Rebaudioside F

CAS# 438045-89-7

Rebaudioside F

Catalog No. BCN8908----Order now to get a substantial discount!

Product Name & Size Price Stock
Rebaudioside F: 5mg $265 In Stock
Rebaudioside F: 10mg Please Inquire In Stock
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Quality Control of Rebaudioside F

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Chemical structure

Rebaudioside F

3D structure

Chemical Properties of Rebaudioside F

Cas No. 438045-89-7 SDF Download SDF
PubChem ID 72941817 Appearance White powder
Formula C43H68O22 M.Wt 937.0
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in methan
Chemical Name [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
SMILES CC12CCCC(C1CCC34C2CCC(C3)(C(=C)C4)OC5C(C(C(C(O5)CO)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(CO7)O)O)O)(C)C(=O)OC8C(C(C(C(O8)CO)O)O)O
Standard InChIKey HYLAUKAHEAUVFE-AVBZULRRSA-N
Standard InChI InChI=1S/C43H68O22/c1-17-11-42-9-5-22-40(2,7-4-8-41(22,3)39(57)64-37-32(56)29(53)26(50)20(13-45)60-37)23(42)6-10-43(17,16-42)65-38-34(63-35-30(54)24(48)18(47)15-58-35)33(27(51)21(14-46)61-38)62-36-31(55)28(52)25(49)19(12-44)59-36/h18-38,44-56H,1,4-16H2,2-3H3/t18-,19-,20-,21-,22+,23+,24+,25-,26-,27-,28+,29+,30-,31-,32-,33+,34-,35+,36+,37+,38+,40-,41-,42-,43+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rebaudioside F

The leaves of Stevia rebaudiana Bertoni.

Protocol of Rebaudioside F

Structure Identification
Phytochemistry. 2002 Feb;59(4):367-70.

Rebaudioside F, a diterpene glycoside from Stevia rebaudiana.[Pubmed: 11830149 ]


METHODS AND RESULTS:
The sweet diterpenoid glycoside, Rebaudioside F, was isolated from leaves of a high rebaudioside C producing line of Stevia rebaudiana, and its structure was established by chemical and spectral studies.

FEBS Open Bio. 2016 Aug 30;6(9):937-44.

Gene transcription and steviol glycoside accumulation in Stevia rebaudiana under polyethylene glycol-induced drought stress in greenhouse cultivation.[Pubmed: 27642557]

Stevia rebaudiana is a sweet herb of the Astraceae family, which is cultivated for the natural sweeteners it contains. The aim of this study was to assess the effect of drought, simulated by the application of polyethylene glycol (5%, 10%, and 15% w/v), on the content of steviol glycosides (SVglys) and transcription levels of six genes involved in the biosynthesis of these natural sweeteners.
METHODS AND RESULTS:
The transcription levels of ent-kaurene synthase, ent-kaurene oxidase, ent-kaurenoic acid hydroxylase, and three UDP-dependent glycosyltransferases, UGT85C2,UGT74G1 and UGT76G1 were downregulated under polyethylene glycol treatment. Polyethylene glycol treatment significantly decreased the amount of stevioside, rebaudioside A, rebaudioside B, rebaudioside C and Rebaudioside F, steviolbioside, dulcoside A, rubusoside, and total SVglys. These results strongly suggest a close relationship of SVglys content with the transcription of genes involved in the SVglys biosynthesis pathway. Comparing the observations of the present study with other reports provided the knowledge that the Stevia response to drought stress can be influenced by different environmental and experimental factors, in addition to intensity of drought stress.
CONCLUSIONS:
In conclusion, these results strongly suggest that polyethylene glycol-induced drought stress has a negative effect on the content of SVglys and transcription of SVglys biosynthetic genes and that this should be investigated further. We recommend that sufficient irrigation of Stevia is required to obtain a high content of SVglys.

Rebaudioside F Dilution Calculator

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Rebaudioside F Molarity Calculator

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Preparing Stock Solutions of Rebaudioside F

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0672 mL 5.3362 mL 10.6724 mL 21.3447 mL 26.6809 mL
5 mM 0.2134 mL 1.0672 mL 2.1345 mL 4.2689 mL 5.3362 mL
10 mM 0.1067 mL 0.5336 mL 1.0672 mL 2.1345 mL 2.6681 mL
50 mM 0.0213 mL 0.1067 mL 0.2134 mL 0.4269 mL 0.5336 mL
100 mM 0.0107 mL 0.0534 mL 0.1067 mL 0.2134 mL 0.2668 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rebaudioside F

Rebaudioside F, a diterpene glycoside from Stevia rebaudiana.[Pubmed:11830149]

Phytochemistry. 2002 Feb;59(4):367-70.

The sweet diterpenoid glycoside, Rebaudioside F, was isolated from leaves of a high rebaudioside C producing line of Stevia rebaudiana, and its structure was established by chemical and spectral studies.

Description

Rebaudioside F is a steviol glycoside isolated from Stevia rebaudiana leaves.

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