flavaprin Molarity Calculator

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Preparing Stock Solutions of Flavaprin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.99 mL 9.9502 mL 19.9005 mL 39.801 mL 49.7512 mL
5 mM 0.398 mL 1.99 mL 3.9801 mL 7.9602 mL 9.9502 mL
10 mM 0.199 mL 0.995 mL 1.99 mL 3.9801 mL 4.9751 mL
50 mM 0.0398 mL 0.199 mL 0.398 mL 0.796 mL 0.995 mL
100 mM 0.0199 mL 0.0995 mL 0.199 mL 0.398 mL 0.4975 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Flavaprin

Constituents of the fruits and leaves of Euodia daniellii.[Pubmed:12510833]

Arch Pharm Res. 2002 Dec;25(6):824-30.

Four flavonoid glycosides, Flavaprin (7), evodioside B (8), vitexin (11), and hesperidin (12), as well as the coumarins bergapten (1), xanthotoxin (2), and isopimpinellin (3), the lignan simplexoside (10), the steroids beta-sitosterol (4) and daucosterol (5), the limonoids isolimonexic acid (6) and limonin (9), and uracil (13) and myo-inositol (14) have been isolated from Euodia daniellii. The structures of these compounds were established from spectral data. Among the isolates, bergapten showed cyclooxygenase-2 inhibitory activity with an IC50 value of 6.2 microg/ml. Flavonoids isolated from this plant exhibited no cytotoxic activity against the human tumor cell lines, A549, SKOV-3, SKMEL-2, XF498, and HCT15.

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