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Pandamarilactonine B

CAS# 303008-81-3

Pandamarilactonine B

2D Structure

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Quality Control of Pandamarilactonine B

3D structure

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Pandamarilactonine B

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Chemical Properties of Pandamarilactonine B

Cas No. 303008-81-3 SDF Download SDF
PubChem ID 10734257 Appearance Oil
Formula C18H23NO4 M.Wt 317.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (5Z)-3-methyl-5-[4-[(2S)-2-[(2R)-4-methyl-5-oxo-2H-furan-2-yl]pyrrolidin-1-yl]butylidene]furan-2-one
SMILES CC1=CC(OC1=O)C2CCCN2CCCC=C3C=C(C(=O)O3)C
Standard InChIKey HSICZNIIIPFAAO-VFPQPWSNSA-N
Standard InChI InChI=1S/C18H23NO4/c1-12-10-14(22-17(12)20)6-3-4-8-19-9-5-7-15(19)16-11-13(2)18(21)23-16/h6,10-11,15-16H,3-5,7-9H2,1-2H3/b14-6-/t15-,16+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pandamarilactonine B

The barks of Pandanus amaryllifolius

Biological Activity of Pandamarilactonine B

DescriptionStandard reference
In vitro

Antimicrobial alkaloids from the leaves of Pandanus amaryllifolius[Reference: WebLink]

J. Appl. Pharm.Sci.,2015,5(10):151-3.


METHODS AND RESULTS:
Chemical investigation on the crude base of the Pandanus amaryllifolius leaves led to the isolation and identification of pandamarilactone-1 (1), pandamarilactone-32 (2), Pandamarilactonine A (3), and Pandamarilactonine B (4). Their structures were elucidated based on 1H and 13C NMR and in comparison with the literature data.
CONCLUSIONS:
Compound 3 was found to be the most active among the four isolates with an MIC of 15.6 ug/mL and MBC of 31.25 ug/mL against Pseudomonas aeruginosa. This is the first report on the antimicrobial activity of the isolated alkaloids from the genus Pandanus.

Pandamarilactonine B Dilution Calculator

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Preparing Stock Solutions of Pandamarilactonine B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1506 mL 15.753 mL 31.506 mL 63.012 mL 78.765 mL
5 mM 0.6301 mL 3.1506 mL 6.3012 mL 12.6024 mL 15.753 mL
10 mM 0.3151 mL 1.5753 mL 3.1506 mL 6.3012 mL 7.8765 mL
50 mM 0.063 mL 0.3151 mL 0.6301 mL 1.2602 mL 1.5753 mL
100 mM 0.0315 mL 0.1575 mL 0.3151 mL 0.6301 mL 0.7876 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pandamarilactonine B

Antimicrobial alkaloids from the leaves of Pandanus amaryllifolius

J. Appl. Pharm.Sci.,2015,5(10):151-3.

Chemical investigation on the crude base of the Pandanus amaryllifolius leaves led to the isolation and identification of pandamarilactone-1 (1), pandamarilactone-32 (2), Pandamarilactonine A (3), and Pandamarilactonine B (4). Their structures were elucidated based on 1H and 13C NMR and in comparison with the literature data. Compound 3 was found to be the most active among the four isolates with an MIC of 15.6 ug/mL and MBC of 31.25 ug/mL against Pseudomonas aeruginosa. This is the first report on the antimicrobial activity of the isolated alkaloids from the genus Pandanus.

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