Pterodondiol

CAS# 60132-35-6

Pterodondiol

Catalog No. BCN4110----Order now to get a substantial discount!

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Chemical structure

Pterodondiol

3D structure

Chemical Properties of Pterodondiol

Cas No. 60132-35-6 SDF Download SDF
PubChem ID 10879263 Appearance Cryst.
Formula C15H28O2 M.Wt 240.4
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,4aS,7R,8aS)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-1-ol
SMILES CC12CCCC(C1CC(CC2)C(C)(C)O)(C)O
Standard InChIKey LKKDASYGWYYFIK-DHMWGJHJSA-N
Standard InChI InChI=1S/C15H28O2/c1-13(2,16)11-6-9-14(3)7-5-8-15(4,17)12(14)10-11/h11-12,16-17H,5-10H2,1-4H3/t11-,12+,14+,15+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pterodondiol

The herbs of Laggera pterodonta (DC.) Benth.

Biological Activity of Pterodondiol

Description1. Pterodondiol has moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans.
TargetsAntifection

Pterodondiol Dilution Calculator

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Pterodondiol Molarity Calculator

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Preparing Stock Solutions of Pterodondiol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1597 mL 20.7987 mL 41.5973 mL 83.1947 mL 103.9933 mL
5 mM 0.8319 mL 4.1597 mL 8.3195 mL 16.6389 mL 20.7987 mL
10 mM 0.416 mL 2.0799 mL 4.1597 mL 8.3195 mL 10.3993 mL
50 mM 0.0832 mL 0.416 mL 0.8319 mL 1.6639 mL 2.0799 mL
100 mM 0.0416 mL 0.208 mL 0.416 mL 0.8319 mL 1.0399 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pterodondiol

Cytotoxic and antioxidant compounds from the stem bark of Goniothalamus tapisoides Mat Salleh.[Pubmed:23344192]

Molecules. 2012 Dec 21;18(1):128-39.

Eleven compounds:goniomicin A (1), goniomicin B (2), goniomicin C (3), goniomicin D (4), tapisoidin (5), goniothalamin (6), 9-deoxygoniopypyrone (7), Pterodondiol (8), liriodenine (9), benzamide (10) and cinnamic acid (11), were isolated from the stem bark of Goniothalamus tapisoides. All compounds were identified by spectroscopic analysis and, for known compounds, by comparison with published data. Goniothalamin (6) exhibited mild cytotoxic activity towards a colon cancer cell line (HT-29), with an IC(50)value of 64.17 +/- 5.60 microM. Goniomicin B (2) give the highest antioxidant activity in the DPPH assay among all compounds tested, with an IC(50) of 0.207 microM.

Terpenoids and flavonoids from Laggera pterodonta.[Pubmed:17703774]

Yao Xue Xue Bao. 2007 May;42(5):511-5.

To study the chemical constituents of aerial parts of Laggera pterodonta (DC.) Benth., the air-dried aerial parts of this plant were powered and extracted with boiling water and purified by silica gel column chromatography and recrystallized. Eleven compounds were obtained from L. pterodonta. They were identified as to be 6-O-beta-D-glucopyranosyl-carvotanacetone (1), pterodontic acid (2), 1beta-hydroxy pterondontic acid (3), pterodontoside A (4), Pterodondiol (5), pterodontriol B (6), 5-hydroxy-3,4', 6,7-tetramethoxyflavone (7), artemitin (8), chrysosplenetin B (9), quercetin (10) and beta-sitosterol (11). Compound 1 is a new monoterpene glucoside. Compounds 10 and 11 were isolated from this plant for the first time. Compounds 2 and 5 showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans by paper disc diffusion method, while they both displayed no activity against Escherichia coli.

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