Dichotomine B

CAS# 755036-41-0

Dichotomine B

2D Structure

Catalog No. BCN8913----Order now to get a substantial discount!

Product Name & Size Price Stock
Dichotomine B: 5mg $426 In Stock
Dichotomine B: 10mg Please Inquire In Stock
Dichotomine B: 20mg Please Inquire Please Inquire
Dichotomine B: 50mg Please Inquire Please Inquire
Dichotomine B: 100mg Please Inquire Please Inquire
Dichotomine B: 200mg Please Inquire Please Inquire
Dichotomine B: 500mg Please Inquire Please Inquire
Dichotomine B: 1000mg Please Inquire Please Inquire

Quality Control of Dichotomine B

3D structure

Package In Stock

Dichotomine B

Number of papers citing our products

Chemical Properties of Dichotomine B

Cas No. 755036-41-0 SDF Download SDF
PubChem ID 11173314 Appearance Powder
Formula C14H12N2O4 M.Wt 272.3
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-[(1R)-1,2-dihydroxyethyl]-9H-pyrido[3,4-b]indole-3-carboxylic acid
SMILES C1=CC=C2C(=C1)C3=CC(=NC(=C3N2)C(CO)O)C(=O)O
Standard InChIKey PKSXEHHRROSXPR-NSHDSACASA-N
Standard InChI InChI=1S/C14H12N2O4/c17-6-11(18)13-12-8(5-10(16-13)14(19)20)7-3-1-2-4-9(7)15-12/h1-5,11,15,17-18H,6H2,(H,19,20)/t11-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Dichotomine B

The herbs of Stellaria dichotoma

Protocol of Dichotomine B

Structure Identification
J Nat Prod. 2004 Sep;67(9):1464-9.

Structures of new beta-carboline-type alkaloids with antiallergic effects from Stellaria dichotoma(1,2).[Pubmed: 21090796 ]

The aqueous ethanolic extract from the roots of Stellaria dichotoma showed an antiallergic effect on ear passive cutaneous anaphylaxis (PCA) reaction in mice (in vivo) and inhibitory activity on the release of beta-hexosaminidase in RBL-2H3 cells (in vitro).
METHODS AND RESULTS:
From the aqueous ethanolic extract, new beta-carboline-type alkaloids, dichotomine A (1), Dichotomine B (2), dichotomine C (3), and dichotomine D (4) and dichotomides I (5) and II (6), were isolated. The structures of the new constituents (1-6) were determined on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.
CONCLUSIONS:
The effects of the isolated constituents on the release of beta-hexosaminidase in RBL-2H3 cells were examined, and 3 was found to show inhibitory activity (IC(50) = 62 microM). Moreover, 3 also inhibited the releases of antigen-IgE-mediated TNF-alpha and IL-4 (19 and 15 microM, respectively) in RBL-2H3 cells, both of which participate in the late phase of type I allergic reactions.

Dichotomine B Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Dichotomine B Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Dichotomine B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6724 mL 18.3621 mL 36.7242 mL 73.4484 mL 91.8105 mL
5 mM 0.7345 mL 3.6724 mL 7.3448 mL 14.6897 mL 18.3621 mL
10 mM 0.3672 mL 1.8362 mL 3.6724 mL 7.3448 mL 9.1811 mL
50 mM 0.0734 mL 0.3672 mL 0.7345 mL 1.469 mL 1.8362 mL
100 mM 0.0367 mL 0.1836 mL 0.3672 mL 0.7345 mL 0.9181 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

Keywords:

Dichotomine B,755036-41-0,Natural Products, buy Dichotomine B , Dichotomine B supplier , purchase Dichotomine B , Dichotomine B cost , Dichotomine B manufacturer , order Dichotomine B , high purity Dichotomine B

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: