Niazinin

CAS# 147821-57-6

Niazinin

Catalog No. BCN7623----Order now to get a substantial discount!

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Quality Control of Niazinin

Number of papers citing our products

Chemical structure

Niazinin

3D structure

Chemical Properties of Niazinin

Cas No. 147821-57-6 SDF Download SDF
PubChem ID 10088810 Appearance Oil
Formula C15H21NO6S M.Wt 343.39
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name O-methyl N-[[4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]methyl]carbamothioate
SMILES CC1C(C(C(C(O1)OC2=CC=C(C=C2)CNC(=S)OC)O)O)O
Standard InChIKey ZOIAMMQYAZSWRX-CNJBRALLSA-N
Standard InChI InChI=1S/C15H21NO6S/c1-8-11(17)12(18)13(19)14(21-8)22-10-5-3-9(4-6-10)7-16-15(23)20-2/h3-6,8,11-14,17-19H,7H2,1-2H3,(H,16,23)/t8-,11-,12+,13+,14-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Niazinin

The leaves of Moringa oleifera Lam.

Biological Activity of Niazinin

Description1. Niazinin shows antileishmanial activity against promastigotes of Leishmania donavani, with an IC50 value of 5.25 microM.
TargetsAntifection

Niazinin Dilution Calculator

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Niazinin Molarity Calculator

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Preparing Stock Solutions of Niazinin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9121 mL 14.5607 mL 29.1214 mL 58.2428 mL 72.8035 mL
5 mM 0.5824 mL 2.9121 mL 5.8243 mL 11.6486 mL 14.5607 mL
10 mM 0.2912 mL 1.4561 mL 2.9121 mL 5.8243 mL 7.2804 mL
50 mM 0.0582 mL 0.2912 mL 0.5824 mL 1.1649 mL 1.4561 mL
100 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.5824 mL 0.728 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Niazinin

Antileishmanial compounds from Moringa oleifera Lam.[Pubmed:24873031]

Z Naturforsch C. 2014 Mar-Apr;69(3-4):110-6.

The antileishmanial activity of extracts and phytoconstituents of Moringa oleifera Lam. was investigated in vitro against promastigotes of Leishmania donavani. The 70% ethanolic extract of roots and the methanolic extract of leaves showed moderate inhibitory activity with IC50 values of 83.0 microg/ml and 47.5 microg/ml, respectively. Antileishmanial activity of the methanolic extract of leaves increased upon fractionation, as its ethyl acetate fraction was found to be more active with an IC50 value of 27.5 microg/ml. The most active antileishmanial compound Niazinin, a thiocarbamate glycoside isolated from this fraction, showed an IC50 value of 5.25 microM. Results presented in this study indicate that extracts from M. oleifera may be developed as an adjuvant therapy for the treatment of leishmaniasis.

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