Thalifoline

CAS# 21796-15-6

Thalifoline

2D Structure

Catalog No. BCN3301----Order now to get a substantial discount!

Product Name & Size Price Stock
Thalifoline: 5mg $725 In Stock
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Quality Control of Thalifoline

3D structure

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Thalifoline

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Chemical Properties of Thalifoline

Cas No. 21796-15-6 SDF Download SDF
PubChem ID 89048 Appearance Powder
Formula C11H13NO3 M.Wt 207.2
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-hydroxy-6-methoxy-2-methyl-3,4-dihydroisoquinolin-1-one
SMILES CN1CCC2=CC(=C(C=C2C1=O)O)OC
Standard InChIKey WPKMGEQXTYQXGI-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H13NO3/c1-12-4-3-7-5-10(15-2)9(13)6-8(7)11(12)14/h5-6,13H,3-4H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Thalifoline

The herbs of Thalictrum aquilegifolium

Biological Activity of Thalifoline

Description1. Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
TargetsAntifection

Thalifoline Dilution Calculator

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Thalifoline Molarity Calculator

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Preparing Stock Solutions of Thalifoline

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.8263 mL 24.1313 mL 48.2625 mL 96.5251 mL 120.6564 mL
5 mM 0.9653 mL 4.8263 mL 9.6525 mL 19.305 mL 24.1313 mL
10 mM 0.4826 mL 2.4131 mL 4.8263 mL 9.6525 mL 12.0656 mL
50 mM 0.0965 mL 0.4826 mL 0.9653 mL 1.9305 mL 2.4131 mL
100 mM 0.0483 mL 0.2413 mL 0.4826 mL 0.9653 mL 1.2066 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Thalifoline

Leptopyrine, new alkaloid from Leptopyrum fumarioides L. (Ranunculaceae).[Pubmed:25529023]

Nat Prod Res. 2015;29(9):853-6.

A new type of isoquinoline alkaloid leptopyrine was isolated from the aerial parts of Leptopyrum fumarioides L. (Ranunculaceae) of Mongolian origin. The known alkaloids protopine and Thalifoline were isolated for the first time from this the species. All structures were established by physical and spectral analyses.

New aporphine alkaloids and cytotoxic constituents of Hernandia nymphaeifolia.[Pubmed:9140231]

Planta Med. 1997 Apr;63(2):154-7.

Two new aporphine alkaloids, (+)-N-hydroxyhernangerine (1) and N-formyldehydroovigerine (2) as minor bases, along with four known aporphines, (+)-magnoflorine, (+)-hernovine, (+)-N-methylhernovine, and (+)-laurotetanine, two known isoquinolones, Thalifoline and norThalifoline, and one benzylisoquinoline, (+)-reticuline, have been additionally isolated from the trunk bark of Hernandia nymphaeifolia. The structures of these compounds were elucidated by spectroscopic evidence. Six of the isolated compounds show significant cytotoxic activities (ED50 values < 1 microgram/ml) against P-388, KB16, A549, or HT-29 cell lines.

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