EpischisandroneCAS# 98619-26-2 |
- Schisandrone
Catalog No.:BCN3316
CAS No.:98619-25-1
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 98619-26-2 | SDF | Download SDF |
| PubChem ID | 14078175 | Appearance | Powder |
| Formula | C21H24O5 | M.Wt | 356.4 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-(3,4-dimethoxyphenyl)-7-hydroxy-6-methoxy-2,3-dimethyl-3,4-dihydro-2H-naphthalen-1-one | ||
| SMILES | CC1C(C(=O)C2=CC(=C(C=C2C1C3=CC(=C(C=C3)OC)OC)OC)O)C | ||
| Standard InChIKey | DRKPZVVNEGETTG-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C21H24O5/c1-11-12(2)21(23)15-9-16(22)18(25-4)10-14(15)20(11)13-6-7-17(24-3)19(8-13)26-5/h6-12,20,22H,1-5H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| In vitro | Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens.[Pubmed: 23883077 ]Pharm Biol. 2013 Sep;51(9):1204-7.The diethyl ether extract of the stems of Schisandra pubescens Hemsl. et Wils. (Schisandraceae) was found to exhibit cytotoxic activity in vitro. However, investigations of the bioactive constituents of this plant have been very limited.
Elucidation of the cytotoxic constituents of S. pubescens was performed.
|
| Structure Identification | Chem Pharm Bull (Tokyo). 2009 Apr;57(4):405-7.Two new lignans from Schisandra henryi.[Pubmed: 19336937]
|
Epischisandrone Dilution Calculator
Epischisandrone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.8058 mL | 14.0292 mL | 28.0584 mL | 56.1167 mL | 70.1459 mL |
| 5 mM | 0.5612 mL | 2.8058 mL | 5.6117 mL | 11.2233 mL | 14.0292 mL |
| 10 mM | 0.2806 mL | 1.4029 mL | 2.8058 mL | 5.6117 mL | 7.0146 mL |
| 50 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.1223 mL | 1.4029 mL |
| 100 mM | 0.0281 mL | 0.1403 mL | 0.2806 mL | 0.5612 mL | 0.7015 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- 1,2-Epoxy-10(14)-furanogermacren-6-one
Catalog No.:BCN8891
CAS No.:383368-24-9
- Bruceantinol B
Catalog No.:BCN8890
CAS No.:1822332-33-1
- Notoptol
Catalog No.:BCN8889
CAS No.:88206-49-9
- 2-Methoxyfuranoguaia-9-ene-8-one
Catalog No.:BCN8888
CAS No.:88010-62-2
- Isovalerylshikonin
Catalog No.:BCN8887
CAS No.:52387-14-1
- Isolappaol A
Catalog No.:BCN8886
CAS No.:131400-96-9
- Pieceid-2''-O-gallate
Catalog No.:BCN8885
CAS No.:105304-51-6
- 3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside
Catalog No.:BCN8884
CAS No.:51768-39-9
- Geoside
Catalog No.:BCN8882
CAS No.:585-90-0
- Trachelogenin 4'-O-beta-gentiobioside
Catalog No.:BCN8881
CAS No.:106647-13-6
- Tigloylgomisin O
Catalog No.:BCN8880
CAS No.:130855-74-2
- Gypenoside XIII
Catalog No.:BCN8927
CAS No.:80325-22-0
- Andrographidine A
Catalog No.:BCN8893
CAS No.:113963-37-4
- Quercetin 7-O-(6''-O-malonyl)-beta-D-glucoside
Catalog No.:BCN8894
CAS No.:98767-37-4
- Prionanthoside
Catalog No.:BCN8895
CAS No.:161842-81-5
- N-Methylcorydalmine
Catalog No.:BCN8896
CAS No.:81010-29-9
- 6'-Feruloylnodakenin
Catalog No.:BCN8897
CAS No.:131623-14-8
- 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol
Catalog No.:BCN8898
CAS No.:913643-31-9
- [(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one
Catalog No.:BCN8899
CAS No.:75412-95-2
- Cichoriin
Catalog No.:BCN8900
CAS No.:531-58-8
- Spinacetin
Catalog No.:BCN8901
CAS No.:3153-83-1
- (E)-6-O-(p-coumaroyl)scandoside methyl ester
Catalog No.:BCN8902
CAS No.:83946-90-1
- 3-Acetyl-ginsenoside F1
Catalog No.:BCN8903
CAS No.:1881225-08-6
- Nortrachelogenin-8'-O-beta-glucoside
Catalog No.:BCN8904
CAS No.:858127-38-5
Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens.[Pubmed:23883077]
Pharm Biol. 2013 Sep;51(9):1204-7.
CONTEXT: The diethyl ether extract of the stems of Schisandra pubescens Hemsl. et Wils. (Schisandraceae) was found to exhibit cytotoxic activity in vitro. However, investigations of the bioactive constituents of this plant have been very limited. OBJECTIVE: Elucidation of the cytotoxic constituents of S. pubescens was performed. METHODS: Repeated silica gel column chromatography and preparative TLC were used for the chemical investigation of the diethyl ether extract of S. pubescens stems. All isolates were evaluated for their in vitro cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines. RESULTS: Nine known compounds were obtained, including four lignans, Epischisandrone (1), tigloylgomisin P (2), cagayanone (3) and (-)-gomisin L(2) (4), together with five triterpenoids, micranoic acid B (5), lancifodilactone H (6), coccinic acid (7), schisanlactone B (8) and anwuweizonic acid (9). Compounds 2-6 and 8 showed moderate to marginal cytotoxicity, with GI(5)(0) values of 11.83-35.65 muM. CONCLUSION: The isolation of 1-9 from S. pubescens and the cytotoxicities of 3-6 are first reported. Compounds 2-6 and 8 could be the active principles responsible for the anticancer effects of S. pubescens.
Two new lignans from Schisandra henryi.[Pubmed:19336937]
Chem Pharm Bull (Tokyo). 2009 Apr;57(4):405-7.
Two new lignans, henricines A (1) and B (2), were isolated along with the eight known lignans, ganshisandrine (3), wulignan A(2) (4), epiwulignan A(1) (5), deoxyschisandrin (6), wulignan A(1) (7), Epischisandrone (8), schisantherin A (9), and schisandrol A (10), from the stems of Schisandra henryi. The structures of the new compounds were elucidated based on the spectral analysis, including 1D and 2D NMR experiments.
