Laccaic acid E

CAS# 14597-16-1

Laccaic acid E

Catalog No. BCN1807----Order now to get a substantial discount!

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Chemical structure

Laccaic acid E

3D structure

Chemical Properties of Laccaic acid E

Cas No. 14597-16-1 SDF Download SDF
PubChem ID 15045881 Appearance Yellow powder
Formula C24H17NO11 M.Wt 495.40
Type of Compound Anthraquinones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-[5-(2-aminoethyl)-2-hydroxyphenyl]-3,5,6,8-tetrahydroxy-9,10-dioxoanthracene-1,2-dicarboxylic acid
SMILES C1=CC(=C(C=C1CCN)C2=C(C3=C(C(=C2O)O)C(=O)C4=CC(=C(C(=C4C3=O)C(=O)O)C(=O)O)O)O)O
Standard InChIKey QPCFHDQETKDGHT-UHFFFAOYSA-N
Standard InChI InChI=1S/C24H17NO11/c25-4-3-7-1-2-10(26)8(5-7)13-20(30)17-16(22(32)21(13)31)18(28)9-6-11(27)14(23(33)34)15(24(35)36)12(9)19(17)29/h1-2,5-6,26-27,30-32H,3-4,25H2,(H,33,34)(H,35,36)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Laccaic acid E

Description1. Laccaic acids A, B and E as coloring matters in the examined preparations of lac-dye.

Laccaic acid E Dilution Calculator

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Laccaic acid E Molarity Calculator

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Preparing Stock Solutions of Laccaic acid E

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0186 mL 10.0929 mL 20.1857 mL 40.3714 mL 50.4643 mL
5 mM 0.4037 mL 2.0186 mL 4.0371 mL 8.0743 mL 10.0929 mL
10 mM 0.2019 mL 1.0093 mL 2.0186 mL 4.0371 mL 5.0464 mL
50 mM 0.0404 mL 0.2019 mL 0.4037 mL 0.8074 mL 1.0093 mL
100 mM 0.0202 mL 0.1009 mL 0.2019 mL 0.4037 mL 0.5046 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Laccaic acid E

[Analysis of lac color in diets and feces of rats for toxicity studies].[Pubmed:12092412]

Shokuhin Eiseigaku Zasshi. 2002 Apr;43(2):110-3.

An analytical method was developed for lac color in diets fed to rats and in the feces, and the contents of lac color were determined. After lac color was extracted with 0.05% sodium carbonate and 50% ethanol containing 0.02% sodium lauryl sulfate from the diets and feces, the extracted color solutions were analyzed by HPLC. The recoveries of lac color from diets spiked at 1.25, 5.00% and that from feces spiked at 5.00% were 85.6, 93.4% and 69.5%, respectively. Contents of lac color in diets prepared to contain 1.25 and 5.00% were 1.1 and 5.2%, and dose levels were confirmed by these results. Contents of lac color in feces of male and female rats given lac color were 127.8 mg/g and 138.6 mg/g, respectively. By comparing the HPLC chromatograms of laccaic acids in the diet with those in feces of rats, laccaic acid A, B, C and E were detected in both, and their content ratios were approximately determined.

Identification of anthraquinone coloring matters in natural red dyes by electrospray mass spectrometry coupled to capillary electrophoresis.[Pubmed:14696204]

J Mass Spectrom. 2003 Dec;38(12):1252-8.

Capillary electrophoresis with UV/visible diode-array detection (DAD) and electrospray mass spectrometric (ESI-MS) detection were used for the identification of anthraquinone color components of cochineal, lac-dye and madder, natural red dyestuffs often used by ancient painters. For the purpose of such analysis, ESI-MS was found to be a much more appropriate detection technique than DAD one owing to its higher sensitivity (detection limits in the range 0.1-0.5 micro g ml(-1)) and selectivity. The method developed made it possible to identify unequivocally carminic acid and laccaic acids A, B and E as coloring matters in the examined preparations of cochineal and lac-dye, respectively. In madder, European Rubia tinctorum, alizarin and purpurin were found. The method allows the rapid, direct and straightforward identification and quantification of components of natural products used in art and could be very helpful in restoration and conservation procedures.

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