Pachyaximine ACAS# 128255-08-3 |
Quality Control & MSDS
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| Cas No. | 128255-08-3 | SDF | Download SDF |
| PubChem ID | 44358210 | Appearance | Powder |
| Formula | C24H41NO | M.Wt | 359.6 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1S)-1-[(3S,8S,9S,10R,13S,14S,17S)-3-methoxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N,N-dimethylethanamine | ||
| SMILES | CC(C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC)C)C)N(C)C | ||
| Standard InChIKey | ZTNBSFMIFOLVCM-MCTVSQGJSA-N | ||
| Standard InChI | InChI=1S/C24H41NO/c1-16(25(4)5)20-9-10-21-19-8-7-17-15-18(26-6)11-13-23(17,2)22(19)12-14-24(20,21)3/h7,16,18-22H,8-15H2,1-6H3/t16-,18-,19-,20+,21-,22-,23-,24+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Pachysandra axillaris
| Description | 1. Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. 2. (-)-Pachyaximine A demonstrates significant activity as antiestrogen binding site (AEBS)-inhibitory agents, and potentiates significantly the antiestrogenic effect mediated by tamoxifen in cultured Ishikawa cells. |
| Targets | Estrogen receptor | Antifection | Progestogen receptor |
Pachyaximine A Dilution Calculator
Pachyaximine A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.7809 mL | 13.9043 mL | 27.8087 mL | 55.6174 mL | 69.5217 mL |
| 5 mM | 0.5562 mL | 2.7809 mL | 5.5617 mL | 11.1235 mL | 13.9043 mL |
| 10 mM | 0.2781 mL | 1.3904 mL | 2.7809 mL | 5.5617 mL | 6.9522 mL |
| 50 mM | 0.0556 mL | 0.2781 mL | 0.5562 mL | 1.1123 mL | 1.3904 mL |
| 100 mM | 0.0278 mL | 0.139 mL | 0.2781 mL | 0.5562 mL | 0.6952 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Anti-bacterial alkaloids of Saracococca saligna.[Pubmed:16431389]
Pak J Pharm Sci. 2005 Apr;18(2):3-5.
The crude ethanolic extract of Saracococca saligna was found to be cytotoxic and antibacterial but produced no platelet aggregation induced by ADP. Antibacterial activity of two known alkaloid, pachyaximine-A and saracodine was determined. Pachyaximine-A possessed significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. Saracodme showed moderate activity against Staphylococcus pyrogenes, Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae, Shigella boydii and Klebsiella pneumoniae.
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