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Pachyaximine A

CAS# 128255-08-3

Pachyaximine A

Catalog No. BCN6152----Order now to get a substantial discount!

Product Name & Size Price Stock
Pachyaximine A: 5mg $828 In Stock
Pachyaximine A: 10mg Please Inquire In Stock
Pachyaximine A: 20mg Please Inquire Please Inquire
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Pachyaximine A: 500mg Please Inquire Please Inquire
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Quality Control of Pachyaximine A

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Chemical structure

Pachyaximine A

3D structure

Chemical Properties of Pachyaximine A

Cas No. 128255-08-3 SDF Download SDF
PubChem ID 44358210 Appearance Powder
Formula C24H41NO M.Wt 359.6
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S)-1-[(3S,8S,9S,10R,13S,14S,17S)-3-methoxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N,N-dimethylethanamine
SMILES CC(C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC)C)C)N(C)C
Standard InChIKey ZTNBSFMIFOLVCM-MCTVSQGJSA-N
Standard InChI InChI=1S/C24H41NO/c1-16(25(4)5)20-9-10-21-19-8-7-17-15-18(26-6)11-13-23(17,2)22(19)12-14-24(20,21)3/h7,16,18-22H,8-15H2,1-6H3/t16-,18-,19-,20+,21-,22-,23-,24+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pachyaximine A

The herbs of Pachysandra axillaris

Biological Activity of Pachyaximine A

Description1. Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. 2. (-)-Pachyaximine A demonstrates significant activity as antiestrogen binding site (AEBS)-inhibitory agents, and potentiates significantly the antiestrogenic effect mediated by tamoxifen in cultured Ishikawa cells.
TargetsEstrogen receptor | Antifection | Progestogen receptor

Pachyaximine A Dilution Calculator

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Pachyaximine A Molarity Calculator

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Preparing Stock Solutions of Pachyaximine A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7809 mL 13.9043 mL 27.8087 mL 55.6174 mL 69.5217 mL
5 mM 0.5562 mL 2.7809 mL 5.5617 mL 11.1235 mL 13.9043 mL
10 mM 0.2781 mL 1.3904 mL 2.7809 mL 5.5617 mL 6.9522 mL
50 mM 0.0556 mL 0.2781 mL 0.5562 mL 1.1123 mL 1.3904 mL
100 mM 0.0278 mL 0.139 mL 0.2781 mL 0.5562 mL 0.6952 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pachyaximine A

Anti-bacterial alkaloids of Saracococca saligna.[Pubmed:16431389]

Pak J Pharm Sci. 2005 Apr;18(2):3-5.

The crude ethanolic extract of Saracococca saligna was found to be cytotoxic and antibacterial but produced no platelet aggregation induced by ADP. Antibacterial activity of two known alkaloid, pachyaximine-A and saracodine was determined. Pachyaximine-A possessed significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. Saracodme showed moderate activity against Staphylococcus pyrogenes, Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae, Shigella boydii and Klebsiella pneumoniae.

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