Lecanoric acidCAS# 480-56-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 480-56-8 | SDF | Download SDF |
PubChem ID | 99613 | Appearance | Powder |
Formula | C16H14O7 | M.Wt | 318.3 |
Type of Compound | Phenols | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid | ||
SMILES | CC1=CC(=CC(=C1C(=O)OC2=CC(=C(C(=C2)C)C(=O)O)O)O)O | ||
Standard InChIKey | HEMSJKZDHNSSEW-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C16H14O7/c1-7-3-9(17)5-11(18)14(7)16(22)23-10-4-8(2)13(15(20)21)12(19)6-10/h3-6,17-19H,1-2H3,(H,20,21) | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. Lecanoric acid analogues antagonizes several enzymic and cellular effects of the tumour promoter. 2. Lecanoric acid analogues inhibits prostaglandin synthetase and delayed-type hypersensitivity responses against sheep red blood cells in mice. 3. Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 ug/ml conc. shows high growth stimulating activity in terms of increased dry matter of biomass (56.08 mg) of L. casei. |
Targets | GSK-3 | P450 (e.g. CYP17) |
Lecanoric acid Dilution Calculator
Lecanoric acid Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.1417 mL | 15.7085 mL | 31.4169 mL | 62.8338 mL | 78.5423 mL |
5 mM | 0.6283 mL | 3.1417 mL | 6.2834 mL | 12.5668 mL | 15.7085 mL |
10 mM | 0.3142 mL | 1.5708 mL | 3.1417 mL | 6.2834 mL | 7.8542 mL |
50 mM | 0.0628 mL | 0.3142 mL | 0.6283 mL | 1.2567 mL | 1.5708 mL |
100 mM | 0.0314 mL | 0.1571 mL | 0.3142 mL | 0.6283 mL | 0.7854 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Retrorsine
Catalog No.:BCN2119
CAS No.:480-54-6
- Hydrangenol
Catalog No.:BCN5561
CAS No.:480-47-7
- Acacetin
Catalog No.:BCN5560
CAS No.:480-44-4
- Isosakuranetin
Catalog No.:BCN5559
CAS No.:480-43-3
- Naringenin
Catalog No.:BCN5558
CAS No.:480-41-1
- Chrysin
Catalog No.:BCN5557
CAS No.:480-40-0
- Pinocembrin
Catalog No.:BCN5556
CAS No.:480-39-7
- Pinostrobin
Catalog No.:BCN5555
CAS No.:480-37-5
- Linarin
Catalog No.:BCN5554
CAS No.:480-36-4
- Eugenin
Catalog No.:BCN2921
CAS No.:480-34-2
- Mellein
Catalog No.:BCN4785
CAS No.:480-33-1
- Orobol
Catalog No.:BCN5553
CAS No.:480-23-9
- Orsellinic acid
Catalog No.:BCN6574
CAS No.:480-64-8
- 2',4',6'-Trihydroxyacetophenone
Catalog No.:BCN3996
CAS No.:480-66-0
- Jaconine
Catalog No.:BCN2089
CAS No.:480-75-1
- Jacoline
Catalog No.:BCN2088
CAS No.:480-76-2
- Platyphylline
Catalog No.:BCN2115
CAS No.:480-78-4
- Integerrimine
Catalog No.:BCN2131
CAS No.:480-79-5
- Seneciphylline
Catalog No.:BCN5563
CAS No.:480-81-9
- Indicine
Catalog No.:BCN1995
CAS No.:480-82-0
- Echinatine
Catalog No.:BCN1968
CAS No.:480-83-1
- Retronecine
Catalog No.:BCN2034
CAS No.:480-85-3
- Retusine
Catalog No.:BCN2123
CAS No.:480-86-4
- Dicrotaline
Catalog No.:BCN2079
CAS No.:480-87-5
Growth promoting effects of some lichen metabolites on probiotic bacteria.[Pubmed:25328204]
J Food Sci Technol. 2014 Oct;51(10):2624-31.
In the present study, the extract of four natural lichen species Canoparmelia eruptens, Everniastrum cirrhatum, Parmotrema austrosinense and Rimelia cetrata were studied for the source of natural antioxidant and their purified secondary metabolites were evaluated for growth promoting effects on probiotic bacteria Lactobacillus casei. The methanolic fraction of lichen species showed moderate to high antioxidant activity in the order P. austrosinense > E. cirrhatum > C. eruptens > R. cetrata. The lichen metabolites showed antioxidant activity with an IC50 values (mug/ml); Lecanoric acid 79-95, salazinic 88-108, atranorin 100-116 and consalazinic acid 119-125. As far as the growth promoting effects of lichen metabolites on L. casei is concerned, Lecanoric acid at 100 mug/ml conc. showed high growth stimulating activity in terms of increased dry matter of biomass (56.08 mg) of L. casei. Other lichen metabolites; salazinic acid, atranorin and consalazinic acid produced relatively less dry biomass 43.98 mg, 41.1 mg, 40.68 mg, respectively. However, standard antioxidants butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and Trolox after 36 h produced 39.04-47.81 mg dry biomass. At lower pH the growth promoting activity of lichen metabolites was found stable.
Inhibition of histidine decarboxylase and tumour promoter-induced arachidonic acid release by lecanoric acid analogues.[Pubmed:6404261]
Biochem Biophys Res Commun. 1983 Feb 10;110(3):733-9.
Lecanoric acid analogues containing benzanilide structure inhibited histidine decarboxylase and arachidonic acid release from the cell membrane phospholipids induced by a tumour promoter, 12-O-tetradecanoylphorbol-13-acetate. But they did not inhibit cellular binding of phorbol-12,13-dibutylate. Lecanoric acid analogues also inhibited prostaglandin synthetase and delayed-type hypersensitivity responses against sheep red blood cells in mice. Thus, Lecanoric acid analogues antagonized several enzymic and cellular effects of the tumour promoter.