Pelargonidin chlorideCAS# 134-04-3 |
Quality Control & MSDS
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| Cas No. | 134-04-3 | SDF | Download SDF |
| PubChem ID | 67249 | Appearance | Red-black powder |
| Formula | C15H11O5Cl | M.Wt | 306.7 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Synonyms | Pelargonidol chloride; 3,4',5,7-Tetrahydroxyflavylium chloride | ||
| Solubility | Soluble in methan | ||
| Chemical Name | 2-(4-hydroxyphenyl)chromenylium-3,5,7-triol;chloride | ||
| SMILES | C1=CC(=CC=C1C2=C(C=C3C(=CC(=CC3=[O+]2)O)O)O)O.[Cl-] | ||
| Standard InChIKey | YPVZJXMTXCOTJN-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C15H10O5.ClH/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15;/h1-7H,(H3-,16,17,18,19);1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Pelargonidin chloride has anti-diabetic activity. 2. Pelargonidin chloride has antioxidant and anti-inflammatory activities. 3. Pelargonidin chloride is a nitric oxide scavenger, inhibits iNOS protein and mRNA expression and also NO production in a dose-dependent manner. |
| Targets | NO | NOS |
Pelargonidin chloride Dilution Calculator
Pelargonidin chloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.2605 mL | 16.3026 mL | 32.6052 mL | 65.2103 mL | 81.5129 mL |
| 5 mM | 0.6521 mL | 3.2605 mL | 6.521 mL | 13.0421 mL | 16.3026 mL |
| 10 mM | 0.3261 mL | 1.6303 mL | 3.2605 mL | 6.521 mL | 8.1513 mL |
| 50 mM | 0.0652 mL | 0.3261 mL | 0.6521 mL | 1.3042 mL | 1.6303 mL |
| 100 mM | 0.0326 mL | 0.163 mL | 0.3261 mL | 0.6521 mL | 0.8151 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antigenotoxic effects of the phytoestrogen pelargonidin chloride and the polyphenol chlorogenic acid.[Pubmed:17579891]
Mol Nutr Food Res. 2007 Jul;51(7):880-7.
Pelargonidin (PEL), a common anthocyanidin with estrogenic activity, was tested in HL-60 cells for its genotoxicity and possible antigenotoxic effects against 4-nitroquinoline 1-oxide (NQO), a potent mutagen and carcinogen which induces oxidative stress. To take into account potential interactions between phytochemicals within normal human nutrition, we evaluated a combination of PEL with the nonestrogenic phytochemical chlorogenic acid (CLA), one of the most abundant polyphenols in the human diet. PEL (< or = 2 microM) and CLA (< or = 800 microM) were nongenotoxic in the micronucleus test. We observed significant antigenotoxic effects against NQO with both compounds, but no additive interaction of PEL and CLA. Comet assay results showed a nonsignificant reduction in NQO-induced DNA damage with both compounds and their combination. Flow cytometric analysis of oxidative stress revealed significant protection against NQO-induced oxidative stress by PEL, CLA, and their combination. Furthermore, PEL and CLA prevented the NQO-induced reduction in GSH level. This could be a mechanism for the observed reduction in genotoxicity. In conclusion, the phytoestrogen PEL revealed antioxidative and antigenotoxic properties in HL-60 cells, but no significant additive interaction with the abundant nutritional polyphenol CLA under the tested conditions.
Optimization of a new method for extraction of cyanidin chloride and pelargonidin chloride anthocyanins with magnetic solid phase extraction and determination in fruit samples by HPLC with central composite design.[Pubmed:28987497]
J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Nov 1;1067:38-44.
Here, we are reporting a sensitive, simple and rapid method for the analysis of cyanidin chloride and Pelargonidin chloride anthocyanins in cherry, sour cherry, pomegranate and barberry produced in Iran. The analytes were extracted with acetonitrile-hydrochloric acid (1% v/v) mixture under optimized pretreatment conditions. Clean-up of the extract from fruits was conducted by magnetic solid phase extraction using salicylic acid functionalized silica-coated magnetite nanoparticles (SCMNPs) as the adsorbent. The optimized conditions searched with central composite design. Working under optimum conditions specified as: SCMNPs modified with salicylic acid, sorbent contact time and sample 10min, mechanical stirring time 57.3min. HPLC with UV-detection was used for determination of the analytes. The limit of detection, LOD, obtained for the two anthocyanins were 0.02 and 0.03mugg(-1), respectively. The ranges of the spiked recoveries were 80.0-97.6 and 72.9-97.2%, with the relative standard deviations (RSD) of 2.1 and 2.5%, respectively.
