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N-Methylcorydalmine

CAS# 81010-29-9

N-Methylcorydalmine

2D Structure

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Quality Control of N-Methylcorydalmine

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N-Methylcorydalmine

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Chemical Properties of N-Methylcorydalmine

Cas No. 81010-29-9 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C21H25NO4 M.Wt 355.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of N-Methylcorydalmine

The roots of Stephania elegans

Biological Activity of N-Methylcorydalmine

DescriptionN-Methylcorydalmine may exhibit significant anti-hypoxia activity.
In vitro

Chemical constituents from rhizome of Menispermum dauricum and their anti-hypoxic activities.[Pubmed: 30989885]

Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(4):723-729.


METHODS AND RESULTS:
To study the chemical constituents from the rhizome of Menispermum dauricum,fifteen compounds, N-Methylcorydalmine( 1),thalifoline( 2),stepholidine( 3),acutumine( 4),daurisoline( 5),acutumidine( 6),dauricicoline( 7),bianfugecine( 8),6-O-demethylmenisporphine( 9),bianfugedine( 10),dauricoside( 11),eleutheroside D( 12),aristolactone( 13),aristoloterpenateⅠ( 14) and aristolochic acid( 15) were isolated from 75% ethanol extract of Menispermi Rhizoma by using thin layer chromatography and column chromatography methods. Their structures were identified based on their physicochemical properties and spectral data. Among them,compounds 12-15 were obtained from the genus Menispermum for the first time. Six alkaloids with higher contents were subjected to evaluate the anti-hypoxic activities by using MTT method.
CONCLUSIONS:
As a result,six alkaloids exhibited significant anti-hypoxia activities.

N-Methylcorydalmine Dilution Calculator

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N-Methylcorydalmine Molarity Calculator

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Preparing Stock Solutions of N-Methylcorydalmine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8137 mL 14.0687 mL 28.1373 mL 56.2746 mL 70.3433 mL
5 mM 0.5627 mL 2.8137 mL 5.6275 mL 11.2549 mL 14.0687 mL
10 mM 0.2814 mL 1.4069 mL 2.8137 mL 5.6275 mL 7.0343 mL
50 mM 0.0563 mL 0.2814 mL 0.5627 mL 1.1255 mL 1.4069 mL
100 mM 0.0281 mL 0.1407 mL 0.2814 mL 0.5627 mL 0.7034 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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