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N,N,N-Trimethyl-2-aminoethylphosphonate

CAS# 14596-57-7

N,N,N-Trimethyl-2-aminoethylphosphonate

2D Structure

Catalog No. BCN1560----Order now to get a substantial discount!

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N,N,N-Trimethyl-2-aminoethylphosphonate: 10mg Please Inquire In Stock
N,N,N-Trimethyl-2-aminoethylphosphonate: 20mg Please Inquire Please Inquire
N,N,N-Trimethyl-2-aminoethylphosphonate: 50mg Please Inquire Please Inquire
N,N,N-Trimethyl-2-aminoethylphosphonate: 100mg Please Inquire Please Inquire
N,N,N-Trimethyl-2-aminoethylphosphonate: 200mg Please Inquire Please Inquire
N,N,N-Trimethyl-2-aminoethylphosphonate: 500mg Please Inquire Please Inquire
N,N,N-Trimethyl-2-aminoethylphosphonate: 1000mg Please Inquire Please Inquire

Quality Control of N,N,N-Trimethyl-2-aminoethylphosphonate

3D structure

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N,N,N-Trimethyl-2-aminoethylphosphonate

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Chemical Properties of N,N,N-Trimethyl-2-aminoethylphosphonate

Cas No. 14596-57-7 SDF Download SDF
PubChem ID 4242130 Appearance Powder
Formula C5H14NO3P M.Wt 167.14
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name hydroxy-[2-(trimethylazaniumyl)ethyl]phosphinate
SMILES C[N+](C)(C)CCP(=O)(O)[O-]
Standard InChIKey VCANKBLUHKRQLL-UHFFFAOYSA-N
Standard InChI InChI=1S/C5H14NO3P/c1-6(2,3)4-5-10(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of N,N,N-Trimethyl-2-aminoethylphosphonate

The Anthopleura xanthogrammica

Biological Activity of N,N,N-Trimethyl-2-aminoethylphosphonate

DescriptionStandard reference
In vitro

Effect of a phosphonic acid analog of choline phosphate on phospholipid metabolism in Tetrahymena.[Reference: WebLink]

Archives of Biochemistry & Biophysics, 1982 , 213 (2) :595-601


METHODS AND RESULTS:
When Tetrahymena thermophila is grown on a medium containing increasing concentrations of N,N,N-Trimethyl-2-aminoethylphosphonate (TMAEP), up to 60% of the choline phosphate in phosphatidylcholine is replaced by the phosphonic acid. There is an increase in the relative amount of quaternary ammonium-containing lipid (phosphatidylcholine plus TMAEP-lipid) at the expense of phosphatidylethanolamine. There is no effect of the TMAEP on either 2-aminoethylphosphonolipid levels or on de novo 2-aminoethylphosphonate synthesis.
CONCLUSIONS:
Higher levels of TMAEP in the medium (25 and 50 mm) lead to decreased growth of Tetrahymena and to an abnormal cell morphology.

N,N,N-Trimethyl-2-aminoethylphosphonate Dilution Calculator

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N,N,N-Trimethyl-2-aminoethylphosphonate Molarity Calculator

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Preparing Stock Solutions of N,N,N-Trimethyl-2-aminoethylphosphonate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.983 mL 29.915 mL 59.8301 mL 119.6602 mL 149.5752 mL
5 mM 1.1966 mL 5.983 mL 11.966 mL 23.932 mL 29.915 mL
10 mM 0.5983 mL 2.9915 mL 5.983 mL 11.966 mL 14.9575 mL
50 mM 0.1197 mL 0.5983 mL 1.1966 mL 2.3932 mL 2.9915 mL
100 mM 0.0598 mL 0.2992 mL 0.5983 mL 1.1966 mL 1.4958 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on N,N,N-Trimethyl-2-aminoethylphosphonate

Effect of a phosphonic acid analog of choline phosphate on phospholipid metabolism in Tetrahymena.

Archives of Biochemistry & Biophysics, 1982 , 213 (2) :595-601

When Tetrahymena thermophila is grown on a medium containing increasing concentrations of N,N,N-Trimethyl-2-aminoethylphosphonate (TMAEP), up to 60% of the choline phosphate in phosphatidylcholine is replaced by the phosphonic acid. There is an increase in the relative amount of quaternary ammonium-containing lipid (phosphatidylcholine plus TMAEP-lipid) at the expense of phosphatidylethanolamine. There is no effect of the TMAEP on either 2-aminoethylphosphonolipid levels or on de novo 2-aminoethylphosphonate synthesis. Higher levels of TMAEP in the medium (25 and 50 mm) lead to decreased growth of Tetrahymena and to an abnormal cell morphology.

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