PiperundecalidineCAS# 88660-11-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
Cas No. | 88660-11-1 | SDF | Download SDF |
PubChem ID | N/A | Appearance | Powder |
Formula | C23H29NO3 | M.Wt | 367.48 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Piperundecalidine Dilution Calculator
Piperundecalidine Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.7212 mL | 13.6062 mL | 27.2124 mL | 54.4247 mL | 68.0309 mL |
5 mM | 0.5442 mL | 2.7212 mL | 5.4425 mL | 10.8849 mL | 13.6062 mL |
10 mM | 0.2721 mL | 1.3606 mL | 2.7212 mL | 5.4425 mL | 6.8031 mL |
50 mM | 0.0544 mL | 0.2721 mL | 0.5442 mL | 1.0885 mL | 1.3606 mL |
100 mM | 0.0272 mL | 0.1361 mL | 0.2721 mL | 0.5442 mL | 0.6803 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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In Silico Investigation of Phytoconstituents of Medicinal Herb 'Piper Longum' Against SARS-CoV-2 by Molecular Docking and Molecular Dynamics Analysis.[Pubmed:34603947]
Results Chem. 2021 Sep 24:100199.
Unavailability of treatment for the SARS-CoV-2 virus has raised concern among the population worldwide. This has led to many attempts to find alternative options to prevent the infection of the disease, including focusing on vaccines and drugs. The use of natural products and herbal extracts can be a better option in beating the virus and boosting up immunity. In the present paper, we have done a systematic in silico study of papain-like protease of COVID-19 virus with the chemical constituents of herbal plant Piper Longum. Screening of the pharmacokinetic properties is done with thirty-two phytoconstituents of Piper Longum which help us in selecting the most active components of the plant. After selection molecular docking is performed with Aristololactam (C(17)H(11)NO(4)), Fargesin (C(21)H(22)O(6)), l-asarinin (C(20)H(18)O(6)), Lignans Machilin F (C(20)H(22)O(5)), Piperundecalidine (C(23)H(29)NO(3)), and Pluviatilol (C(20)H(20)O(6)). Molecular dynamic (MD) is also performed with the inhibitor-receptor complex which suggest significant inhibition and a stable complex of I-Asarinin with PL(pro). Docking scores and simulation results suggest that I-Asarinin can act as a potential drug like candidate against COVID-19.
Overview for various aspects of the health benefits of Piper longum linn. fruit.[Pubmed:21704957]
J Acupunct Meridian Stud. 2011 Jun;4(2):134-40.
Herbal remedies have become popular, due in part to the lower risk of adverse reactions. Thousands of plants have been used traditionally to treat various diseases. Among them, species of the genus Piper are important medicinal plants used in various systems of medicine. The Piper longum fruit has been used in traditional medicine, including the Ayurvedic system of medicine. Although there are numerous indications for its use, controlled trials are needed to determine its efficacy. The primary constituents isolated from various parts of P. longum are piperine, piperlongumine, sylvatin, sesamin, diaeudesmin piperlonguminine, pipermonaline, and Piperundecalidine. It is most commonly used to treat chronic bronchitis, asthma, constipation, gonorrhea, paralysis of the tongue, diarrhea, cholera, chronic malaria, viral hepatitis, respiratory infections, stomachache, bronchitis, diseases of the spleen, cough, and tumors. This study provides detailed information about the P. longum fruit, including phytochemistry, pharmacological profile and safety profile. In view of the commercial, economic, and medicinal importance of the P. longum plant, it is useful for researchers to study the plant in detail.