Home >> Research Area >> Scopolamine hydrobromide trihydrate

Scopolamine hydrobromide trihydrate

CAS# 6533-68-2

Scopolamine hydrobromide trihydrate

Catalog No. BCC8188----Order now to get a substantial discount!

Product Name & Size Price Stock
Scopolamine hydrobromide trihydrate: 5mg Please Inquire In Stock
Scopolamine hydrobromide trihydrate: 10mg Please Inquire In Stock
Scopolamine hydrobromide trihydrate: 20mg Please Inquire Please Inquire
Scopolamine hydrobromide trihydrate: 50mg Please Inquire Please Inquire
Scopolamine hydrobromide trihydrate: 100mg Please Inquire Please Inquire
Scopolamine hydrobromide trihydrate: 200mg Please Inquire Please Inquire
Scopolamine hydrobromide trihydrate: 500mg Please Inquire Please Inquire
Scopolamine hydrobromide trihydrate: 1000mg Please Inquire Please Inquire

Quality Control of Scopolamine hydrobromide trihydrate

Number of papers citing our products

Chemical structure

Scopolamine hydrobromide trihydrate

3D structure

Chemical Properties of Scopolamine hydrobromide trihydrate

Cas No. 6533-68-2 SDF Download SDF
PubChem ID 656679 Appearance Powder
Formula C17H28BrNO7 M.Wt 438.3
Type of Compound N/A Storage Desiccate at -20°C
Synonyms Hyoscine hydrobromide trihydrate
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4.O.O.O.Br
Standard InChIKey LACQPOBCQQPVIT-BMGYFXACSA-N
Standard InChI InChI=1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11?,12-,13-,14+,15?,16?;;;;/m1..../s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Scopolamine hydrobromide trihydrate Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Scopolamine hydrobromide trihydrate Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Scopolamine hydrobromide trihydrate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2815 mL 11.4077 mL 22.8154 mL 45.6308 mL 57.0386 mL
5 mM 0.4563 mL 2.2815 mL 4.5631 mL 9.1262 mL 11.4077 mL
10 mM 0.2282 mL 1.1408 mL 2.2815 mL 4.5631 mL 5.7039 mL
50 mM 0.0456 mL 0.2282 mL 0.4563 mL 0.9126 mL 1.1408 mL
100 mM 0.0228 mL 0.1141 mL 0.2282 mL 0.4563 mL 0.5704 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on Scopolamine hydrobromide trihydrate

Scopolamine Hydrobromide is the hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.
Featured Products
New Products
 

References on Scopolamine hydrobromide trihydrate

[An experimental study on the mechanism of bile excretion of the choledochoduodenal junction (author's transl)].[Pubmed:988403]

Nihon Heikatsukin Gakkai Zasshi. 1976 Sep;12(3):139-55.

The present study was undertaken to elucidate the mechanism of bile excretion of the choledochoduodenal junction (ch-d junction) in rabbits, especially regarding it's structural and physiological independence from the duodenum. For this purpose muscular anatomy of the ch-d junction and relationship between the electromygoraphic spike potential of the juncture and the intracholedochal pressure were investigated. 1. There were demonstrated proper circular muscle and proper oblique muscle in the ch-d junction, which appeared independent from the duodenal muscle. There existed A MUSCULAR SPHINCTER at the terminus of the common bile duct, but it's muscle fibers did not appear continuous with the duodenal muscle fibers. 2. The rhythmical changing curve of the intracholedochal pressure was parallel with appearance of the spike potential but had absolutely no correlation with the duodenal one. 3. The attitudes of the ch-d junction and the duodenum to the neural control were compared. The spike generation by Neostigmin METHYLSULFATE WAS EQUALLY OBSERVED IN THE CH-D JUNCTION and the duodenum and the spike inhibition by Hyoscin-N-butylbromide was also equally observed in both of them, SUGGESTING THEIR innervation was probably common.

[Sonographic study of the effect of hyoscin-N-butylbromide on cholecystokinin stimulated gallbladder motility].[Pubmed:6464523]

Z Gastroenterol. 1984 Jun;22(6):305-10.

The influence of the spasmolytic agent Hyoscine-N-butylbromide on the Cholecystokinin induced gallbladder contraction was investigated by ultrasonography in 25 volunteers. Even at a dosage of 0.15 mg/kg i.v. administered Hyoscine-N-butylbromide inhibited significantly the gallbladder emptying. In the investigated dosage range up to 0.6 mg/kg Hyoscine-N-butylbromide a strong response relationship was found. Since after the application of Hyoscine-N-butylbromide 30 min. before Cholecystokinin injection no loss of efficacy was observed, a considerably longer duration of the spasmolytic effect can be assumed. Also the oral form of the spasmolytic (dragees, mean dosage 0.6 mg/kg, application 30 min. before Cholecystokinin) showed a significant inhibition of gallbladder motility.

[The influence of a beta-adrenolytic premedication on cardiovascular parameters and plasma free fatty acids during esophago-gastro-duodenoscopy (author's transl)].[Pubmed:44770]

Wien Med Wochenschr. 1979 Dec 30;199(24):707-12.

Three groups of patients with different premedications were examined for changes of blood pressure, heart rate, ECG and plasma free fatty acid levels during esophago-gastro-duodenoscopy: Group A was premedicated with Bunitrolol, group B was premedicated with Hyoscin-N-butyl-bromide and diazepam, group C was endoscopied without premedication. The pulse rate rose significantly less in group A than in groups A and C; the same phenomenon was observed with regard to the systolic blood pressure. Premature beats occurred in all 3 groups: 32 per cent of the patients in group A, 43 per cent in group B and 60 per cent in group C had at least occasional premature beats; an accumulation of premature beats however occurred significantly less frequently in group A than in groups B or C. A drop of the ST-part of the ECG occurred with about the same frequency in each group. An increase of the plasma free fatty acids, which was noted in groups B and C, could be observed in Group A. A pre-endoscopic medication of beta blocking agents could be a useful measure in patients with labile arterial hypertension, vegatative dysregulation and a hyperkinetic heart syndrome.

Keywords:

Scopolamine hydrobromide trihydrate,6533-68-2,Hyoscine hydrobromide trihydrate,Natural Products, buy Scopolamine hydrobromide trihydrate , Scopolamine hydrobromide trihydrate supplier , purchase Scopolamine hydrobromide trihydrate , Scopolamine hydrobromide trihydrate cost , Scopolamine hydrobromide trihydrate manufacturer , order Scopolamine hydrobromide trihydrate , high purity Scopolamine hydrobromide trihydrate

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: