IsopteleineCAS# 2181-84-2 |
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| Cas No. | 2181-84-2 | SDF | Download SDF |
| PubChem ID | 776150 | Appearance | Powder |
| Formula | C13H11NO3 | M.Wt | 229.23 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 6-methoxy-9-methylfuro[2,3-b]quinolin-4-one | ||
| SMILES | CN1C2=C(C=C(C=C2)OC)C(=O)C3=C1OC=C3 | ||
| Standard InChIKey | XKTZVOMYVJKQTH-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C13H11NO3/c1-14-11-4-3-8(16-2)7-10(11)12(15)9-5-6-17-13(9)14/h3-7H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Dictamnus angustifolius G.Don ex Sweet .
| Description | 1. Isopteleine shows weak cytotoxic activities against human breast cancer cells (MCF7). |
Isopteleine Dilution Calculator
Isopteleine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3624 mL | 21.8122 mL | 43.6243 mL | 87.2486 mL | 109.0608 mL |
| 5 mM | 0.8725 mL | 4.3624 mL | 8.7249 mL | 17.4497 mL | 21.8122 mL |
| 10 mM | 0.4362 mL | 2.1812 mL | 4.3624 mL | 8.7249 mL | 10.9061 mL |
| 50 mM | 0.0872 mL | 0.4362 mL | 0.8725 mL | 1.745 mL | 2.1812 mL |
| 100 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 0.8725 mL | 1.0906 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new quinoline alkaloid from the roots of Dictamnus angustifolius.[Pubmed:24702810]
Chin J Nat Med. 2014 Mar;12(3):222-4.
AIM: To investigate the quinoline alkaloids from the roots of Dictamnus angustifolius G.Don ex Sweet (Rutaceae). METHOD: The quinoline alkaloids were isolated by various column chromatographic methods and their structures were elucidated on the basis of spectral analysis. RESULTS: A new quinoline alkaloid, 5-methoxylrobustine (1), along with five known quinoline alkaloids were obtained, and their structures were identified as dictamnine (2), robustine (3), Isopteleine (4), gamma-fagarine (5), and skimmianine (6). Cytotoxicity testing of these alkaloids showed that all of them had weak cytotoxic activities against human breast cancer cells (MCF7). CONCLUSION: Compound 1 is a new quinoline alkaloid. Alkaloid 3 showed stronger anti-proliferation effect than the other alkaloids.
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