Ganoderiol DCAS# 114567-45-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 114567-45-2 | SDF | Download SDF |
| PubChem ID | 15602261 | Appearance | Powder |
| Formula | C30H48O5 | M.Wt | 488.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4,4,10,13,14-pentamethyl-17-(5,6,7-trihydroxy-6-methylheptan-2-yl)-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,7-dione | ||
| SMILES | CC(CCC(C(C)(CO)O)O)C1CCC2(C1(CCC3=C2C(=O)CC4C3(CCC(=O)C4(C)C)C)C)C | ||
| Standard InChIKey | NAETYGPWGSNZTO-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C30H48O5/c1-18(8-9-24(34)30(7,35)17-31)19-10-15-29(6)25-20(11-14-28(19,29)5)27(4)13-12-23(33)26(2,3)22(27)16-21(25)32/h18-19,22,24,31,34-35H,8-17H2,1-7H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Ganoderiol D Dilution Calculator
Ganoderiol D Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0462 mL | 10.2312 mL | 20.4625 mL | 40.9249 mL | 51.1561 mL |
| 5 mM | 0.4092 mL | 2.0462 mL | 4.0925 mL | 8.185 mL | 10.2312 mL |
| 10 mM | 0.2046 mL | 1.0231 mL | 2.0462 mL | 4.0925 mL | 5.1156 mL |
| 50 mM | 0.0409 mL | 0.2046 mL | 0.4092 mL | 0.8185 mL | 1.0231 mL |
| 100 mM | 0.0205 mL | 0.1023 mL | 0.2046 mL | 0.4092 mL | 0.5116 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Lanostane triterpenoids from the fruiting bodies of Ganoderma hainanense and their cytotoxic activity.[Pubmed:35771834]
J Asian Nat Prod Res. 2022 Jun 30:1-7.
Three undescribed lanostane triterpenoids, 24E-en-11-oxo-Ganoderiol D (1), 11beta-hydroxy-Ganoderiol D (2), and 11beta-hydroxy-lucidone H (3) were isolated from the 80% EtOH extract of the fruiting bodies of Ganoderma hainanense. Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D ((1)H-(1)H COSY, HMQC, and HMBC) NMR spectroscopy. All the triterpenoids were in vitro evaluated for their cytotoxic activities against six mammary adenocarcinoma cell lines (MCF7, MDA-MB-231, SK-BR-3, BT-20, HCC38, and AU565). As a result, compound 3 exhibited significant cytotoxic activities against all tested cell lines with IC(50) values less than 20 muM.
Antimicrobial lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum.[Pubmed:34923886]
J Asian Nat Prod Res. 2022 Nov;24(11):1001-1007.
A chemical investigation on the 90% EtOH extract of the fruiting bodies of Ganoderma applanatum led to the isolation of three new lanostane triterpenoids, designated as 25-methoxy-11-oxo-Ganoderiol D (1), 3-oxo-25-methoxy-24,26-dihydroxy-lanosta-7,9(11)-diene (2), and 3beta-acetyloxy-lucidone H (3). Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D ((1)H-(1)H COSY, HMQC, and HMBC) NMR spectroscopy. All the triterpenoids were in vitro evaluated for their antimicrobial activities against six pathogenic microorganisms. Compounds 1 and 2 exhibited some activities against three Gram positive bacteria with MIC values less than 60 mug/ml.
Lanostanoids with acetylcholinesterase inhibitory activity from the mushroom Haddowia longipes.[Pubmed:25577284]
Phytochemistry. 2015 Feb;110:133-9.
Nine lanostanoids, together with nine known ones, were isolated from the ethyl acetate extract of the fruiting bodies of the mushroom Haddowia longipes. Their structures were elucidated as 11-oxo-Ganoderiol D, lanosta-8-en-7,11-dioxo-3beta-acetyloxy-24,25,26-trihydroxy, lanosta-8-en-7-oxo-3beta-acetyloxy-11beta,24,25,26-tetrahydroxy, lanosta-7,9(11)-dien-3beta-acetyloxy-24,25,26-trihydroxy, lanosta-7,9(11)-dien-3beta-acetyloxy-24,26-dihydroxy-25-methoxy, 11-oxo-lucidadiol, 11beta-hydroxy-lucidadiol, lucidone H and lanosta-7,9(11),24E-trien-3beta-acetyloxy-26,27-dihydroxy by analysing their 1D/2D NMR and MS spectra. In addition, bioassays of inhibitory activity against acetylcholinesterase (AChE) of all compounds showed that thirteen compounds possessed inhibitory activity against AChE with the percentage inhibition ranging from 10.3% to 42.1% when tested at 100 muM.
Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense.[Pubmed:19331378]
J Nat Prod. 2009 May 22;72(5):958-61.
Three new lanostane-type triterpenoids having farnesyl hydroquinone moieties, named ganosinensins A-C (1-3), were isolated from the fruiting body of Ganoderma sinense, together with three known lanostane triterpenes, ganodermanontriol, ganoderiol A, and Ganoderiol D. The structures of compounds 1-3 were determined by spectroscopic data interpretation.
