Forrestin A

CAS# 152175-76-3

Forrestin A

Catalog No. BCN1677----Order now to get a substantial discount!

Product Name & Size Price Stock
Forrestin A: 5mg $989 In Stock
Forrestin A: 10mg Please Inquire In Stock
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Quality Control of Forrestin A

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Chemical structure

Forrestin A

3D structure

Chemical Properties of Forrestin A

Cas No. 152175-76-3 SDF Download SDF
PubChem ID 91884971 Appearance Powder
Formula C30H42O11 M.Wt 578.7
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1R,2R,3R,4S,6S,8S,9R,10R,11S,13S,15R)-2,3,8,15-tetraacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate
SMILES CC(=O)OC1CC2CC3(C1C4(C(CC(C(C4C(C3OC(=O)C)OC(=O)C)(C)C)O)OC(=O)C)C)C(C2=C)OC(=O)C
Standard InChIKey IBZKZJFIBDPMSV-XKIVFHDSSA-N
Standard InChI InChI=1S/C30H42O11/c1-13-19-10-20(37-14(2)31)24-29(9)22(38-15(3)32)11-21(36)28(7,8)25(29)23(39-16(4)33)27(41-18(6)35)30(24,12-19)26(13)40-17(5)34/h19-27,36H,1,10-12H2,2-9H3/t19-,20+,21+,22+,23-,24-,25+,26-,27+,29-,30-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Forrestin A

The herbs of Rabdosia amethystoides

Forrestin A Dilution Calculator

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Forrestin A Molarity Calculator

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Preparing Stock Solutions of Forrestin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.728 mL 8.6401 mL 17.2801 mL 34.5602 mL 43.2003 mL
5 mM 0.3456 mL 1.728 mL 3.456 mL 6.912 mL 8.6401 mL
10 mM 0.1728 mL 0.864 mL 1.728 mL 3.456 mL 4.32 mL
50 mM 0.0346 mL 0.1728 mL 0.3456 mL 0.6912 mL 0.864 mL
100 mM 0.0173 mL 0.0864 mL 0.1728 mL 0.3456 mL 0.432 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Forrestin A

New Labdane diterpenes from Hedychium yunnanense with cytotoxicity and inhibitory effects on nitric oxide production.[Pubmed:26965832]

Nat Prod Res. 2016 Dec;30(23):2669-2674.

Two new labdane diterpenes, hedychenoids A (1) and B (2), were isolated from the rhizomes of Hedychium yunnanense, together with four known ones hedychenone (3), Forrestin A (4), villosin (5) and calcaratarin C (6). Their structures were determined on the basis of NMR (1D and 2D) and mass spectroscopic analysis. Compounds 2, 3 and 5 exhibited cytotoxicity against SGC-7901 with IC50 values of 14.88 +/- 0.52, 7.08 +/- 0.21 and 7.76 +/- 0.21 mug/ml, 3 and 5 against HeLa with IC50 values of 9.76 +/- 0.48 and 13.24 +/- 0.63 mug/ml, respectively. Compounds 2, 5 showed inhibitory effects against nitric oxide production in LPS and IFN-gamma-induced RAW 264.7 murine macrophages with IC50 values of 6.57 +/- 0.88 and 5.99 +/- 1.20 mug/ml, respectively.

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