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Homomangiferin

CAS# 21794-66-1

Homomangiferin

Catalog No. BCN8145----Order now to get a substantial discount!

Product Name & Size Price Stock
Homomangiferin: 5mg Please Inquire In Stock
Homomangiferin: 10mg Please Inquire In Stock
Homomangiferin: 20mg Please Inquire Please Inquire
Homomangiferin: 50mg Please Inquire Please Inquire
Homomangiferin: 100mg Please Inquire Please Inquire
Homomangiferin: 200mg Please Inquire Please Inquire
Homomangiferin: 500mg Please Inquire Please Inquire
Homomangiferin: 1000mg Please Inquire Please Inquire

Quality Control of Homomangiferin

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Chemical structure

Homomangiferin

3D structure

Chemical Properties of Homomangiferin

Cas No. 21794-66-1 SDF Download SDF
PubChem ID 5491388 Appearance Powder
Formula C20H20O11 M.Wt 436.36
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1,6,7-trihydroxy-3-methoxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one
SMILES COC1=C(C(=C2C(=C1)OC3=CC(=C(C=C3C2=O)O)O)O)C4C(C(C(C(O4)CO)O)O)O
Standard InChIKey HDPSXKXQSOVYLL-PQSJUMPYSA-N
Standard InChI InChI=1S/C20H20O11/c1-29-10-4-11-13(15(24)6-2-7(22)8(23)3-9(6)30-11)17(26)14(10)20-19(28)18(27)16(25)12(5-21)31-20/h2-4,12,16,18-23,25-28H,5H2,1H3/t12-,16-,18+,19-,20+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Homomangiferin

The herbs of Mangifera indica

Biological Activity of Homomangiferin

Description1. Homomangiferin shows antitumoural effects against MDA-MB-231 cells.

Homomangiferin Dilution Calculator

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Homomangiferin Molarity Calculator

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Preparing Stock Solutions of Homomangiferin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2917 mL 11.4584 mL 22.9169 mL 45.8337 mL 57.2921 mL
5 mM 0.4583 mL 2.2917 mL 4.5834 mL 9.1667 mL 11.4584 mL
10 mM 0.2292 mL 1.1458 mL 2.2917 mL 4.5834 mL 5.7292 mL
50 mM 0.0458 mL 0.2292 mL 0.4583 mL 0.9167 mL 1.1458 mL
100 mM 0.0229 mL 0.1146 mL 0.2292 mL 0.4583 mL 0.5729 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Homomangiferin

Selective antitumoural action of pressurized mango leaf extracts against minimally and highly invasive breast cancer.[Pubmed:28891568]

Food Funct. 2017 Oct 18;8(10):3610-3620.

Mango leaf tea has been traditionally used by different cultures to reduce inflammation in the body. There is evidence that chronic inflammation increases the risk of cancer. This study investigates the antitumoural effects of pressurized mango leaf extracts on minimally (MCF7) and highly invasive (MDA-MB-231) breast cancer cells as well as on non-tumourigenic cells (MCF10). Extracts showed protective properties against oxidation and cytotoxic effects against breast cancer cell lines, causing minor damage to non-carcinogenic cells. Nonetheless, some selective activity, depending on hormone receptor status, was observed. This was possibly related to the presence of minor compounds. Extracts with high levels of gallotannins showed cytotoxic action against MCF7 cells, while those which had methyl gallate and Homomangiferin as common components were more effective against MDA-MB-231 cells. Therefore, the cytotoxic effect of mango leaf extracts might be attributed to the synergistic effect of different polyphenols and not just to mangiferin on its own as the predominant compound in mango leaves.

Description

Homomangiferin, isolated from the leaves of M. indica L., is mangiferin monomethyl ether. Homomangiferin has important medicinal properties and is widely used to relieve many symptoms, for example coughing and asthma.

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